INIBIC- REUMA - Artigos: Envíos recentes

Mostrando ítems 46-50 de 184

    • Mitochondrial biogenesis: a potential therapeutic target for osteoarthritis 

      Blanco García, Francisco J; Fernández-Moreno, Mercedes (Elsevier, 2020-05-14)
      [Abstract] Mitochondrial dysfunction of human articular chondrocytes is considered a hallmark of cartilage degradation and OA pathogenesis. Due to the huge number of cellular processes in which mitochondria is implicated, ...

    • Design of a digital-PCR assay to quantify fragmented human mitochondrial DNA 

      Mosquera, Alejandro; Guillén, Rebeca; Otero, Fátima; Rego-Pérez, Ignacio; Blanco García, Francisco J; Fernández, José Luis (Wiley, 2021-06-11)
      [Abstract] Digital PCR (dPCR) has been adapted to quantify the proportion of mitochondrial DNA (mtDNA) molecules without and with double-strand DNA breaks (DSBs). This is based on a break-apart approach of two differentially ...

    • Core outcome measurement instrument selection for physical function in hand osteoarthritis using the OMERACT Filter 2.1 process 

      Kroon, Féline P.B.; van der Heijde, Désirée; Maxwell, Lara J.; Beaton, Dorcas E.; Abishek, Abishek; Berenbaum, Francis; Blanco García, Francisco J; Conaghan, Philip G.; Dziedzic, Krysia; Hill, Catherine L.; Haugen, Ida K.; Ishimori, Mariko; Ritschl, Valentin; Stamm, Tanja A.; Wittoek, Ruth; Kopplenburg, Margreet (Elsevier, 2021-12)
      [Abstract] Objective: Physical function is one of the Outcome Measures in Rheumatology (OMERACT) core outcome domains for hand osteoarthritis studies. Our aim was to select appropriate instrument(s) to measure this domain, ...

    • Molecular analysis of the destruction of articular joint tissues by Raman spectroscopy 

      Casal-Beiroa, Paula; González, Pío; Blanco García, Francisco J; Magalhäes, Joana (Taylor & Francis, 2020-06-30)
      [Abstract] Introduction: Osteoarthritis (OA) is a highly heterogenous disease influenced by different molecular, anatomic, and physiologic imbalances. Some of the bottlenecks for enhanced diagnosis and therapeutic assessment ...

    • Prevalence of symptomatic axial osteoarthritis phenotypes in Spain and associated socio-demographic, anthropometric, and lifestyle variables 

      Silva-Díaz, María T.; Blanco García, Francisco J; Quevedo Vila, Víctor; Seoane-Mato, Daniel; Pérez-Ruiz, Fernando; Juan-Mas, Antonio; Pego-Reigosa, José M.; Narváez, Javier; Quilis, Neus; Cortés, Raúl; Romero-Pérez, Antonio; Fábregas Canales, Dolores; Font Gayá, Teresa; Bordoy Ferrer, Carolina; Prado-Galbarro, Francisco Javier; Sánchez-Piedra, Carlos; Díaz-González, Federico; Bustabad-Reyes, Sagrario (Springer, 2021-11-10)
      [Abstract] Objective. Axial osteoarthritis (OA) is a common cause of back and neck pain, however, few studies have examined its prevalence. The aim was to estimate the prevalence and the characteristics of symptomatic axial ...