Listar INIBIC- REUMA - Artigos por autor "Fafián Labora, Juan Antonio"
Mostrando ítems 1-4 de 4
-
3, 3′, 5-triiodo-L-thyronine increases in vitro chondrogenesis of mesenchymal stem cells from human umbilical cord stroma through SRC2
Fernández-Pernas, Pablo; Fafián Labora, Juan Antonio; Lesende-Rodríguez, Iván; Mateos, Jesús; Fuente, Alexandre de la; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J; Arufe, M.C. (Wiley, 2016-07-08)[Abstract] Our group focuses on the study of mesenchymal stem cells (MSCs) from human umbilical cord stroma or Warthońs jelly and their directed differentiation toward chondrocyte-like cells capable of regenerating damaged ... -
Biodistribution and Immunogenicity of Allogeneic Mesenchymal Stem Cells in a Rat Model of Intraarticular Chondrocyte Xenotransplantation
Marquina, Maribel; Collado, Javier A.; Pérez-Cruz, Magdiel; Fernández-Pernas, Pablo; Fafián Labora, Juan Antonio; Blanco García, Francisco J; Máñez, Rafael; Arufe, M.C.; Costa, Cristina (Frontiers, 2017-11-06)[Abstract] Xenogeneic chondrocytes and allogeneic mesenchymal stem cells (MSC) are considered a potential source of cells for articular cartilage repair. We here assessed the immune response triggered by xenogeneic ... -
iTRAQ-Based Analysis of Progerin Expression Reveals Mitochondrial Dysfunction, Reactive Oxygen Species Accumulation and Altered Proteostasis
Mateos, Jesús; Landeira-Abia, Arancha; Fafián Labora, Juan Antonio; Fernández-Pernas, Pablo; Lesende-Rodríguez, Iván; Fernández-Puente, Patricia; Fernández-Moreno, Mercedes; Delmiro, Aitor; Martín, Miguel A.; Blanco García, Francisco J; Arufe, M.C. (BioMed Central, 2015-06-12)[Abstract] Introduction. Nuclear accumulation of a mutant form of the nuclear protein Lamin-A, called Progerin (PG) or Lamin AΔ50, occurs in Hutchinson-Gilford Progeria Syndrome (HGPS) or Progeria, an accelerated aging ... -
Proteomic Applications in the Study of Human Mesenchymal Stem Cells
Mateos, Jesús; Arufe, M.C.; Fernández-Pernas, Pablo; Fafián Labora, Juan Antonio; Blanco García, Francisco J (Multidisciplinary Digital Publishing Institute, 2014-02-07)Mesenchymal stem cells (MSCs) are undifferentiated cells with an unlimited capacity for self-renewal and able to differentiate towards specific lineages under appropriate conditions. MSCs are, a priori, a good target for ...