Listar GI-TCMR - Artigos por título
Mostrando ítems 114-130 de 130
-
The Experience With Health Care of Patients With Inflammatory Arthritis: A Cross-sectional Survey Using the Instrument to Evaluate the Experience of Patients With Chronic Diseases
(Wolters Kluwer, 2021-01-27)[Abstract] Background: Patients' experience with health care is becoming a key component for the provision of a patient-centered health care model. The aim of this study was to assess the experience with health care of ... -
The mitochondrial inhibitor oligomycin induces an inflammatory response in the rat knee joint
(BioMed Central, 2017-06-12)[Abstract] Background. Recent findings support a connection between mitochondrial dysfunction and activation of inflammatory pathways in articular cells. This study investigates in vivo in an acute model whether ... -
The nuclear factor-erythroid 2-related factor/heme oxygenase-1 axis is critical for the inflammatory features of type 2 diabetes–associated osteoarthritis
(American Society for Biochemistry and Molecular Biology, 2017-07-06)[Asbtract] Epidemiological findings support the hypothesis that type 2 diabetes mellitus (T2DM) is a risk factor for osteoarthritis (OA). Moreover, OA cartilage from patients with T2DM exhibits a greater response to ... -
Therapeutic characteristics of Galician mineral and thermal waters (NW-Spain) ascribed to their local/regional geological setting
(Springer, 2017-03-06)[Abstract] Galicia is located in the NW corner of the Iberian Peninsula (Spain). From a geological point of view, the territory belongs to the Hercynian chain and, more specifically, to a large outcrop dominated by igneous ... -
Therapeutic Delivery of rAAV sox9 via Polymeric Micelles Counteracts the Effects of Osteoarthritis-Associated Inflammatory Cytokines in Human Articular Chondrocytes
(MDPI, 2020-06-25)[Abstract] Osteoarthritis (OA) is a prevalent joint disease linked to the irreversible degradation of key extracellular cartilage matrix (ECM) components (proteoglycans, type-II collagen) by proteolytic enzymes due to an ... -
Therapeutic effects of rAAV-mediated concomittant gene transfer and overexpression of TGF-β and IGF-I on the chondrogenesis of human bone-marrow-derived mesenchymal stem cells
(MDPI, 2019-05-27)[Abstract] Application of chondroreparative gene vectors in cartilage defects is a powerful approach to directly stimulate the regenerative activities of bone-marrow-derived mesenchymal stem cells (MSCs) that repopulate ... -
Therapeutic Potential for Regulation of the Nuclear Factor Kappa-B Transcription Factor p65 to Prevent Cellular Senescence and Activation of Pro-Inflammatory in Mesenchymal Stem Cells
(MDPI, 2021-03-25)[Abstract] Mesenchymal stem cells have an important potential in the treatment of age-related diseases. In the last years, small extracellular vesicles derived from these stem cells have been proposed as cell-free ... -
Therapy free of cells vs human mesenchymal stem cells from umbilical cord stroma to treat the inflammation in OA
(Springer, 2022-10-20)[Abstract] Osteoarthritis (OA) is closely linked to the increase in the number of senescent cells in joint tissues, and the senescence-associated secretory phenotype (SASP) is implicated in cartilage degradation. In the ... -
There is something you must see: breaking down the remission concept in rheumatoid arthritis from a rheumatologist's perspective
(Clinical and Experimental Rheumatology, 2020-01)[Abstract] Objectives: To explore the remission concept in rheumatoid arthritis (RA) and the implications of the existing definitions when applied to clinical practice among rheumatologists with different profiles. Methods: ... -
Tips and tricks for successfully culturing and adapting human induced pluripotent stem cells
(Cell Press, 2021-12)[Abstract] Reprogramming somatic cells toward pluripotency became possible over a decade ago. Since then, induced pluripotent stem cells (iPSCs) have served as a versatile and powerful tool not only for basic research but ... -
Tissue array analysis for the differentiation of gliosis from gliomas
(Spandidos, 2011-03-22)[Abstract] The aim of this study was to provide a methodology to make a clear distinction between malignant tumors and morphologically similar benign processes, by examining the expression of EGFR, VEGF, HIF1-α, survivin, ... -
Tratamiento de lesiones del cartílago articular con terapia celular
(Elsevier, 2008-11-13)[Resumen] Las lesiones del cartílago articular que no afectan a la integridad del hueso subcondral no se reparan espontáneamente. El carácter asintomático de estas lesiones propicia la progresiva degeneración articular y ... -
Umbilical Cord as a Mesenchymal Stem Cell Source for Treating Joint Pathologies
(Baishideng, 2011-06-18)[Abstract] Articular cartilage disorders and injuries often result in life-long chronic pain and compromised quality of life. Regrettably, the regeneration of articular cartilage is a continuing challenge for biomedical ... -
Usefulness of mesenchymal cell lines for bone and cartilage regeneration research
(MDPI, 2019-12-13)[Abstract] The unavailability of sufficient numbers of human primary cells is a major roadblock for in vitro repair of bone and/or cartilage, and for performing disease modelling experiments. Immortalized mesenchymal ... -
Valor pronóstico de la resonancia magnética precoz en la morbilidad y mortalidad de la lesión medular traumática
(Elsevier, 2022-02-12)[Resumen] Objetivo. Valorar en individuos con lesión medular traumática (LMT) la relación entre la mortalidad y la necesidad de UCI y las alteraciones objetivadas mediante resonancia magnética (RM) precoz, analizando ... -
Versatility of induced Pluripotent Stem Cells (iPSCs) for improving the knowledge on musculoskeletal diseases
(MDPI, 2020-08-25)[Abstract] Induced pluripotent stem cells (iPSCs) represent an unlimited source of pluripotent cells capable of di erentiating into any cell type of the body. Several studies have demonstrated the valuable use of iPSCs ... -
Wnt signalling and cancer stem cells
(Springer, 2009-07-15)[Abstract] Intracellular signalling mediated by secreted Wnt proteins is essential for the establishment of cell fates and proper tissue patterning during embryo development and for the regulation of tissue homeostasis and ...