• Etanercept withdrawal and retreatment in nonradiographic axial spondyloarthritis: results of RE-EMBARK, an open-label phase IV trial 

  Van den Bosch, Filip; Wei, James Cheng-Chung; Nash, Peter; Blanco García, Francisco J; Graham, Daniela; Zang, Chuanbo; Arthur, Edmund; Borlenghi, Cecilia; Tsekouras, Vassilis; Vlahos, Bonnie; Deodhar, Atul (Journal of Rheumatology Publishing, 2023-04)

  [Abstract] Objective: RE-EMBARK investigated etanercept (ETN) withdrawal and retreatment in patients with nonradiographic axial spondyloarthritis (nr-axSpA) achieving inactive disease. Methods: Patients received ETN and ...

• Characteristics and survival of patients with acute traumatic spinal cord injury above T6 with prolonged intensive care unit stays 

  Esmorís-Arijón, Inés; Galeiras, Rita; Salvador de la Barrera, Sebastián; Mourelo-Fariña, Mónica; Pértega-Díaz, Sonia (Elsevier, 2021-08)

  [Abstract] Objective: To characterize patients with acute traumatic spinal cord injury (ATSCI) above T6 who were admitted to the intensive care unit (ICU) for ≥30 days and their 1-year mortality compared with patients ...

• Organ dysfunction as determined by the SOFA score is associated with prognosis in patients with acute traumatic spinal cord injury above T6 

  Esmorís, Inés; Galeiras, Rita; Montoto Marqués, Antonio; Pértega-Díaz, Sonia (Nature, 2021-08-30)

  [Abstract] Study design: This is a retrospective, observational study. Objectives: To evaluate organ dysfunction in patients with an acute traumatic spinal cord injury (ATSCI) above T6 using the Sequential Organ Failure ...

• Meta-analysis of erosive hand osteoarthritis identifies four common variants that associate with relatively large effect 

  Styrkarsdottir, Unnur; Stefansdottir, Lilja; Thorleifsson, Gudmar; Stefansson, Olafur A.; Saevarsdottir, Saedis; Lund, Sigrun H.; Rafnar, Thorunn; Hoshijima, Kazuyuki; Novak, Kendra; Oreiro, Natividad; Rego-Pérez, Ignacio; Hansen, Channing; Kazmers, Nikolas; Kiemeney, Lambertus A.; Blanco García, Francisco J; Barker, Tyler; Kloppenburg, Margreet; Jurynec, Michel J.; Gudbjartsson, Daniel F.; Jonsson, Helgi; Thorsteinsdottir, Unnur; Stefansson, Kari (BMJ, 2023-03-17)

  [Abstract] Objectives: Erosive hand osteoarthritis (EHOA) is a severe subset of hand osteoarthritis (OA). It is unclear if EHOA is genetically different from other forms of OA. Sequence variants at ten loci have been ...

• Defective chaperone-mediated autophagy is a hallmark of joint disease in patients with knee osteoarthritis 

  Lorenzo-Gómez, I.; Nogueira Recalde, Uxía; García-Domínguez, C.; Oreiro, Natividad; Lotz, Martin; Pinto-Tasende, José A.; Blanco García, Francisco J; Caramés, Beatriz (Elsevier, 2023-03-08)

  [Abstract] Objective: Defects in autophagy contribute to joint aging and Osteoarthritis (OA). Identifying specific autophagy types could be useful for developing novel treatments for OA. Design: An autophagy-related ...

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