Now showing items 19-38 of 159

    • Beneficial effects of essential oils from the mediterranean diet on gut microbiota and their metabolites in ischemic heart disease and type-2 diabetes mellitus 

      Sánchez-Quintero, María José; Delgado, Josué; Medina-Vera, Dina; Becerra-Muñoz, Víctor M.; Queipo-Ortuño, María Isabel; Estévez, Mario; Plaza-Andrades, Isaac; Rodríguez-Capitán, Jorge; Sánchez, Pedro L.; Crespo-Leiro, María Generosa; Jiménez-Navarro, Manuel F.; Pavón-Morón, Francisco Javier (MDPI, 2022-11-03)
      [Abstract] Ischemic heart disease (IHD) and type-2 diabetes mellitus (T2DM) remain major health problems worldwide and commonly coexist in individuals. Gut microbial metabolites, such as trimethylamine N-oxide (TMAO) and ...
    • Beta-blocker exposure and survival in patients with transthyretin amyloid cardiomyopathy 

      Barge-Caballero, Gonzalo; Barge-Caballero, Eduardo; López-Pérez, Manuel; Bilbao-Quesada, Raquel; González-Babarro, Eva; Gómez-Otero, Inés; López-López, Andrea; Gutiérrez-Feijoo, Mario; Varela-Román, Alfonso; González-Juanatey, Carlos; Díaz-Castro, Óscar; Crespo-Leiro, María Generosa (Elsevier, 2022-02)
      [Abstract] Objective: To investigate a potential association between beta-blocker exposure and survival in patients with transthyretin amyloid cardiomyopathy (ATTR-CM). Methods: In this real-world prospective registry ...
    • Body surface area as a prognostic marker in chronic heart failure patients: results from the Heart Failure Registry of the Heart Failure Association of the European Society of Cardiology 

      Zafrir, Barak; Salman, Nabeeh; Crespo-Leiro, María Generosa; Anker, Stefan; Coats, Andrew J.; Ferrari, Roberto; Filippatos, Gerasimos; Maggioni, Aldo P.; Mebazaa, Alexandre; Piepoli, Massimo Francesco; Ruschitzka, Frank; Paniagua-Martín, María J.; Segovia-Cubero, Javier; Laroche, Cecile; Amir, Offer (Wiley, 2016-07-18)
      [Abstract] AIMS: The 'obesity paradox' is consistently observed in patients with heart failure (HF). We investigated the relationship of body surface area (BSA) to mortality and hospitalizations in patients with chronic ...
    • Brachial pulse pressure in acute heart failure. Results of the Heart Failure Registry 

      Bonapace, Stefano; Rossi, Andrea; Laroche, Cécile; Crespo-Leiro, María Generosa; Piepoli, Massimo F.; Coats, Andrew J. S.; Dahlström, Ulf; Malek, Filip; Macarie, Cezar; Temporelli, Pier Luigi; Maggioni, Aldo P.; Tavazzi, Luigi (Willey Online Library, 2019-12-09)
      [Abstract] Aims To investigate the still uncertain independent prognostic impact of pulse pressure (PP) in acute heart failure (HF), in particular across the left ventricular ejection fraction (EF) phenotypes, and the ...
    • Building research initiative group: chronic illness management and adherence in transplantation (BRIGHT) study: study protocol 

      Berben, Lut; Denhaerynck, Kris; Dobbels, Fabienne; Engberg, Sandra; Vanhaecke, Johan; Crespo-Leiro, María Generosa; Russell, Cynthia L.; De Geest, Sabina (Wiley, 2014-09-26)
      [Abstract] AIM: This article describes the rationale, design and methodology of the Building research initiative group: chronic illness management and adherence in transplantation (BRIGHT) study. This study of heart ...
    • Calidad de vida relacionada con la salud de los pacientes con insuficiencia cardiaca crónica sistólica en España: resultados del estudio VIDA-IC 

      Comín, Josep; Anguita, Manuel; Formiga, Francesc; Almenar, Luis; Crespo-Leiro, María Generosa; Manzano, Luis; Muñiz, Javier; Chaves, José; Frutos, Trinidad de; Enjuanes, Cristina (Elsevier, 2015-12-23)
      [Resumen] Introducción y objetivos. La calidad de vida relacionada con la salud de los pacientes con insuficiencia cardiaca está afectada. Hay poca información sobre los factores clínicos asociados a esta mala calidad de ...
    • Cancer in patients with heart failure: incidence, risk factors and prognostic impact 

      Sagastagoitia-Fornie, Marta; Barge-Caballero, Eduardo; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Enríquez-Vázquez, Daniel; Blanco-Canosa, Paula; Grille-Cancela, Zulaika; Jiménez-Navarro, Manuel; Muñiz, Javier; Vázquez-Rodríguez, José M.; Crespo-Leiro, María Generosa (Elsevier, 2022-09-16)
      [Abstract] Aims: To assess the incidence of cancer diagnosis and cancer-related mortality in patients with heart failure (HF). Methods: Observational study based in a prospective cohort of patients with HF referred to ...
    • Cardiac amyloidosis: description of a series of 143 cases 

      Barge-Caballero, Gonzalo; Barge-Caballero, Eduardo; López-Pérez, Manuel; Bilbao-Quesada, Raquel; González-Babarro, Eva; Gómez-Otero, Inés; López-López, Andrea; Gutiérrez-Feijoo, Mario; Varela-Román, Alfonso; González-Juanatey, Carlos; Díaz-Castro, Óscar; Crespo-Leiro, María Generosa (Elsevier, 2022-09-09)
      [Abstract] Introduction and objectives: Recently, there have been important advances in the diagnosis and treatment of cardiac amyloidosis (CA). Our aim was to provide an updated description of its 2 most frequent types: ...
    • Cardiac Myosin Activation with Omecamtiv Mecarbil in Systolic Heart Failure 

      Teerlink, John R.; Díaz, Rafael; Felker, G. Michael; McMurray, John J.V.; Metra, Marco; Solomon, Scott D.; Adams, Kirkwood F.; Anand, Inder; Arias‐Mendoza, Alexandra; Biering‐Sørensen, Tor; Böhm, Michael; Bonderman, Diana; Cleland, John G.F.; Corbalán, Ramón; Crespo-Leiro, María Generosa; Dahlström, Ulf; Echeverría Correa, Luis E.; Fang, James C.; Filippatos, Gerasimos; Fonseca, Cándida; Goncalvesova, Eva; Goudev, Assen R.; Howlett, Jonathan G.; Lanfear, David E.; Li, J.; Lund, Mayanna; Macdonald, Peter; Mareev, Vyacheslav; Momomura, Shin‐ichi; O'Meara, Eileen; Parkhomenko, Alexander; Ponikowski, Piotr; Ramires, Felix J.A.; Serpytis, Pranas; Sliwa, Karen; Spinar, Jindrich; Suter, Thomas M.; Tomcsanyi, Janos; Vandekerckhove, Hans; Vinereanu, Dragos; Voors, Adriaan A.; Yilmaz, Mehmet B.; Zannad, Faiez; Sharpsten, Lucie; Legg, Jason C.; Varin, Claire; Honarpour, N.; Abbasi, Siddique A.; Malik, Fady I.; Kurtz, Christopher E. (Massachusetts Medical Society, 2020-11-13)
      [Abstract] BACKGROUND. The selective cardiac myosin activator omecamtiv mecarbil has been shown to improve cardiac function in patients with heart failure with a reduced ejection fraction. Its effect on cardiovascular ...
    • Cardiac Protection Induced by Urocortin-2 Enables the Regulation of Apoptosis and Fibrosis After Ischemia and Reperfusion Involving miR-29a Modulation 

      Mayoral-González, Isabel; Calderón-Sánchez, Eva M.; Galeano-Otero, Isabel; Martín-Bórnez, Marta; Gutiérrez-Carretero, Encarnación; Fernández-Velasco, María; Doménech, Nieves; Crespo-Leiro, María Generosa; Gómez, Ana María; Ordoñez-Fernández, Antonio; Hmadcha, Abdelkrim; Smani, Tarik (Elsevier, 2022-01-28)
      [Abstract] Urocortin-2 (Ucn-2) has demonstrated cardioprotective actions against myocardial ischemia-reperfusion (I/R) injuries. Herein, we explored the protective role of Ucn-2 through microRNAs (miRNAs) post-transcriptional ...
    • Cardiogenic shock code 2023: expert document for a multidisciplinary organization that allows quality care 

      Martínez-Sellés, Manuel; Hernández-Pérez, Francisco José; Uribarri, Aitor; Martín Villén, Luis; Zapata, Luis; Alonso, Joaquín C.; Amat-Santos, Ignacio C.; Ariza-Solé, Albert; Barrabés, José A.; Barrio, José María; Canteli, Ángela; Alonso-Fernández-Gatta, Marta; Corbí Pascual, Miguel J.; Díaz, Domingo; Crespo-Leiro, María Generosa; de la Torre-Hernández, José María; Ferrera, Carlos; García González, Martín J.; García-Carreño, Jorge; García-Guereta, Luis; García Quintana, Antonio; Jorge Pérez, Pablo; González-Juanatey, J.R.; López de Sá, Esteban; Sánchez, Pedro Luis; Monteagudo, María; Palomo López, Nora; Reyes, Guillermo; Rosell, Fernando; Solla-Buceta, Miguel; Segovia-Cubero, Javier; Sionis Green, Alessandro; Stepanenko, Alexander; Iglesias Álvarez, Diego; Viana Tejedor, Ana; Voces, Roberto; Fuset Cabanes, María Paz; Gimeno Costa, José Ricardo; Díaz, José; Fernández-Avilés, Francisco (Elsevier, 2022-12-21)
      [Abstract] Despite the efforts made to improve the care of cardiogenic shock (CS) patients, including the development of mechanical circulatory support (MCS), the prognosis of these patients continues to be poor. In this ...
    • Chronic renal dysfunction in maintenance heart transplant patients: the ICEBERG study 

      González-Vílchez, Francisco; Arizón-del-Prado, José M.; Segovia-Cubero, Javier; Almenar-Bonet, Luis; Crespo-Leiro, María Generosa; Palomo, Jesús; Delgado Jiménez, Juan Francisco; Mirabet, Sonia; Rábago, Gregorio; Pérez-Villa, Félix; Díaz, Beatriz; Sanz, M.L.; Pascual, Domingo; Fuente, Luis de la; Guinea, G. (Elsevier, 2014-02-05)
      [Abstract] Chronic renal dysfunction (CRD) is a major complication after heart transplantation. We sought to describe the renal function over time, to assess the risk factors associated with CRD development, and to evaluate ...
    • Circulating Galectin-3 Following Heart Transplant: Long-term Dynamics and Prognostic Value 

      Suárez-Fuentetaja, Natalia; Barge-Caballero, Eduardo; Bayés-Genís, Antoni; Doménech, Nieves; Moreda-Santamaría, Lucía; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Solla-Buceta, Miguel; Estévez-Cid, Francisco; Cuenca-Castillo, José J.; Pombo-Otero, Jorge; Grille-Cancela, Zulaika; Blanco-Canosa, Paula; Muñiz, Javier; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2018-11-23)
      [Abstract] Introduction and objectives: Circulating galectin-3 (Gal-3) is elevated and significantly correlates with all-cause and cardiovascular mortality in patients with heart failure. However, the relationship between ...
    • Circulating miR-181a-5p as a New Biomarker for Acute Cellular Rejection in Heart Transplantation 

      Constanso-Conde, Ignacio; Hermida-Prieto, Manuel; Barge-Caballero, Eduardo; Núñez, Lucía; Pombo-Otero, Jorge; Suárez-Fuentetaja, Natalia; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Pan Lizcano, Ricardo Francisco; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2020-06-07)
      [Abstract] Background: Acute cellular rejection (ACR) is a major complication in heart transplantation (HTx). Endomyocardial biopsy is the reference method for early detection of ACR, but a new non-invasive approach is ...
    • Clinical Characteristics and Long-term outcomes of patients undergoing combined heart-kidney transplantation: a single-center experience 

      López-Sainz, A.; Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Sánchez-Fernández, G.; Fernández Arias, L.; García-Vieites, M.; Alonso-Hernández, Á.; Rodríguez-Rivera-García, J.J.; Crespo-Leiro, María Generosa (Elsevier, 2015-01-30)
      [Abstract] Background. The purpose of the study was to describe clinical characteristics and long-term survival of patients undergoing combined heart-kidney transplant in a single center. Methods. We conducted a retrospective ...
    • Clinical evaluation of rosuvastatin in heart transplant patients with hypercholesterolemia and therapeutic failure of other statin regimens: short-term and long-term efficacy and safety results 

      Barge-Caballero, Gonzalo; Barge-Caballero, Eduardo; Marzoa Rivas, Raquel; Paniagua-Martín, María J.; Barrio-Rodríguez, Alfredo; Naya, Carmen; Blanco-Canosa, Paula; Grille Cancela, Zulaika; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Wiley, 2015-04-23)
      [Abstract] We conducted an observational study of 30 heart transplant recipients with serum low-density lipoprotein cholesterol (LDL-c) >100 mg/dl despite previous statin therapy, who were treated with rosuvastatin 10 mg ...
    • Clinical outcomes in heart transplant recipients with coronary abnormalities in the donor graft 

      Fernández de-Aspe, Pablo; Barge-Caballero, Eduardo; Aldama López, Guillermo; Fernández-Arias, Laura; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2023-02-02)
    • Clinical usefulness of gene-expression profile to rule out acute rejection after heart transplantation: CARGO II 

      Crespo-Leiro, María Generosa; Stypmann, Jörg; Schulz, Uwe; Zuckermann, Andreas; Mohascsi, Paul; Bara, Christian; Ross, Heather; Parameshwar, Jayan; Zakliczynski, Michal; Fiocchi, Roberto; Hoefer, Daniel; Colvin, Monica; Deng, Mario; Leprince, Pascal; Elashoff, Barbara; Yee, James P.; Vanhaecke, Johan (Oxford University Press en nombre de European Society of Cardiology, 2016-01-07)
      [Abstract] Aims. A non-invasive gene-expression profiling (GEP) test for rejection surveillance of heart transplant recipients originated in the USA. A European-based study, Cardiac Allograft Rejection Gene Expression ...
    • Clinical utility of genetic testing in patients with dilated cardiomyopathy 

      Peña-Peña, María Luisa; Ochoa, Juan Pablo; Barriales-Villa, Roberto; Cicerchia, Marcos; Palomino-Doza, Julián; Salazar-Mendiguchia, Joel; Lamounier, Arsonval; Trujillo, Juan Pablo; García-Giustiniani, Diego; Fernández, Xusto; Ortiz-Genga, Martín; Monserrat, Lorenzo; Crespo-Leiro, María Generosa (Elsevier, 2021-05)
      [Abstract] Introduction and objectives: Dilated cardiomyopathy (DCM) is the most frequent cause of heart transplantation. The prevalence of familial disease can reach 50%. Our objective was to describe the genetic basis ...
    • Cold Ischemia >4 Hours Increases Heart Transplantation Mortality. An Analysis of the Spanish Heart Transplantation Registry 

      Valero-Masa, María Jesús; González-Vílchez, Francisco; Almenar-Bonet, Luis; Crespo-Leiro, María Generosa; Manito-Lorite, Nicolás; Sobrino-Márquez, José Manuel; Gómez-Bueno, Manuel; Delgado Jiménez, Juan Francisco; Pérez-Villa, Félix; Brossa-Loidi, Vicens; Arizón-del-Prado, José M.; Díaz-Molina, Beatriz; Fuente Galán, Luis de la; Portolés-Ocampo, Ana; Garrido-Bravo, Iris P.; Rábago, Gregorio; Martínez-Sellés, Manuel (Elsevier, 2020-06-20)
      [Abstract] Background. Cold ischemia time (CIT) has been associated to heart transplantation (HT) prognosis. However, there is still uncertainty regarding the CIT cutoff value that might have relevant clinical ...