• A single nucleotide polymorphism in the Il17ra promoter is associated with functional severity of ankylosing spondylitis 

      Vidal-Castiñeira, José Ramón; López-Vázquez, Antonio; Díaz-Peña, Alberto; Díaz-Bulnes, Paula; Martínez-Camblor, Pablo; Coto, Eliecer; Coto-Segura, Pablo; Bruges-Armas, Jacome; PInto, José Antonio; Blanco García, Francisco J; Sánchez, Alejandra; Mulero, Juan; Queiro, Rubén; López-Larrea, Carlos (PLoS, 2016-07-14)
      [Abstract] The aim of this study was to identify new genetic variants associated with the severity of ankylosing spondylitis (AS). We sequenced the exome of eight patients diagnosed with AS, selected on the basis of the ...
    • Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1 

      Cortes, Adrian; Pulit, Sara L.; Leo, Paul J.; Pointon, Jenny J.; Robinson, Philip C.; Weisman, Michael H.; Ward, Michael; Gensler, Lianne S.; Zhou, Xiaodong; Garchon, Henri-Jean; Chiocchia, Gilles; Nossent, Johannes; Lie, Benedicte A.; Øystein, Førre; Tuomilehto, Jaako; Laiho, Kari; Bradbury, Linda A.; Elewaut, Dirk; Burgos-Vargas, Rubén; Stebbings, Simon; Appleton, Louise; Farrah, Claire; Lau, Jonathan; Haroon, Nigil; Mulero, Juan; Blanco García, Francisco J; González-Gay, Miguel Á.; López-Larrea, Carlos; Bowness, Paul; Gaffney, Karl; Gaston, Hill; Gladman, Dafna D.; Rahman, Proton; Maksymowych, Walter P.; Crusius, Bart A.; van der Horst-Buinsma, Irene E.; Valle-Oñate, Raphael; Romero-Sánchez, Consuelo; Hansen, Inger Myrnes; Pimentel-Santos, Fernando M.; Inman, Robert D.; Martín, Javier; Breban, Maxime; Wordsworth, Bryan Paul; Reveille, John D.; Evans, David M.; Bakker, Paul I.W. de; Brown, Matthew A. (Nature, 2015-05-21)
      [Abstract] Article Open Access Published: 21 May 2015 Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1 Adrian Cortes, Sara L. Pulit, Paul J. ...
    • The phenotype of axial spondyloarthritis: is it dependent on HLA–B27 status? 

      Coates, Laura C.; Baraliakos, Xenofon; Blanco García, Francisco J; Alonso Blanco-Morales, Elena; Braun, Jurgen; Chadran, Vinod; Fernández-Sueiro, José Luis; FitzGerald, Oliver; Gallagher, Phil; Gladman, Dafna D.; Gubar, Elena; Korotaeva, Tatiana; Loginova, Elena; Lubrano, Ennio; Mulero, Juan; Pinto-Tasende, José A.; Queiro, Rubén; Sanz Sanz, Jesús; Szentpetery, Agnes; Helliwell, Philip S. (Wiley, 2020-02-26)
      [Abstract] Objective: To describe the radiographic phenotype of axial spondyloarthritis (SpA) according to the presence of HLA-B27. Methods: An international collaboration compared the radiographic phenotype of axial ...