Reumatoloxía
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Etanercept withdrawal and retreatment in nonradiographic axial spondyloarthritis: results of RE-EMBARK, an open-label phase IV trial
(Journal of Rheumatology Publishing, 2023-04)[Abstract] Objective: RE-EMBARK investigated etanercept (ETN) withdrawal and retreatment in patients with nonradiographic axial spondyloarthritis (nr-axSpA) achieving inactive disease. Methods: Patients received ETN and ... -
Characteristics and survival of patients with acute traumatic spinal cord injury above T6 with prolonged intensive care unit stays
(Elsevier, 2021-08)[Abstract] Objective: To characterize patients with acute traumatic spinal cord injury (ATSCI) above T6 who were admitted to the intensive care unit (ICU) for ≥30 days and their 1-year mortality compared with patients ... -
Organ dysfunction as determined by the SOFA score is associated with prognosis in patients with acute traumatic spinal cord injury above T6
(Nature, 2021-08-30)[Abstract] Study design: This is a retrospective, observational study. Objectives: To evaluate organ dysfunction in patients with an acute traumatic spinal cord injury (ATSCI) above T6 using the Sequential Organ Failure ... -
Meta-analysis of erosive hand osteoarthritis identifies four common variants that associate with relatively large effect
(BMJ, 2023-03-17)[Abstract] Objectives: Erosive hand osteoarthritis (EHOA) is a severe subset of hand osteoarthritis (OA). It is unclear if EHOA is genetically different from other forms of OA. Sequence variants at ten loci have been ... -
Defective chaperone-mediated autophagy is a hallmark of joint disease in patients with knee osteoarthritis
(Elsevier, 2023-03-08)[Abstract] Objective: Defects in autophagy contribute to joint aging and Osteoarthritis (OA). Identifying specific autophagy types could be useful for developing novel treatments for OA. Design: An autophagy-related ...