Listar INIBIC- REUMA - Artigos por título

Mostrando ítems 136-155 de 184

    • Predictors of intensive care unit stay in patients with acute traumatic spinal cord injury above T6 

      Esmorís, Inés; Galeiras, Rita; Ferreiro-Velasco, María Elena; Pértega-Díaz, Sonia (Elsevier, 2022-10)
      [Abstract] Objective: The objective of this study was to identify factors associated with the intensive care unit (ICU) length of stay (LOS) of patients with an acute traumatic spinal cord injury above T6. Methods: We ...

    • Prevalence of hospital PCR-confirmed COVID-19 cases in patients with chronic inflammatory and autoimmune rheumatic diseases 

      Pablos, José L.; Abasolo, Lydia; Álvaro-Gracia, José M.; Blanco García, Francisco J; Blanco, Ricardo; Castrejón, Isabel; Fernández-Fernández, David; Fernández-Gutiérrez, Benjamín; Galindo-Izquierdo, María; González-Gay, Miguel Á.; Manrique-Arija, Sara; Mena Vázquez, Natalia; Mera Varela, Antonio; Retuerto, Miriam; Seijas-López, Álvaro (BMJ, 2020-06-12)
      [Abstract] Background: The susceptibility of patients with rheumatic diseases and the risks or benefits of immunosuppressive therapies for COVID-19 are unknown. Methods: We performed a retrospective study with patients ...

    • Prevalence of symptomatic axial osteoarthritis phenotypes in Spain and associated socio-demographic, anthropometric, and lifestyle variables 

      Silva-Díaz, María T.; Blanco García, Francisco J; Quevedo Vila, Víctor; Seoane-Mato, Daniel; Pérez-Ruiz, Fernando; Juan-Mas, Antonio; Pego-Reigosa, José M.; Narváez, Javier; Quilis, Neus; Cortés, Raúl; Romero-Pérez, Antonio; Fábregas Canales, Dolores; Font Gayá, Teresa; Bordoy Ferrer, Carolina; Prado-Galbarro, Francisco Javier; Sánchez-Piedra, Carlos; Díaz-González, Federico; Bustabad-Reyes, Sagrario (Springer, 2021-11-10)
      [Abstract] Objective. Axial osteoarthritis (OA) is a common cause of back and neck pain, however, few studies have examined its prevalence. The aim was to estimate the prevalence and the characteristics of symptomatic axial ...

    • Prevalence of Systemic Lupus Erythematosus in Spain: Higher than Previously Reported in Other Countries? 

      Cortés Verdú, Raúl; Pego-Reigosa, J.; Seoane-Mato, Daniel; Morcillo Valle, Mercedes; Palma Sánchez, Deseada; Moreno Martínez, María J.; Mayor González, Marta; Atxotegi Sáez de Buruaga, Joana; Urionagüena Onaindia, Irati; Blanco Cáceres, Boris A.; Silva-Fernández, Lucía; Sivera, Francisca; Blanco García, Francisco J; Sánchez-Piedra, Carlos; Díaz-González, Federico; Bustabad, Sagrario (Oxford, 2020-01-30)
      [Abstract] Objectives: Prevalence of SLE varies among studies, being influenced by study design, geographical area and ethnicity. Data about the prevalence of SLE in Spain are scarce. In the EPISER2016 study, promoted by ...

    • Prevalence of Systemic Lupus Erythematosus in Spain: Higher than Previously Reported in other Countries? 

      Cortés Verdú, Raúl; Pego-Reigosa, J.; Seoane-Mato, Daniel; Morcillo Valle, Mercedes; Palma Sánchez, Deseada; Moreno Martínez, María J.; Mayor González, Marta; Atxotegi Sáez de Buruaga, Joana; Urionagüena Onaindia, Irati; Blanco Cáceres, Boris A.; Silva-Fernández, Lucía; Sivera, Francisca; Blanco García, Francisco J; Sánchez-Piedra, Carlos; Díaz-González, Federico; Bustabad, Sagrario (Oxford, 2020-01-30)
      [Abstract] Objectives: Prevalence of SLE varies among studies, being influenced by study design, geographical area and ethnicity. Data about the prevalence of SLE in Spain are scarce. In the EPISER2016 study, promoted by ...

    • Prevalencia de artrosis sintomática en España: estudio EPISER2016 

      Blanco García, Francisco J; Silva-Díaz, María T.; Quevedo Vila, Víctor; Seoane-Mato, Daniel; Pérez Ruiz, Fernando; Juan-Mas, Antonio; Pego-Reigosa, J.; Narváez, Javier; Quilis, Neus; Cortés, Raúl; Romero Pérez, Antonio; Fábregas Canales, Dolores; Font Gayá, Teresa; Bordoy Ferrer, Carolina; Sánchez-Piedra, Carlos; Díaz-González, Federico; Bustabad, Sagrario (Elsevier, 2020-04-28)
      [Resumen] Introducción. La Sociedad Española de Reumatología elaboró en el año 2000 el estudio EPISER2000 para conocer la prevalencia de la artrosis y otras enfermedades reumáticas en España. Los cambios sociodemográficos ...

    • PROCOAC (PROspective COhort of A Coruña) description: spanish prospective cohort to study osteoarthritis 

      Oreiro, Natividad; Raga, Ana C.; Rego-Pérez, Ignacio; Pértega-Díaz, Sonia; Silva-Díaz, Maite; Freire, Mercedes; Fernández-López, Carlos; Blanco García, Francisco J (Elsevier, 2021-05-03)
      [Abstract] Introduction and objective: The use of well characterized osteoarthritis (OA) cohorts is mandatory for the study and knowledge of this disease. Currently, there is no prospective cohort in this pathology in ...

    • Profile of matrix-remodeling proteinases in osteoarthritis: impact of fibronectin 

      Pérez-García, Selene; Carrión, Mar; Gutiérrez-Cañas, Irene; Villanueva-Romero, Raúl; Castro, David; Martínez, Carmen; González-Álvaro, Isidoro; Blanco García, Francisco J; Juarranz, Yasmina; Gomariz, Rosa P. (MDPI, 2019-12-22)
      [Abstract] The extracellular matrix (ECM) is a complex and specialized three-dimensional macromolecular network, present in nearly all tissues, that also interacts with cell surface receptors on joint resident cells. Changes ...

    • Proteome Analysis During Chondrocyte Differentiation in a New Chondrogenesis Model Using Human Umbilical Cord Stroma Mesenchymal Stem Cells 

      Fuente, Alexandre de la; Mateos, Jesús; Lesende-Rodríguez, Iván; Calamia, Valentina; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Arufe, M.C.; Blanco García, Francisco J (American Society for Biochemistry and Molecular Biology, 2011-10-17)
      [Abstract] Umbilical cord stroma mesenchymal stem cells were differentiated toward chondrocyte-like cells using a new in vitro model that consists of the random formation of spheroids in a medium supplemented with fetal ...

    • Proteomic Analysis of Synovial Fibroblasts and Articular Chondrocytes Co-Cultures Reveals Valuable VIP-Modulated Inflammatory and Degradative Proteins in Osteoarthritis 

      Pérez-García, Selene; Calamia, Valentina; Hermida Gómez, Tamara; Gutiérrez-Cañas, Irene; Carrión, Mar; Villanueva-Romero, Raúl; Castro, David; Martínez, Carmen; Juarranz, Yasmina; Blanco García, Francisco J; Gomariz, Rosa P. (MDPI, 2021-06-16)
      [Abstract] Osteoarthritis (OA) is the most common musculoskeletal disorder causing a great disability and a reduction in the quality of life. In OA, articular chondrocytes (AC) and synovial fibroblasts (SF) release ...

    • Proteomic Applications in the Study of Human Mesenchymal Stem Cells 

      Mateos, Jesús; Arufe, M.C.; Fernández-Pernas, Pablo; Fafián Labora, Juan Antonio; Blanco García, Francisco J (Multidisciplinary Digital Publishing Institute, 2014-02-07)
      Mesenchymal stem cells (MSCs) are undifferentiated cells with an unlimited capacity for self-renewal and able to differentiate towards specific lineages under appropriate conditions. MSCs are, a priori, a good target for ...

    • Proteomic profiling of human menisci from mild joint degeneration and end-stage osteoarthritis versus healthy controls 

      Paz-González, Rocío; Turkiewicz, Aleksandra; Ali, Neserin; Ruiz-Romero, Cristina; Blanco García, Francisco J; Englund, Martin; Önnerfjord, Patrik (Elsevier, 2023-12)
      [Abstract] Objective. To gain new insight into the molecular changes of the meniscus by comparing the proteome profiles of healthy controls with mild degeneration and end-stage osteoarthritis (OA). Method. We obtained ...

    • Quantification of cells expressing mesenchymal stem cell markers in healthy and osteoarthritic synovial membranes 

      Hermida Gómez, Tamara; Fuentes Boquete, Isaac Manuel; Gimeno-Longas, María José; Muiños-López, Emma; Díaz-Prado, Silvia; De-Toro, Javier; Blanco García, Francisco J (Journal of Rheumatology Publishing Company, 2010-11-15)
      [Abstract] Objective. To quantify cells expressing mesenchymal stem cell (MSC) markers in synovial mem- branes from human osteoarthritic (OA) and healthy joints. Methods. Synovial membranes from OA and healthy joints were ...

    • Quantitative CT of the knee in the IMI-APPROACH osteoarthritis cohort: Association of bone mineral density with radiographic disease severity, meniscal coverage and meniscal extrusion 

      Heiss, Rafael; Laredo, Jean-Denis; Wirth, Wolfgang; Jansen, Mylène P.; Marijnissen, Anne C.A.; Lafeber, Floris P.J.G.; Lalande, Agnes; Weinans, Harrie H.; Blanco García, Francico J; Berenbaum, Francis; Kloppenburg, Margreet; Haugen, Ida K.; Engelke, Klaus; Roemer, Frank W. (Elsevier, 2023-03)
      [Abstract] Objective: Osteoarthritis (OA) is a highly prevalent chronic condition. The subchondral bone plays an important role in onset and progression of OA making it a potential treatment target for disease-modifying ...

    • Real-world effectiveness and safety of SDZ ETN, an etanercept biosimilar, in patients with rheumatic diseases: final results from multi-country COMPACT study 

      Schmalzing, Marc; Kellner, Herbert; Askari, Ayman; De-Toro, Javier; Vázquez Pérez-Coleman, Julio César; Foti, Rosario; Jeka, Slawomir; Haraoui, Boulos; Allanore, Yannick; Peichl, Peter; Oehri, Martin; Rahman, Masiur; Furlan, Fabricio; Romero, Elisa; Hachaichi, Sohaib; Both, Charlotte; Brueckmann, Ines; Sheeran, Tom (Springer Nature, 2023-11-11)
      [Abstract] Introduction: COMPACT, a non-interventional study, evaluated the persistence, effectiveness, safety and patient-reported outcomes (PROs) in patients with rheumatoid arthritis (RA), axial-spondyloarthritis ...

    • Reduced levels of H₂S in diabetes-associated osteoarthritis are linked to hyperglycaemia, Nrf-2/HO-1 signalling downregulation and chondrocyte dysfunction 

      Piñeiro-Ramil, María; Burguera, Elena F.; Hermida-Gómez, Tamara; Caramés, Beatriz; Oreiro, Natividad; Meijide-Faílde, Rosa; Blanco García, Francisco J; Vaamonde-García, Carlos (MDPI, 2022-03-25)
      [Abstract] Different findings indicate that type 2 diabetes is an independent risk factor for osteoarthritis (OA). However, the mechanisms underlying the connection between both diseases remain unclear. Changes in the ...

    • Relationship Between Motion, Using the GaitSmartTM System, and Radiographic Knee Osteoarthritis: An Explorative Analysis in the IMI-APPROACH Cohort 

      van Helvoort, Eefje M.; Hodgins, Diana; Mastbergen, Simon C.; Marijnissen, Anne Karien; Guehring, Hans; Loef, Marieke; Kloppenburg, Margreet; Blanco García, Francisco J; Haugen, Ida K.; Berenbaum, Francis; Lafeber, Floris; Welsing, Paco M.J. (Oxford, 2020-12-25)
      [Abstract] Objectives: To assess underlying domains measured by GaitSmartTMparameters and whether these are additional to established OA markers including patient reported outcome measures (PROMs) and radiographic parameters, ...

    • Relationship between the dynamics of telomere loss in peripheral blood leukocytes from osteoarthritis patients and mitochondrial DNA haplogroup 

      Guillén, Rebeca; Otero, Fátima; Mosquera, Alejandro; Rego-Pérez, Ignacio; Blanco García, Francisco J; Fernández García, José Luis (The Journal of Rheumatology Publishing, 2021-03-01)
      [Abstract] Objective: To evaluate the evolution of telomere length from peripheral blood leukocytes (PBLs) in subjects from the Osteoarthritis Initiative (OAI) cohort in relation to the incidence of osteoarthritis (OA), ...

    • RGD-Dendrimer-Poly(L-lactic) Acid Nanopatterned Substrates for the Early Chondrogenesis of Human Mesenchymal Stromal Cells Derived from Osteoarthritic and Healthy Donors 

      Rodríguez-Pereira, Cristina; Lagunas, Anna; Casanellas, Ignasi; Vida, Yolanda; Pérez-Inestrosa, Ezequiel; Andrades, José A.; Becerra, José; Samitier, Josep; Blanco García, Francisco J; Magalhaes, Joana (MDPI, 2020-05-13)
      [Abstract] Aiming to address a stable chondrogenesis derived from mesenchymal stromal cells (MSCs) to be applied in cartilage repair strategies at the onset of osteoarthritis (OA), we analyzed the effect of arginine–glyc ...

    • Rheumatoid arthritis response to treatment across IgG1 allotype – anti-TNF incompatibility: a case-only study 

      Montes, Adriana; Pérez-Pampin, Eva; Navarro-Sarabia, Federico; Moreira, Virginia; Rodríguez de la Serna, Arturo; Magallanes, Berta; Vasilopoulos, Yiannis; Sarafidou, Theologia; Fernández.Nebro, Antonio; Ordóñez, María del Carmen; Narváez, Javier; Cañete, Juan D.; Márquez, Ana; Pascual-Salcedo, Dora; Joven, Beatriz; Carreira, Patricia; Moreno-Ramos, Manuel J.; Cáliz, Rafael; Ferrer, Miguel Ángel; García-Portales, Rosa; Blanco García, Francisco J; Magro, César; Raya, Enrique; Valor, Lara; Alegre-Sancho, Juan J.; Balsa, Alejandro; Martín, Javier; Plant, Darren; Isaacs, John; Morgan, Ann W.; Barton, Anne; Wilson, Anthony G. (BioMed Central, 2015-03-18)
      [Abstract] INTRODUCTION: We have hypothesized that incompatibility between the G1m genotype of the patient and the G1m1 and G1m17 allotypes carried by infliximab (INX) and adalimumab (ADM) could decrease the efficacy of ...