• Hydrogen sulfide and inflammatory joint diseases 

  Burguera, E.F.; Meijide-Failde, Rosa; Blanco García, Francisco J (Bentham, 2017)

  [Abstract] Background: Rheumatoid arthritis (RA) and osteoarthritis (OA) are widespread rheumatic diseases characterized by persistent inflammation and joint destruction. Hydrogen sulfide (H2S) is an endogenous gas with ...

• Next-generation sequencing and quantitative proteomics of Hutchinson-Gilford progeria syndrome-derived cells point to a role of nucleotide metabolism in premature aging 

  Mateos, Jesús; Fafián Labora, Juan Antonio; Morente-López, Miriam; Lesende-Rodríguez, Iván; Monserrat Iglesias, Lorenzo; Ódena, María A.; Oliveira, Eliandre de; Toro Santos, Francisco Javier de; Arufe, María C. (PLOS, 2018-10-31)

  [Abstract] Hutchinson-Gilford progeria syndrome (HGPS) is a very rare fatal disease characterized for accelerated aging. Although the causal agent, a point mutation in LMNA gene, was identified more than a decade ago, the ...

• Induced pluripotent stem cells for cartilage repair: current status and future perspectives 

  Castro Viñuelas, Rocío; Sanjurjo-Rodríguez, Clara; Piñeiro-Ramil, María; Hermida Gómez, Tamara; Fuentes Boquete, Isaac Manuel; Toro Santos, Francisco Javier de; Blanco García, Francisco J; Díaz Prado, Silvia (AO Research Institute Davos, 2018-09-11)

  [Abstract] The establishment of cartilage regenerative medicine is an important clinical issue, but the search for cell sources able to restore cartilage integrity proves to be challenging. Human mesenchymal stromal cells ...

• Biodistribution and immunogenicity of allogeneic mesenchymal stem cells in a rat model of intraarticular chondrocyte xenotransplantation 

  Marquina, Maribel; Collado, Javier A.; Pérez-Cruz, Magdiel; Fernández-Pernas, Pablo; Fafián Labora, Juan Antonio; Blanco García, Francisco J; Máñez, Rafael; Arufe, María C.; Costa, Cristina (Frontiers, 2017-11-06)

  [Abstract] Xenogeneic chondrocytes and allogeneic mesenchymal stem cells (MSC) are considered a potential source of cells for articular cartilage repair. We here assessed the immune response triggered by xenogeneic ...

• Identification of patients at risk of non-adherence to oral antirheumatic drugs in rheumatoid arthritis using the Compliance Questionnaire in Rheumatology: an ARCO sub-study 

  Marras, Carlos; Monteagudo, Indalecio; Salvador, Georgina; Toro Santos, Francisco Javier de; Escudero, Alejandro; Alegre-Sancho, Juan J.; Raya, Enrique; Ortiz, Ana; Carmona, Loreto; Mestre, Yvonne; Cea-Calvo, Luis; Calvo-Alén, Jaime (Springer, 2017-05-17)

  [Abstract] The ARCO study (Study on Adherence of Rheumatoid Arthritis patients to SubCutaneous and Oral Drugs), a multicenter, non-interventional retrospective study, was primarily designed to assess the percentage of ...

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