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Characterization and miRNA profiling of extracellular vesicles from human osteoarthritic subchondral bone multipotential stromal cells (MSCs)
(Hindawi, 2021-10-09)
[Abstract] Osteoarthritis (OA) is a heterogeneous disease in which the cross-talk between the cells from different tissues within the joint is affected as the disease progresses. Extracellular vesicles (EVs) are known to ...
Current Development of Alternative Treatments for Endothelial Decompensation: Cell-Based Therapy
(Elsevier, 2021-04-01)
[Abstract]
Current treatment for corneal endothelial dysfunction consists in the replacement of corneal endothelium by keratoplasty. Owing to the scarcity of donor corneas and the increasing number of transplants, alternative ...
Generation of mesenchymal cell lines derived from aged donors
(MDPI, 2021-10-01)
[Abstract] Background: Mesenchymal stromal cells (MSCs) have the capacity for self-renewal and multi-differentiation, and for this reason they are considered a potential cellular source in regenerative medicine of cartilage ...
Tips and Tricks for Successfully Culturing and Adapting Human Induced Pluripotent Stem Cells [Protocol]
(Cell Press, 2021-12)
[Abstract] Reprogramming somatic cells toward pluripotency became possible over a decade ago. Since then, induced pluripotent stem cells (iPSCs) have served as a versatile and powerful tool not only for basic research but ...
Analysis of Cryopreservation Protocols and Their Harmful Effects on the Endothelial Integrity of Human Corneas
(MDPI, 2021-11-22)
[Abstract] Corneal cryopreservation can partially solve the worldwide concern regarding donor cornea shortage for keratoplasties. In this study, human corneas were cryopreserved using two standard cryopreservation protocols ...