• Leukocyte telomere length in patients with radiographic knee osteoarthritis 

  Mosquera, Alejandro; Rego-Pérez, Ignacio; Blanco García, Francisco J; Fernández, José Luis (Wiley, 2019-11-29)

  [Abstract] Relative mean telomere sequence amount was determined by quantitative PCR (qPCR) of peripheral blood leukocyte (PBL) samples obtained at recruitment (n = 310) from individuals from the Osteoarthritis (OA) ...

• Type 1 Diabetes Mellitus reversal via implantation of magnetically purified microencapsulated pseudoislets 

  Espona-Noguera, A.; Etxebarría-Elezgarai, J.; Sáenz del Burgo, L.; Cañibano-Hernández, A.; Gurruchaga, H.; Blanco García, Francisco J; Orive, G.; Hernández, Rosa M.; Benito-López, F.; Ciriza, J.; Basabe-Desmonts, L.; Pedraz, J.L. (Elsevier, 2019-02-10)

  [Abstract] Microencapsulation of pancreatic islets for the treatment of Type I Diabetes Mellitus (T1DM) generates a high quantity of empty microcapsules, resulting in high therapeutic graft volumes that can enhance the ...

• Wnt and RUNX2 mediate cartilage breakdown by osteoarthritis synovial fibroblast‐derived ADAMTS‐7 and ‐12 

  Pérez-García, Selene; Carrión, Mar; Villanueva-Romero, Raúl; Hermida Gómez, Tamara; Fernández-Moreno, Mercedes; Mellado, Mario; Blanco García, Francisco J; Juarranz, Yasmina; Gomariz, Rosa P. (Wiley, 2019-03-22)

  [Abstract] Failure of therapeutic approaches for the treatment of osteoarthritis (OA) based on the inhibition of metalloproteinases, might be because of their constitutive expression in homeostasis, together with their ...

• Hydrogen sulfide and inflammatory joint diseases 

  Burguera, E.F.; Meijide-Failde, Rosa; Blanco García, Francisco J (Bentham, 2017)

  [Abstract] Background: Rheumatoid arthritis (RA) and osteoarthritis (OA) are widespread rheumatic diseases characterized by persistent inflammation and joint destruction. Hydrogen sulfide (H2S) is an endogenous gas with ...

• Induced pluripotent stem cells for cartilage repair: current status and future perspectives 

  Castro Viñuelas, Rocío; Sanjurjo-Rodríguez, Clara; Piñeiro-Ramil, María; Hermida Gómez, Tamara; Fuentes Boquete, Isaac Manuel; Toro Santos, Francisco Javier de; Blanco García, Francisco J; Díaz Prado, Silvia (AO Research Institute Davos, 2018-09-11)

  [Abstract] The establishment of cartilage regenerative medicine is an important clinical issue, but the search for cell sources able to restore cartilage integrity proves to be challenging. Human mesenchymal stromal cells ...

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