Listar INIBIC-ICATC - Artigos por título
Mostrando ítems 105-124 de 174
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Mitochondrial Pyruvate Carrier Abundance Mediates Pathological Cardiac Hypertrophy
(Springer Nature, 2020-10-26)[Abstract] Cardiomyocytes rely on metabolic substrates, not only to fuel cardiac output, but also for growth and remodelling during stress. Here we show that mitochondrial pyruvate carrier (MPC) abundance mediates ... -
Molecular states associated with dysfunction and graft loss in heart transplants
(Elsevier, 2023-11-30)[Abstract] Background: We explored the changes in gene expression correlating with dysfunction and graft failure in endomyocardial biopsies. Methods: Genome-wide microarrays (19,462 genes) were used to define mRNA ... -
Multi-omics approach reveals prebiotic and potential antioxidant effects of essential oils from the mediterranean diet on cardiometabolic disorder using humanized gnotobiotic mice
(MDPI, 2023-08-20)[Abstract] Essential oils sourced from herbs commonly used in the Mediterranean diet have demonstrated advantageous attributes as nutraceuticals and prebiotics within a model of severe cardiometabolic disorder. The primary ... -
Multilevel factors are associated with immunosuppressant nonadherence in heart transplant recipients: the international BRIGHT study
(Elsevier, 2017-12-05)[Abstract] Factors at the level of family/healthcare worker, organization, and system are neglected in medication nonadherence research in heart transplantation (HTx). The 4-continent, 11-country cross-sectional Building ... -
Omecamtiv mecarbil for patients with severe systolic dysfunction and hypotension
(Oxford Academic, 2022-12-21) -
Omecamtiv Mecarbil in Chronic Heart Failure With Reduced Ejection Fraction: GALACTIC‐HF Baseline Characteristics and Comparison With Contemporary Clinical Trials
(Willey Online Library, 2020-09-20)[Abstract] Aims The safety and efficacy of the novel selective cardiac myosin activator, omecamtiv mecarbil, in patients with heart failure with reduced ejection fraction (HFrEF) is being tested in the Global Approach ... -
Oxygen therapy and palliative care in patients with heart failure. Response
(Elsevier, 2020-05-04) -
Perfiles analíticos pre-configurados en insuficiencia cardiaca: implementación y uso en el Sistema Nacional de Salud Español
(De Gruyter, 2022-03-07)[Resumen] Objetivos. El uso de los perfiles analíticos pre-configurados (PAPs) en el contexto de la insuficiencia cardíaca (IC) podría ayudar a realizar un mejor manejo clínico y gestión eficiente del paciente. Los objetivos ... -
Performance of gene-expression profiling test score variability to predict future clinical events in heart transplant recipients
(BioMed Central, 2015-10-09)[Abstract] Background. A single non-invasive gene expression profiling (GEP) test (AlloMap®) is often used to discriminate if a heart transplant recipient is at a low risk of acute cellular rejection at time of testing. ... -
Performance of prognostic risk scores in chronic heart failure patients enrolled in the European Society of Cardiology Heart Failure long-term registry
(Elsevier, 2018-06)[Abstract] Objectives. This study compared the performance of major heart failure (HF) risk models in predicting mortality and examined their utilization using data from a contemporary multinational registry. Background. ... -
Persistent Pulmonary Hypertension in Corrected Valvular Heart Disease: Hemodynamic Insights and Long‐Term Survival
(Willey, 2021-01-19)[Abstract] Background. The determinants and consequences of pulmonary hypertension after successfully corrected valvular heart disease remain poorly understood. We aim to clarify the hemodynamic bases and risk factors for ... -
Polymorphisms in genes related to the complement system and antibody-mediated cardiac allograft rejection
(Elsevier, 2017-07-15)[Abstract] Background. Heart transplantation (HT) is a life-saving treatment for patients with end-stage heart failure. One of the main problems after HT is the humoral response termed antibody-mediated rejection (AMR). ... -
Popeye's sign, heart disease, and amyloidosis
(Elsevier, 2019-02-21) -
POT1 and damage response malfunction trigger acquisition of somatic activating mutations in the VEGF pathway in cardiac angiosarcomas
(American Heart Association, 2019-09-17)[Abstract] Background Mutations in the POT1 gene explain abnormally long telomeres and multiple tumors including cardiac angiosarcomas (CAS). However, the link between long telomeres and tumorigenesis is poorly ... -
Preoperative toxoplasma gondii serostatus does not affect long-term survival of cardiac transplant recipients: analysis of the Spanish Heart Transplantation Registry
(Elsevier, 2017-10-07)[Abstract] Background. It's unclear whether pre-transplant T. gondii seropositivity is associated with impaired survival in heart transplant recipients. Objectives. To test the above-mentioned hypothesis in the Spanish ... -
Prevalence and correlates of cost-related medication nonadherence to immunosuppressive drugs after heart transplantation: the international multicenter cross-sectional bright study
(Wolters Kluwer, 2020)[Abstract] Background: Cost-related medication nonadherence (CRMNA) refers to not taking medications as prescribed because of difficulties paying for them. Objectives: The aims of this study were (1) to assess the ... -
Prevalence of tricuspid regurgitation after orthotopic heart transplantation and its evolution in the follow-up period: a long-term study
(Elsevier, 2022-10-26)[Abstract] Background. Tricuspid regurgitation (TR) after heart transplant (HT) can be an important complication depending on its etiology and severity. This study aims to analyze the prevalence of TR, the causes, and its ... -
Prevalence, characteristics and prognostic impact of aortic valve disease in patients with heart failure and reduced, mildly reduced, and preserved ejection fraction: an analysis of the ESC Heart Failure Long-Term Registry
(Wiley, 2023-05-21)[Abstract] Aims: To assess the prevalence, clinical characteristics, and outcomes of patients with heart failure (HF) with or without moderate to severe aortic valve disease (AVD) (aortic stenosis [AS], aortic regurgitation ...