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Translation of clinical problems in osteoarthritis into pathophysiological research goals
dc.contributor.author | van der Kraan, Peter M. | |
dc.contributor.author | Berenbaum, Francis | |
dc.contributor.author | Blanco García, Francisco J | |
dc.contributor.author | De Bari, Cosimo | |
dc.contributor.author | Lafeber, Floris | |
dc.contributor.author | Hauge, Ellen | |
dc.contributor.author | Higginbottom, Adele | |
dc.contributor.author | Ioan-Facsinay, Andreea | |
dc.contributor.author | Loughlin, John | |
dc.contributor.author | Meulenbelt, Ingrid | |
dc.contributor.author | Moilanen, Eeva | |
dc.contributor.author | Pitsilidou, Irene | |
dc.contributor.author | Tsezou, Aspasia | |
dc.contributor.author | van Meurs, Joyce | |
dc.contributor.author | Vincent, Tonia | |
dc.contributor.author | Wittoek, Ruth | |
dc.contributor.author | Lories, Rik | |
dc.date.accessioned | 2020-03-31T08:19:01Z | |
dc.date.available | 2020-03-31T08:19:01Z | |
dc.date.issued | 2016-05-26 | |
dc.identifier.citation | van der Kraan PM, Berenbaum F, Blanco FJ, Cosimo de B, Lafeber F, Hauge E, Higginbottom A, Ioan-Facsinay A, Loughlin J, Meulenbelt I, Moilanen E, Pitsillidou I, Tsezou A, van Meurs J, Vincent T, Wittoek R, Lories R; EULAR Study group in OA (http://www.eular.org/investigative_rheumatology_study_groups.cfm). Translation of clinical problems in osteoarthritis into pathophysiological research goals. RMD Open. 2016 May 26;2(1):e000224. | es_ES |
dc.identifier.issn | 2056-5933 | |
dc.identifier.uri | http://hdl.handle.net/2183/25272 | |
dc.description.abstract | [Abstract] Osteoarthritis (OA) accounts for more disability among the elderly than any other disease and is associated with an increased mortality rate. The prevalence in Europe will rise in the future since this continent has a strongly ageing population and an obesity epidemic; obesity and age both being major risk factors for OA. No adequate therapeutic options, besides joint replacement, are available, although they are greatly needed and should be acquired by adequate research investments. However, the perspective on OA from a researcher's point of view is not always aligned with the perspective of a patient with OA. Researchers base their views on OA mainly on abnormalities in structure and function while patients consider OA as a collection of symptoms. In this viewpoint paper, we discuss the possibility of translating the most important clinical problems into pathophysiological research goals to facilitate the translation from bench to bedside and vice versa. This viewpoint is the outcome of a dialogue within the ‘European League Against Rheumatism study group on OA’ and People with Arthritis/Rheumatism across Europe (PARE) representatives. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | BMJ | es_ES |
dc.relation.uri | http://dx.doi.org/10.1136/rmdopen-2015-000224 | es_ES |
dc.rights | Creative Commons Attribution-NonCommercial 4.0 International License (CC-BY-NC 4.0) | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | * |
dc.subject | Osteoarthritis | es_ES |
dc.subject | Patient perspective | es_ES |
dc.subject | Qualitative research | es_ES |
dc.subject | Synovitis | es_ES |
dc.title | Translation of clinical problems in osteoarthritis into pathophysiological research goals | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.access | info:eu-repo/semantics/openAccess | es_ES |
UDC.journalTitle | Rheumatic & Musculoskeletal Diseases | es_ES |
UDC.volume | 2 | es_ES |
UDC.issue | 1 | es_ES |
UDC.startPage | e000224 | es_ES |
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