INIBIC- REUMA - Artigos: Envíos recentes
Mostrando ítems 36-40 de 184
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mtDNA haplogroup A enhances the effect of obesity on the risk of knee OA in a mexican population
(Nature, 2022-03-25)[Abstract] To evaluate the influence of mitochondrial DNA haplogroups on the risk of knee OA in terms of their interaction with obesity, in a population from Mexico. Samples were obtained from (n = 353) knee OA patients ... -
Reduced levels of H₂S in diabetes-associated osteoarthritis are linked to hyperglycaemia, Nrf-2/HO-1 signalling downregulation and chondrocyte dysfunction
(MDPI, 2022-03-25)[Abstract] Different findings indicate that type 2 diabetes is an independent risk factor for osteoarthritis (OA). However, the mechanisms underlying the connection between both diseases remain unclear. Changes in the ... -
GaitSmart motion analysis compared to commonly used function outcome measures in the IMI-APPROACH knee osteoarthritis cohort
(PLoS ONE, 2022-03-23)[Abstract] Background: There are multiple measures for assessment of physical function in knee osteoarthritis (OA), but each has its strengths and limitations. The GaitSmart® system, which uses inertial measurement units ... -
Genetic biomarkers in osteoarthritis: a quick overview
(Faculty Opinions, 2021-11-10)[Abstract] Osteoarthritis (OA) is a chronic musculoskeletal disease with a polygenic and heterogeneous nature. In addition, when clinical manifestations appear, the evolution of the disease is usually already irreversible. ... -
Targeted phospholipidomic analysis of synovial fluid as a tool for osteoarthritis deep phenotyping
(Elsevier, 2021-10-20)[Abstract] Objective. The aim of this study was to carry out a targeted phospholipidomic analysis on synovial fluid (SF) from patients with different grades of osteoarthritis (OA) and controls, in order to search for ...