• Impact of Donor-Recipient Age on Cardiac Transplant Survival. Subanalysis of the Spanish Heart Transplant Registry 

      López-Vilella, Raquel; González-Vílchez, Francisco; Crespo-Leiro, María Generosa; Segovia-Cubero, Javier; Cobo, Manuel; Delgado Jiménez, Juan Francisco; Arizón-del-Prado, José M.; Martínez-Sellés, Manuel; Sobrino-Márquez, José Manuel; Mirabet, Sonia; González-Costello, José; Pérez-Villa, Félix; Lambert Rodríguez, José Luis; Rábago, Gregorio; Blasco-Peiró, Teresa; De la Fuente-Galán, Luis; Garrido-Bravo, Iris P.; Otero, Déborah; Almenar-Bonet, Luis (Elsevier, 2020-06-26)
      [Abstract] Introduction and objectives. The age of heart transplant recipients and donors is progressively increasing. It is likely that not all donor-recipient age combinations have the same impact on mortality. The ...
    • Impact of intrapatient blood level variability of calcineurin inhibitors on heart transplant outcomes 

      González-Vílchez, Francisco; Crespo-Leiro, María Generosa; Delgado-Jiménez, Juan F.; Pérez-Villa, Félix; Segovia-Cubero, Javier; Díaz-Molina, Beatriz; Mirabet, Sonia; Arizón-del-Prado, José M.; Blasco-Peiró, Teresa; Martínez-Sellés, Manuel; Almenar-Bonet, Luis; Garrido-Bravo, Iris P.; Rábago, Gregorio; Vázquez de Prada, José A. (Elsevier, 2021-03-18)
      [Abstract] Introduction and objectives. Intrapatient blood level variability (IPV) of calcineurin inhibitors has been associated with poor outcomes in solid-organ transplant, but data for heart transplant are scarce. ...
    • Implante transaxilar del dispositivo de asistencia circulatoria Impella CP como puente al trasplante cardiaco: primera experiencia en España 

      Couto-Mallón, David; Estévez-Cid, Francisco; Solla-Buceta, Miguel; García-Velasco, Carlos; Crespo-Leiro, María Generosa; Cuenca-Castillo, José J. (Elsevier, 2017-10-14)
    • In-hospital heart rate reduction and its relation to outcomes of heart failure patients with sinus rhythm: results from the polish part of the European Society of Cardiology Heart Failure pilot and long-term registries 

      Balsam, Pawel; Peller, Michal; Borodzicz, Sonia; Kaplon-Cieslicka, Agnieszka; Ozieranski, Krzysztof; Tyminska, Agata; Marchel, Michal; Crespo-Leiro, María Generosa; Maggioni, Aldo; Drozdz, Jaroslaw; Grabowski, Marcin; Filipiak, Krzysztof J.; Opolski, Grzegorz (Via Medica, 2018-08-29)
      [Abstract] Background: Currently, there is no information on whether in-hospital heart rate (HR) reduction has an influence on risk of death or rehospitalization. The study evaluates the relation between inhospital HR ...
    • In-Hospital Post-Operative Infection after Heart Transplantation: Epidemiology, Clinical Management, and Outcome 

      Gómez-López, Rocío; Barge-Caballero, Eduardo; Fernández-Ugidos, Paula; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Solla-Buceta, Miguel; Velasco-García de Sierra, Carlos; Aller-Fernández, Vanesa; Fernández-Arias, Laura; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Mary Ann Liebert, 2020-02-13)
      [Abstract] Background: Infection is a major cause of morbidity and mortality after heart transplantation (HT). Little information about its importance in the immediate post-operative period is available. The aim of this ...
    • In-hospital postoperative infection after heart transplantation: risk factors and development of a novel predictive score 

      Fernández-Ugidos, Paula; Barge-Caballero, Eduardo; Gómez-López, Rocío; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Solla-Buceta, Miguel; Iglesias-Gil, Carmen; Aller-Fernández, Vanesa; González-Barbeito, Miguel; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Wiley, 2019-05-11)
      [Abstract] Introduction: Infection is one of the most significant complications following heart transplantation (HT). The aim of this study was to identify specific risk factors for early postoperative infections in HT ...
    • Incidence and prognosis of colorectal cancer after heart transplantation: data from the spanish post-heart transplant tumor registry 

      Sagastagoitia-Fornie, Marta; Morán-Fernández, Laura; Blázquez-Bermejo, Zorba; Díaz-Molina, Beatriz; Gómez-Bueno, Manuel; Almenar-Bonet, Luis; López Granados, Amador; González-Vílchez, Francisco; Mirabet-Pérez, Sonia; García-Romero, Elena; Sobrino-Márquez, José Manuel; Rábago Juan-Aracil, Gregorio; Castel-Lavilla, María Ángeles; Blasco-Peiró, Teresa; Garrido-Bravo, Iris P.; De la Fuente-Galán, Luis; Muñiz, Javier; Crespo-Leiro, María Generosa (Frontiers, 2023-05)
      [Abstract] In this observational and multicenter study, that included all patients who underwent a heart transplantation (HT) in Spain from 1984 to 2018, we analyzed the incidence, management, and prognosis of colorectal ...
    • Incidence, Risk Factors and Prognostic Impact of Cytomegalovirus Infection After Heart Transplantation 

      Méndez-Eirín, Elizabet; Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Grille Cancela, Zulaika; Blanco-Canosa, Paula; Cañizares-Castellanos, Angelina; González Barbeito, Miguel; Aller Fernández, Ana Vanesa; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2020-03-20)
      [Abstract] Introduction and objectives. To assess the risk factors of CMV infection after heart transplant (HT) and its influence on long-term prognosis. Methods. We conducted a retrospective single-centre study of ...
    • Indications, complications, and outcomes of cardiac surgery after heart transplantation: results from the cash study 

      Gökler, Johannes; Aliabadi-Zuckermann, Arezu Z.; Kaider, Alexandra; Ambardekar, Amrut V.; Antretter, Herwig; Artemiou, Panagiotis; Bertolotti, Alejandro M.; Boeken, Udo; Brossa, Vicens; Copeland, Hannah; Crespo-Leiro, María Generosa; Eixeré-Esteve, Andrea; Epailly, Eric; Farag, Mina; Hulman, Michal; Khush, Kiran K.; Masetti, Marco; Patel, Jignesh; Ross, Heather J.; Rudez, Igor; Silvestry, Scott; Martín Suárez, Sofía; Vest, Amanda; Zuckermann, Andreas O. (Frontiers, 2022-06-09)
      [Abstract] Background: Allograft pathologies, such as valvular, coronary artery, or aortic disease, may occur early and late after cardiac transplantation. Cardiac surgery after heart transplantation (CASH) may be an option ...
    • Individualizing the treatment of patients with heart failure with reduced ejection fraction: a journey from hospitalization to long-term outpatient care 

      Escobar, Carlos; Bonilla-Palomas, Juan Luis; Crespo-Leiro, María Generosa; Esteban-Fernández, Alberto; Farré, Nuria; García, Ana; Núñez, Julio (Taylor & Francis, 2022-08-31)
      [Abstract] Introduction: Despite the relevant advances achieved thanks to the traditional step-by-step therapeutic approach, heart failure with reduced ejection fraction (HFrEF) remains associated with considerable morbidity ...
    • Infectious complications associated with short-term mechanical circulatory support in urgent heart transplant candidates 

      Solla-Buceta, Miguel; González-Vílchez, Francisco; Almenar-Bonet, Luis; Lambert Rodríguez, José Luis; Segovia-Cubero, Javier; González-Costello, José; Delgado-Jiménez, Juan F.; Pérez-Villa, Félix; Crespo-Leiro, María Generosa; Rangel-Sousa, Diego; Martínez-Sellés, Manuel; Rábago, Gregorio; De-la-Fuente Galán, Luis; Blasco-Peiró, Teresa; Hervás-Sotomayor, Daniela; Garrido-Bravo, Iris P.; Mirabet, Sonia; Muñiz, Javier; Barge-Caballero, Eduardo (Elsevier, 2021-02-27)
      [Abstract] Introduction and objectives. Short-term mechanical circulatory support is frequently used as a bridge to heart transplant in Spain. The epidemiology and prognostic impact of infectious complications in these ...
    • International Consortium for Health Outcomes Measurement (ICHOM): standardized patient-centered outcomes measurement set for heart failure patients 

      Burns, Daniel J.P.; Arora, Jason; Okunade, Oluwakemi; Beltrame, John F.; Bernardez-Pereira, Sabrina; Crespo-Leiro, María Generosa; Filippatos, Gerasimos; Hardman, Suzanna; Hoes, Arno W.; Hutchinson, Steven; Jessup, Mariell; Kinsella, Tina; Knapton, Michael; Lam, Carolyn S.P.; Masoudi, Frederick A.; McIntyre, Hugh; Mindham, Richard; Morgan, Louise; Otterspoor, Luuk; Parker, Victoria; Peerson, Hans E.; Pinnock, Claude; Reid, Christopher M.; Riley, Jillian; Stevenson, Lynne W.; McDonagh, Theresa A. (American College of Cardiology Foundation, 2020-03)
      [Abstract] Whereas multiple national, international, and trial registries for heart failure have been created, international standards for clinical assessment and outcome measurement do not currently exist. The working ...
    • In‐hospital and 1‐year mortality associated with diabetes in patients with acute heart failure: results from the ESC‐HFA Heart Failure Long‐Term Registry 

      Targher, Giovanni; Dauriz, Marco; Laroche, Cecile; Temporelli, Pier Luigi; Hassanein, Mahmoud; Seferovic, Petar M.; Drozdz, Jaroslaw; Ferrari, Roberto; Anker, Stefan; Coats, Andrew; Filippatos, Gerasimos; Crespo-Leiro, María Generosa; Mebazaa, Alexandre; Piepoli, Massimo F.; Maggioni, Aldo P.; Tavazzi, Luigi (Wiley, 2016-10-28)
      [Abstract] AIMS: The aim of this study was to evaluate the in-hospital and 1-year prognostic impact of diabetes and elevated blood glucose levels at hospital admission in patients with acute heart failure (HF). METHODS ...
    • Is Becker dystrophinopathy a contraindication to heart transplant?: experience in a single institution 

      Ascencio-Lemus, Marisol Guadalupe; Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Crespo-Leiro, María Generosa (Elsevier, 2018-07-17)
    • Is degree of chronic illness management in heart transplant centers associated with better patient survival?: findings from the intercontinental BRIGHT study 

      Cajita, Maan Isabella; Denhaerynck, Kris; Berben, Lut; Dobbels, Fabienne; Van Cleemput, Johan; Crespo-Leiro, María Generosa; Van Keer, Jan; Poncelet, Alain Jean; Russell, Cynthia; De Geest, Sabina (SAGE, 2021-09-22)
      [Abstract] Purpose: To explore the association between the degree of Chronic illness management and survival rates at 1-, 3-, 5-years post heart transplantation. Methods: Exploratory secondary analysis of a cross-sectional, ...
    • Is heart failure misdiagnosed in hospitalized patients with preserved ejection fraction? From the European Society of Cardiology - Heart Failure Association EURObservational Research Programme Heart Failure Long-Term Registry 

      Kapłon-Cieślicka, Agnieszka; Laroche, Cécile; Crespo-Leiro, María Generosa; Coats, Andrew J.S.; Anker, Stefan; Filippatos, Gerasimos; Maggioni, Aldo P.; Hage, Camilla; Lara-Padrón, Antonio; Fucili, Alessandro; Drożdż, Jarosław; Seferovic, Petar M.; Rosano, Giuseppe; Mebazaa, Alexandre; McDonagh, Theresa A.; Lainscak, Mitja; Ruschitzka, Frank; Lund, Lars H. (Wiley Online Library, 2020-07-02)
      [Abstract] Aims. In hospitalized patients with a clinical diagnosis of acute heart failure (HF) with preserved ejection fraction (HFpEF), the aims of this study were (i) to assess the proportion meeting the 2016 European ...
    • Ischemic cardiomyopathy versus non-ischemic dilated cardiomyopathy in patients with reduced ejection fraction-clinical characteristics and prognosis depending on heart failure etiology (data from European Society of Cardiology heart failure registries) 

      Tyminska, Agata; Ozieranski, Krzysztof; Balsam, Pawel; Maciejewski, Cezary; Wancerz, Anna; Brociek, Emil; Marchel, Michal; Crespo-Leiro, María Generosa; Maggioni, Aldo P.; Drozdz, Jaroslaw; Opolski, Grzegorz; Grabowski, Marcin; Kapłon-Cieslicka, Agnieszka (MDPI, 2022-02-21)
      [Abstract] Personalized management involving heart failure (HF) etiology is crucial for better prognoses for HF patients. This study aimed to compare patients with ischemic cardiomyopathy (ICM) and patients with non-ischemic ...
    • Levosimendan Efficacy and Safety: 20 Years of SIMDAX in Clinical Use 

      Papp, Zoltán; Álvarez, Julián; Bettex, Dominique; Bouchez, Stefan; Brito, Dulce; Černý, Vladimir; Comin-Colet; Comin-Colet, Josep; Crespo-Leiro, María Generosa; Delgado-Jiménez, Juan F.; Édes, István; Eremenko, Alexander; Farmakis, Dimitrios; Fedele, Francesco; Fonseca, Candida; Fruhwald, Sonja; Girardis, Massimo; Guarracino, Fabio; Harjola, Veli-Pekka; Heringlake, Matthias; Herpain, Antoine; Heunks, Leo; Husebye, Tryggve; Ivancan, Višnja; Karason, Kristjan; Kaul, Sundeep; Kivikko, Matti; Kubica, Janek; Masip, Josep; Matskeplishvili, Simon; Mebazaa, Alexandre; Nieminen, Markku S.; Oliva, Fabrizio; Papp, Julius G.; Parissis, John; Parkhomenko, Alexander; Põder, Pentti; Pölzl, Gerhard; Reinecke, Alexander; Ricksten, Sven-Erik; Riha, Hynek; Rudiger, Alain; Sarapohja, Toni; Schwinger, Robert H. G.; Toller, Wolfgang; Tritapepe, Luigi; Tschöpe, Carsten; Wikström, Gerhard; Lewinski, Dirk von; Vrtovec, Bojan; Pollesello, Piero; Agostoni, Piergiuseppe (Wolters Kluwer, 2020-07)
      [Abstract] Levosimendan was first approved for clinical use in 2000, when authorization was granted by Swedish regulatory authorities for the hemodynamic stabilization of patients with acutely decompensated chronic heart ...
    • Light Chain and Transthyretin Cardiac Amyloidosis: Clinical Characteristics, Natural History and Prognostic Factors 

      Barge-Caballero, Gonzalo; Vázquez-García, Raquel; Barge-Caballero, Eduardo; Couto-Mallón, David; Paniagua-Martín, María J.; Barriales-Villa, Roberto; Piñón-Esteban, Pablo; Bouzas-Mosquera, Alberto; Pombo-Otero, Jorge; Debén-Ariznavarreta, Guillermo; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2021-03-13)
      [Abstract] Introduction and objectives. Light-chain amyloidosis (AL-CA) and transthyretin amyloidosis (ATTR-CA) are the most common types of cardiac amyloidosis (CA). We sought to study the clinical characteristics and ...
    • Malignancy following heart transplantation: differences in incidence and prognosis between sexes – a multicenter cohort study 

      Minguito‐Carazo, Carlos; Gómez-Bueno, Manuel; Almenar‐Bonet, Luis; Barge-Caballero, Eduardo; González-Vílchez, Francisco; Delgado-Jiménez, Juan F.; Arizón-del-Prado, José M.; Sousa-Casasnovas, Iago; Mirabet, Sonia; González-Costello, José; Sobrino-Márquez, José Manuel; Pérez-Villa, Félix; Díaz Molina, Beatriz; Rábago, Gregorio; Blasco-Peiró, Teresa; De la Fuente-Galán, Luis; Garrido-Bravo, Iris P.; García-Guereta, Luis; Camino, Manuela; Albert-Brotons, Dimpna C.; Muñiz, Javier; Crespo-Leiro, María Generosa (Wiley Online Library, 2021-01-22)
      [Abstract] Male patients are at increased risk for developing malignancy postheart transplantation (HT); however, real incidence and prognosis in both genders remain unknown. The aim of this study was to assess differences ...