INIBIC- REUMA - Artigos: Envíos recentes

Mostrando ítems 36-40 de 184

    • mtDNA haplogroup A enhances the effect of obesity on the risk of knee OA in a mexican population 

      Ramos-Louro, Paula; Arellano Pérez Vertti, Rubén Daniel; López Reyes, Alberto; Martínez-Nava, Gabriela Angélica; Espinosa, Rolando; Pineda, Carlos; González-Galarza, Faviel Francisco; Argüello Astorga, Rafael; Aguilar Muñiz, Lizette Sarai; Hernández Terán, Fernando; Parra Torres, Nancy Marbella; Durán Sotuela, Alejandro; Fernández-Moreno, Mercedes; Balboa-Barreiro, Vanesa; Blanco García, Francisco J; Rego-Pérez, Ignacio (Nature, 2022-03-25)
      [Abstract] To evaluate the influence of mitochondrial DNA haplogroups on the risk of knee OA in terms of their interaction with obesity, in a population from Mexico. Samples were obtained from (n = 353) knee OA patients ...

    • Reduced levels of H₂S in diabetes-associated osteoarthritis are linked to hyperglycaemia, Nrf-2/HO-1 signalling downregulation and chondrocyte dysfunction 

      Piñeiro-Ramil, María; Burguera, Elena F.; Hermida-Gómez, Tamara; Caramés, Beatriz; Oreiro, Natividad; Meijide-Faílde, Rosa; Blanco García, Francisco J; Vaamonde-García, Carlos (MDPI, 2022-03-25)
      [Abstract] Different findings indicate that type 2 diabetes is an independent risk factor for osteoarthritis (OA). However, the mechanisms underlying the connection between both diseases remain unclear. Changes in the ...

    • GaitSmart motion analysis compared to commonly used function outcome measures in the IMI-APPROACH knee osteoarthritis cohort 

      van Helvoort, Eefje M.; Hodgings, Diana; Mastbergen, Simon; Marijnissen, Anne C.A.; Kloppenburg, Margreet; Blanco García, Francisco J; Haugen, Ida K.; Berenbaum, Francis; Lafeber, Floris P.J.G.; Welsing, Paco M.J. (PLoS ONE, 2022-03-23)
      [Abstract] Background: There are multiple measures for assessment of physical function in knee osteoarthritis (OA), but each has its strengths and limitations. The GaitSmart® system, which uses inertial measurement units ...

    • Genetic biomarkers in osteoarthritis: a quick overview 

      Rego-Pérez, Ignacio; Durán Sotuela, Alejandro; Ramos-Louro, Paula; Blanco García, Francisco J (Faculty Opinions, 2021-11-10)
      [Abstract] Osteoarthritis (OA) is a chronic musculoskeletal disease with a polygenic and heterogeneous nature. In addition, when clinical manifestations appear, the evolution of the disease is usually already irreversible. ...

    • Targeted phospholipidomic analysis of synovial fluid as a tool for osteoarthritis deep phenotyping 

      Rocha Loureda, Beatriz; Illiano, Anna; Calamia, Valentina; Pinto, Gabriella; Amoresano, Angela; Ruiz-Romero, Cristina; Blanco García, Francisco J (Elsevier, 2021-10-20)
      [Abstract] Objective. The aim of this study was to carry out a targeted phospholipidomic analysis on synovial fluid (SF) from patients with different grades of osteoarthritis (OA) and controls, in order to search for ...