Listar INIBIC-ICATC - Artigos por título

Mostrando ítems 91-110 de 173

    • Infectious complications associated with short-term mechanical circulatory support in urgent heart transplant candidates 

      Solla-Buceta, Miguel; González-Vílchez, Francisco; Almenar-Bonet, Luis; Lambert Rodríguez, José Luis; Segovia-Cubero, Javier; González-Costello, José; Delgado-Jiménez, Juan F.; Pérez-Villa, Félix; Crespo-Leiro, María Generosa; Rangel-Sousa, Diego; Martínez-Sellés, Manuel; Rábago, Gregorio; De-la-Fuente Galán, Luis; Blasco-Peiró, Teresa; Hervás-Sotomayor, Daniela; Garrido-Bravo, Iris P.; Mirabet, Sonia; Muñiz, Javier; Barge-Caballero, Eduardo (Elsevier, 2021-02-27)
      [Abstract] Introduction and objectives. Short-term mechanical circulatory support is frequently used as a bridge to heart transplant in Spain. The epidemiology and prognostic impact of infectious complications in these ...

    • Inotropic therapy in patients with advanced heart failure: a clinical consensus statement from the Heart Failure Association of the European Society of Cardiology 

      Gustafsson, Finn; Damman, Kevin; Nalbantgil, Sanem; Van Laake, Linda W.; Tops, Laurens F.; Thum, Thomas; Adamopoulos, Stamatis; Bonios, Michael; Coats, Andrew J.S.; Crespo-Leiro, María Generosa; Mehra, Mandeep R.; Filippatos, Gerasimos; Hill, Loreena; Metra, Marco; Jankowska, Ewa; de Jonge, Nicolaas; Kaye, David; Masetti, Marco; Parissis, John; Milicic, Davor; Seferovic, Petar; Rosano, Giuseppe; Ben Gal, Tuvia (John Wiley & Sons, 2023-02-27)
      [Abstract] This clinical consensus statement reviews the use of inotropic support in patients with advanced heart failure. The current guidelines only support use of inotropes in the setting of acute decompensated heart ...

    • International Consortium for Health Outcomes Measurement (ICHOM): standardized patient-centered outcomes measurement set for heart failure patients 

      Burns, Daniel J.P.; Arora, Jason; Okunade, Oluwakemi; Beltrame, John F.; Bernardez-Pereira, Sabrina; Crespo-Leiro, María Generosa; Filippatos, Gerasimos; Hardman, Suzanna; Hoes, Arno W.; Hutchinson, Steven; Jessup, Mariell; Kinsella, Tina; Knapton, Michael; Lam, Carolyn S.P.; Masoudi, Frederick A.; McIntyre, Hugh; Mindham, Richard; Morgan, Louise; Otterspoor, Luuk; Parker, Victoria; Peerson, Hans E.; Pinnock, Claude; Reid, Christopher M.; Riley, Jillian; Stevenson, Lynne W.; McDonagh, Theresa A. (American College of Cardiology Foundation, 2020-03)
      [Abstract] Whereas multiple national, international, and trial registries for heart failure have been created, international standards for clinical assessment and outcome measurement do not currently exist. The working ...

    • In‐hospital and 1‐year mortality associated with diabetes in patients with acute heart failure: results from the ESC‐HFA Heart Failure Long‐Term Registry 

      Targher, Giovanni; Dauriz, Marco; Laroche, Cecile; Temporelli, Pier Luigi; Hassanein, Mahmoud; Seferovic, Petar M.; Drozdz, Jaroslaw; Ferrari, Roberto; Anker, Stefan; Coats, Andrew; Filippatos, Gerasimos; Crespo-Leiro, María Generosa; Mebazaa, Alexandre; Piepoli, Massimo F.; Maggioni, Aldo P.; Tavazzi, Luigi (Wiley, 2016-10-28)
      [Abstract] AIMS: The aim of this study was to evaluate the in-hospital and 1-year prognostic impact of diabetes and elevated blood glucose levels at hospital admission in patients with acute heart failure (HF). METHODS ...

    • Is Becker dystrophinopathy a contraindication to heart transplant?: experience in a single institution 

      Ascencio-Lemus, Marisol Guadalupe; Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Crespo-Leiro, María Generosa (Elsevier, 2018-07-17)

    • Is degree of chronic illness management in heart transplant centers associated with better patient survival?: findings from the intercontinental BRIGHT study 

      Cajita, Maan Isabella; Denhaerynck, Kris; Berben, Lut; Dobbels, Fabienne; Van Cleemput, Johan; Crespo-Leiro, María Generosa; Van Keer, Jan; Poncelet, Alain Jean; Russell, Cynthia; De Geest, Sabina (SAGE, 2021-09-22)
      [Abstract] Purpose: To explore the association between the degree of Chronic illness management and survival rates at 1-, 3-, 5-years post heart transplantation. Methods: Exploratory secondary analysis of a cross-sectional, ...

    • Is heart failure misdiagnosed in hospitalized patients with preserved ejection fraction? From the European Society of Cardiology - Heart Failure Association EURObservational Research Programme Heart Failure Long-Term Registry 

      Kapłon-Cieślicka, Agnieszka; Laroche, Cécile; Crespo-Leiro, María Generosa; Coats, Andrew J.S.; Anker, Stefan; Filippatos, Gerasimos; Maggioni, Aldo P.; Hage, Camilla; Lara-Padrón, Antonio; Fucili, Alessandro; Drożdż, Jarosław; Seferovic, Petar M.; Rosano, Giuseppe; Mebazaa, Alexandre; McDonagh, Theresa A.; Lainscak, Mitja; Ruschitzka, Frank; Lund, Lars H. (Wiley Online Library, 2020-07-02)
      [Abstract] Aims. In hospitalized patients with a clinical diagnosis of acute heart failure (HF) with preserved ejection fraction (HFpEF), the aims of this study were (i) to assess the proportion meeting the 2016 European ...

    • Ischemic cardiomyopathy versus non-ischemic dilated cardiomyopathy in patients with reduced ejection fraction-clinical characteristics and prognosis depending on heart failure etiology (data from European Society of Cardiology heart failure registries) 

      Tyminska, Agata; Ozieranski, Krzysztof; Balsam, Pawel; Maciejewski, Cezary; Wancerz, Anna; Brociek, Emil; Marchel, Michal; Crespo-Leiro, María Generosa; Maggioni, Aldo P.; Drozdz, Jaroslaw; Opolski, Grzegorz; Grabowski, Marcin; Kapłon-Cieslicka, Agnieszka (MDPI, 2022-02-21)
      [Abstract] Personalized management involving heart failure (HF) etiology is crucial for better prognoses for HF patients. This study aimed to compare patients with ischemic cardiomyopathy (ICM) and patients with non-ischemic ...

    • Left ventricular ejection fraction digit bias and reclassification of heart failure with mildly reduced vs reduced ejection fraction based on the 2021 definition and classification of heart failure 

      Savarese, Gianluigi; Gatti, Paolo; Benson, Lina; Adamo, Marianna; Chioncel, Ovidiu; Crespo-Leiro, María Generosa; Anker, Stefan D.; Coats, Andrew J.S.; Filippatos, Gerasimos; Lainscak, Mitja; Mcdonagh, Theresa; Mebazaa, Alexandre; Metra, Marco; Piepoli, Massimo; Rosano, Giuseppe M.; Ruschitzka, Frank; Seferovic, Petar; Volterrani, Maurizio; Maggioni, Aldo P.; Lund, Lars H. (Elsevier, 2023-11-15)
      [Abstract] Aims: Aims were to evaluate (1) reclassification of patients from heart failure with mildly reduced (HFmrEF) to reduced (HFrEF) ejection fraction when an EF = 40% was considered as HFrEF, (2) role of EF digit ...

    • Levosimendan Efficacy and Safety: 20 Years of SIMDAX in Clinical Use 

      Papp, Zoltán; Álvarez, Julián; Bettex, Dominique; Bouchez, Stefan; Brito, Dulce; Černý, Vladimir; Comin-Colet; Comin-Colet, Josep; Crespo-Leiro, María Generosa; Delgado-Jiménez, Juan F.; Édes, István; Eremenko, Alexander; Farmakis, Dimitrios; Fedele, Francesco; Fonseca, Candida; Fruhwald, Sonja; Girardis, Massimo; Guarracino, Fabio; Harjola, Veli-Pekka; Heringlake, Matthias; Herpain, Antoine; Heunks, Leo; Husebye, Tryggve; Ivancan, Višnja; Karason, Kristjan; Kaul, Sundeep; Kivikko, Matti; Kubica, Janek; Masip, Josep; Matskeplishvili, Simon; Mebazaa, Alexandre; Nieminen, Markku S.; Oliva, Fabrizio; Papp, Julius G.; Parissis, John; Parkhomenko, Alexander; Põder, Pentti; Pölzl, Gerhard; Reinecke, Alexander; Ricksten, Sven-Erik; Riha, Hynek; Rudiger, Alain; Sarapohja, Toni; Schwinger, Robert H. G.; Toller, Wolfgang; Tritapepe, Luigi; Tschöpe, Carsten; Wikström, Gerhard; Lewinski, Dirk von; Vrtovec, Bojan; Pollesello, Piero; Agostoni, Piergiuseppe (Wolters Kluwer, 2020-07)
      [Abstract] Levosimendan was first approved for clinical use in 2000, when authorization was granted by Swedish regulatory authorities for the hemodynamic stabilization of patients with acutely decompensated chronic heart ...

    • Light Chain and Transthyretin Cardiac Amyloidosis: Clinical Characteristics, Natural History and Prognostic Factors 

      Barge-Caballero, Gonzalo; Vázquez-García, Raquel; Barge-Caballero, Eduardo; Couto-Mallón, David; Paniagua-Martín, María J.; Barriales-Villa, Roberto; Piñón-Esteban, Pablo; Bouzas-Mosquera, Alberto; Pombo-Otero, Jorge; Debén-Ariznavarreta, Guillermo; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2021-03-13)
      [Abstract] Introduction and objectives. Light-chain amyloidosis (AL-CA) and transthyretin amyloidosis (ATTR-CA) are the most common types of cardiac amyloidosis (CA). We sought to study the clinical characteristics and ...

    • Malignancy following heart transplantation: differences in incidence and prognosis between sexes – a multicenter cohort study 

      Minguito‐Carazo, Carlos; Gómez-Bueno, Manuel; Almenar‐Bonet, Luis; Barge-Caballero, Eduardo; González-Vílchez, Francisco; Delgado-Jiménez, Juan F.; Arizón-del-Prado, José M.; Sousa-Casasnovas, Iago; Mirabet, Sonia; González-Costello, José; Sobrino-Márquez, José Manuel; Pérez-Villa, Félix; Díaz Molina, Beatriz; Rábago, Gregorio; Blasco-Peiró, Teresa; De la Fuente-Galán, Luis; Garrido-Bravo, Iris P.; García-Guereta, Luis; Camino, Manuela; Albert-Brotons, Dimpna C.; Muñiz, Javier; Crespo-Leiro, María Generosa (Wiley Online Library, 2021-03-12)
      [Abstract] Male patients are at increased risk for developing malignancy postheart transplantation (HT); however, real incidence and prognosis in both genders remain unknown. The aim of this study was to assess differences ...

    • Many heart transplant biopsies currently diagnosed as no rejection have mild molecular antibody-mediated rejection-related changes 

      Halloran, Philip F.; Madill-Thomsen, Katelynn; Aliabadi-Zuckermann, Arezu Z.; Cadeiras, Martín; Crespo-Leiro, María Generosa; Depasquale, Eugene C.; Deng, Mario; Gökler, Johannes; Kim, Daniel H.; Kobashigawa, Jon; Macdonald, Peter; Potena, Luciano; Shah, Keyur; Stehlik, Josef; Zuckermann, Andreas (Elsevier, 2021-08-04)
      [Abstract] Background: The Molecular Microscope (MMDx) system classifies heart transplant endomyocardial biopsies as No-rejection (NR), Early-injury, T cell-mediated (TCMR), antibody-mediated (ABMR), mixed, and possible ...

    • Mitochondrial DNA haplogroup H as a risk factor for idiopathic dilated cardiomyopathy in Spanish population 

      Fernández Caggiano, Mariana; Barallobre-Barreiro, Javier; Rego-Pérez, Ignacio; Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Grille Cancela, Zulaika; Blanco García, Francisco J; Doménech, Nieves (Elsevier, 2013-03-23)
      [Abstract] Idiopathic dilated cardiomyopathy (IDC) is a structural heart disease with strong genetic background. The different single nucleotide polymorphisms (SNPs) that constitute mitochondrial haplogroups could play an ...

    • Mitochondrial Pyruvate Carrier Abundance Mediates Pathological Cardiac Hypertrophy 

      Fernández-Caggiano, Mariana; Kamynina, Alisa; Francois, Asvi A.; Prysyazhna, Oleksandra; Eykyn, Thomas R.; Krasemann, Susanne; Crespo-Leiro, María Generosa; García-Vieites, M.; Bianchi, Katiuscia; Morales, Valle; Doménech, Nieves; Eaton, Philip (Springer Nature, 2020-10-26)
      [Abstract] Cardiomyocytes rely on metabolic substrates, not only to fuel cardiac output, but also for growth and remodelling during stress. Here we show that mitochondrial pyruvate carrier (MPC) abundance mediates ...

    • Molecular states associated with dysfunction and graft loss in heart transplants 

      Halloran, Philip F.; Madill-Thomsen, Katelynn; Mackova, Martina; Aliabadi-Zuckermann, Arezu Z.; Cadeiras, Martin; Crespo-Leiro, María Generosa; Depasquale, Eugene C.; Deng, Mario; Gökler, Johannes; Hall, Shelley A.; Kim, Daniel H.; Kobashigawa, Jon; Macdonald, Peter; Potena, Luciano; Shah, Keyur; Stehlik, Josef; Zuckermann, Andreas; Reeve, Jeff (Elsevier, 2023-11-30)
      [Abstract] Background: We explored the changes in gene expression correlating with dysfunction and graft failure in endomyocardial biopsies. Methods: Genome-wide microarrays (19,462 genes) were used to define mRNA ...

    • Multi-omics approach reveals prebiotic and potential antioxidant effects of essential oils from the mediterranean diet on cardiometabolic disorder using humanized gnotobiotic mice 

      Sánchez-Quintero, María José; Delgado, Josué; Martín Chaves, Laura; Medina-Vera, Dina; Murri, Mora; Becerra-Muñoz, Víctor M.; Estévez, Mario; Crespo-Leiro, María Generosa; Paz López, Guillermo; González-Jiménez, Andrés; García Ranea, Juan A.; Queipo-Ortuño, María Isabel; Plaza-Andrades, Isaac; Rodríguez-Capitán, Jorge; Pavón-Morón, Francisco Javier; Jiménez-Navarro, Manuel (MDPI, 2023-08-20)
      [Abstract] Essential oils sourced from herbs commonly used in the Mediterranean diet have demonstrated advantageous attributes as nutraceuticals and prebiotics within a model of severe cardiometabolic disorder. The primary ...

    • Multilevel factors are associated with immunosuppressant nonadherence in heart transplant recipients: the international BRIGHT study 

      Denhaerynck, Kris; Berben, Lut; Dobbels, Fabienne; Russell, Cynthia L.; Crespo-Leiro, María Generosa; Poncelet, Alain Jean; De Geest, Sabina (Elsevier, 2017-12-05)
      [Abstract] Factors at the level of family/healthcare worker, organization, and system are neglected in medication nonadherence research in heart transplantation (HTx). The 4-continent, 11-country cross-sectional Building ...

    • Omecamtiv mecarbil for patients with severe systolic dysfunction and hypotension 

      Crespo-Leiro, María Generosa; McDonagh, Theresa A.; Barge-Caballero, Eduardo (Oxford Academic, 2022-12-21)

    • Omecamtiv Mecarbil in Chronic Heart Failure With Reduced Ejection Fraction: GALACTIC‐HF Baseline Characteristics and Comparison With Contemporary Clinical Trials 

      Teerlink, John R.; Díaz, Rafael; Felker, G. Michael; McMurray, John J.V.; Metra, Marco; Solomon, Scott D.; Adams, Kirkwood F.; Anand, Inder; Arias‐Mendoza, Alexandra; Biering‐Sørensen, Tor; Böhm, Michael; Bonderman, Diana; Cleland, John G.F.; Corbalán, Ramón; Crespo-Leiro, María Generosa; Dahlström, Ulf; Echeverría Correa, Luis E.; Fang, James C.; Filippatos, Gerasimos; Fonseca, Cándida; Goncalvesova, Eva; Goudev, Assen R.; Howlett, Jonathan G.; Lanfear, David E.; Lund, Mayanna; Macdonald, Peter; Mareev, Vyacheslav; Momomura, Shin‐ichi; O'Meara, Eileen; Parkhomenko, Alexander; Ponikowski, Piotr; Ramires, Felix J.A.; Serpytis, Pranas; Sliwa, Karen; Spinar, Jindrich; Suter, Thomas M.; Tomcsanyi, Janos; Vandekerckhove, Hans; Vinereanu, Dragos; Voors, Adriaan A.; Yilmaz, Mehmet B.; Zannad, Faiez; Sharpsten, Lucie; Legg, Jason C.; Abbasi, Siddique A.; Varin, Claire; Malik, Fady I.; Kurtz, Christopher E. (Willey Online Library, 2020-09-20)
      [Abstract] Aims The safety and efficacy of the novel selective cardiac myosin activator, omecamtiv mecarbil, in patients with heart failure with reduced ejection fraction (HFrEF) is being tested in the Global Approach ...