• AGT haplotype in ITGA4 gene is related to antibody-mediated rejection in heart transplant patients 

      Núñez, Lucía; Marrón Liñares, Grecia Manuela; Crespo-Leiro, María Generosa; Barge-Caballero, Eduardo; Álvarez López, Eloy; Suárez-Fuentetaja, Natalia; Paniagua-Martín, María J.; Pombo-Otero, Jorge; Muñiz, Javier; Tan, Carmela D.; Rene Rodríguez, E.; Vázquez Rodríguez, José Manuel (Stanislaw Stepkowski,, 2019-07-23)
      [Abstract] Introduction. One of the main problems involved in heart transplantation (HT) is antibody-mediated rejection (AMR). Many aspects of AMR are still unresolved, including its etiology, diagnosis and treatment. ...
    • Body surface area as a prognostic marker in chronic heart failure patients: results from the Heart Failure Registry of the Heart Failure Association of the European Society of Cardiology 

      Zafrir, Barak; Salman, Nabeeh; Crespo-Leiro, María Generosa; Anker, Stefan; Coats, Andrew J.; Ferrari, Roberto; Filippatos, Gerasimos; Maggioni, Aldo P.; Mebazaa, Alexandre; Piepoli, Massimo Francesco; Ruschitzka, Frank; Paniagua-Martín, María J.; Segovia-Cubero, Javier; Laroche, Cecile; Amir, Offer (Wiley, 2016-07-18)
      [Abstract] AIMS: The 'obesity paradox' is consistently observed in patients with heart failure (HF). We investigated the relationship of body surface area (BSA) to mortality and hospitalizations in patients with chronic ...
    • Cancer in patients with heart failure: incidence, risk factors and prognostic impact 

      Sagastagoitia-Fornie, Marta; Barge-Caballero, Eduardo; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Enríquez-Vázquez, Daniel; Blanco-Canosa, Paula; Grille-Cancela, Zulaika; Jiménez-Navarro, Manuel; Muñiz, Javier; Vázquez-Rodríguez, José M.; Crespo-Leiro, María Generosa (Elsevier, 2022-09-16)
      [Abstract] Aims: To assess the incidence of cancer diagnosis and cancer-related mortality in patients with heart failure (HF). Methods: Observational study based in a prospective cohort of patients with HF referred to ...
    • Circulating Galectin-3 Following Heart Transplant: Long-term Dynamics and Prognostic Value 

      Suárez-Fuentetaja, Natalia; Barge-Caballero, Eduardo; Bayés-Genís, Antoni; Doménech, Nieves; Moreda-Santamaría, Lucía; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Solla-Buceta, Miguel; Estévez-Cid, Francisco; Cuenca-Castillo, José J.; Pombo-Otero, Jorge; Grille-Cancela, Zulaika; Blanco-Canosa, Paula; Muñiz, Javier; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2018-11-23)
      [Abstract] Introduction and objectives: Circulating galectin-3 (Gal-3) is elevated and significantly correlates with all-cause and cardiovascular mortality in patients with heart failure. However, the relationship between ...
    • Circulating miR-181a-5p as a New Biomarker for Acute Cellular Rejection in Heart Transplantation 

      Constanso-Conde, Ignacio; Hermida-Prieto, Manuel; Barge-Caballero, Eduardo; Núñez, Lucía; Pombo-Otero, Jorge; Suárez-Fuentetaja, Natalia; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Pan Lizcano, Ricardo Francisco; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2020-06-07)
      [Abstract] Background: Acute cellular rejection (ACR) is a major complication in heart transplantation (HTx). Endomyocardial biopsy is the reference method for early detection of ACR, but a new non-invasive approach is ...
    • Clinical Characteristics and Long-term outcomes of patients undergoing combined heart-kidney transplantation: a single-center experience 

      López-Sainz, A.; Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Sánchez-Fernández, G.; Fernández Arias, L.; García-Vieites, M.; Alonso-Hernández, Á.; Rodríguez-Rivera-García, J.J.; Crespo-Leiro, María Generosa (Elsevier, 2015-01-30)
      [Abstract] Background. The purpose of the study was to describe clinical characteristics and long-term survival of patients undergoing combined heart-kidney transplant in a single center. Methods. We conducted a retrospective ...
    • Clinical evaluation of rosuvastatin in heart transplant patients with hypercholesterolemia and therapeutic failure of other statin regimens: short-term and long-term efficacy and safety results 

      Barge-Caballero, Gonzalo; Barge-Caballero, Eduardo; Marzoa Rivas, Raquel; Paniagua-Martín, María J.; Barrio-Rodríguez, Alfredo; Naya, Carmen; Blanco-Canosa, Paula; Grille Cancela, Zulaika; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Wiley, 2015-04-23)
      [Abstract] We conducted an observational study of 30 heart transplant recipients with serum low-density lipoprotein cholesterol (LDL-c) >100 mg/dl despite previous statin therapy, who were treated with rosuvastatin 10 mg ...
    • Determinants of Maximal Oxygen Uptake in Patients With Heart Failure 

      Roibal-Pravio, J.; Barge-Caballero, Eduardo; Barbeito Caamaño, Cayetana; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Pardo-Martínez, Patricia; Grille Cancela, Zulaika; Blanco-Canosa, Paula; García-Pinilla, José Manuel; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Wiley Online Library, 2021-03-27)
      [Abstract] Aims Maximum oxygen uptake (VO₂max) is an essential parameter to assess functional capacity of patients with heart failure (HF). We aimed to identify clinical factors that determine its value, as they have not ...
    • Epidemiological study of tricuspid regurgitation after cardiac transplantation: does it influence survival? 

      López-Vilella, Raquel; Paniagua-Martín, María J.; González-Vílchez, Francisco; Donoso Trenado, Víctor; Barge-Caballero, Eduardo; Sánchez-Lázaro, Ignacio; Aller Fernández, Ana Vanesa; Martínez-Dolz, Luis; Crespo-Leiro, María Generosa; Almenar-Bonet, Luis (Frontiers, 2022-03-21)
      [Abstract] Background: Tricuspid valve disease is the most frequent valvulopathy after heart transplantation (HTx). Evidence for the negative effect of post-transplant tricuspid regurgitation (TR) on survival is contradictory. ...
    • Estado serológico frente a Toxoplasma gondii en receptores de trasplante cardiaco: ¿un factor pronóstico independiente? 

      Barge-Caballero, Eduardo; Berbeito-Caamaño, Cayetana; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Solla-Buceta, Miguel; Estévez-Cid, Francisco; Herrera-Noreña, José M.; Cuenca-Castillo, José J.; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2016-08-31)
      [Resumen] Introducción y objetivos. Analizar la influencia pronóstica del estado serológico frente a Toxoplasma gondii en receptores de trasplante cardiaco (TC). Métodos. Se realizó un estudio retrospectivo unicéntrico ...
    • Evaluation of humoral immunity profiles to identify heart recipients at risk for development of severe infections: a multicenter prospective study 

      Sarmiento, Elizabeth; Jaramillo, María; Calahorra, Leticia; Fernández-Yáñez, Juan; Gómez-Sánchez, Miguel; Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Almenar-Bonet, Luis; Cebrián, Mónica; Rábago, Gregorio; Levy, Beltrán; Segovia-Cubero, Javier; Gómez-Bueno, Manuel; López, Javier; Mirabet, Sonia; Navarro, Joaquín; Rodríguez-Molina, Juan José; Fernández-Cruz, Eduardo; Carbone, Javier (Elsevier, 2017)
      [Abstract] BACKGROUND: New biomarkers are necessary to improve detection of the risk of infection in heart transplantation. We performed a multicenter study to evaluate humoral immunity profiles that could better enable ...
    • In-Hospital Post-Operative Infection after Heart Transplantation: Epidemiology, Clinical Management, and Outcome 

      Gómez-López, Rocío; Barge-Caballero, Eduardo; Fernández-Ugidos, Paula; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Solla-Buceta, Miguel; Velasco-García de Sierra, Carlos; Aller-Fernández, Vanesa; Fernández-Arias, Laura; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Mary Ann Liebert, 2020-02-13)
      [Abstract] Background: Infection is a major cause of morbidity and mortality after heart transplantation (HT). Little information about its importance in the immediate post-operative period is available. The aim of this ...
    • In-hospital postoperative infection after heart transplantation: risk factors and development of a novel predictive score 

      Fernández-Ugidos, Paula; Barge-Caballero, Eduardo; Gómez-López, Rocío; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Solla-Buceta, Miguel; Iglesias-Gil, Carmen; Aller-Fernández, Vanesa; González-Barbeito, Miguel; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Wiley, 2019-05-11)
      [Abstract] Introduction: Infection is one of the most significant complications following heart transplantation (HT). The aim of this study was to identify specific risk factors for early postoperative infections in HT ...
    • Incidence, Risk Factors and Prognostic Impact of Cytomegalovirus Infection After Heart Transplantation 

      Méndez-Eirín, Elizabet; Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Grille Cancela, Zulaika; Blanco-Canosa, Paula; Cañizares-Castellanos, Angelina; González Barbeito, Miguel; Aller Fernández, Ana Vanesa; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2020-03-20)
      [Abstract] Introduction and objectives. To assess the risk factors of CMV infection after heart transplant (HT) and its influence on long-term prognosis. Methods. We conducted a retrospective single-centre study of ...
    • Is Becker dystrophinopathy a contraindication to heart transplant?: experience in a single institution 

      Ascencio-Lemus, Marisol Guadalupe; Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Crespo-Leiro, María Generosa (Elsevier, 2018-07-17)
    • Light Chain and Transthyretin Cardiac Amyloidosis: Clinical Characteristics, Natural History and Prognostic Factors 

      Barge-Caballero, Gonzalo; Vázquez-García, Raquel; Barge-Caballero, Eduardo; Couto-Mallón, David; Paniagua-Martín, María J.; Barriales-Villa, Roberto; Piñón-Esteban, Pablo; Bouzas-Mosquera, Alberto; Pombo-Otero, Jorge; Debén-Ariznavarreta, Guillermo; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2021-03-13)
      [Abstract] Introduction and objectives. Light-chain amyloidosis (AL-CA) and transthyretin amyloidosis (ATTR-CA) are the most common types of cardiac amyloidosis (CA). We sought to study the clinical characteristics and ...
    • Mitochondrial DNA haplogroup H as a risk factor for idiopathic dilated cardiomyopathy in Spanish population 

      Fernández Caggiano, Mariana; Barallobre-Barreiro, Javier; Rego-Pérez, Ignacio; Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Grille Cancela, Zulaika; Blanco García, Francisco J; Doménech, Nieves (Elsevier, 2013-03-23)
      [Abstract] Idiopathic dilated cardiomyopathy (IDC) is a structural heart disease with strong genetic background. The different single nucleotide polymorphisms (SNPs) that constitute mitochondrial haplogroups could play an ...
    • Paroxysmal bradyarrhythmias are frequent among heart transplant recipients with unexplained syncope: a study based on implantable loop recorders 

      Martínez-Paz, E.; Barge-Caballero, Eduardo; Álvarez-Roy, Laura; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Mosquera-Pérez, Ignacio; Pérez-Álvarez, Luisa; Muñiz, Javier; Cuenca-Castillo, José J.; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Wiley, 2017-12-13)
    • Polymorphisms in genes related to the complement system and antibody-mediated cardiac allograft rejection 

      Marrón Liñares, Grecia Manuela; Núñez, Lucía; Crespo-Leiro, María Generosa; Barge-Caballero, Eduardo; Pombo-Otero, Jorge; Paniagua-Martín, María J.; Suárez-Fuentetaja, Natalia; Cid, Javier; Grille Cancela, Zulaika; Muñiz, Javier; Tan, Carmela D.; Rene Rodríguez, E.; Vázquez Rodríguez, José Manuel; Hermida-Prieto, Manuel (Elsevier, 2017-07-15)
      [Abstract] Background. Heart transplantation (HT) is a life-saving treatment for patients with end-stage heart failure. One of the main problems after HT is the humoral response termed antibody-mediated rejection (AMR). ...
    • Prevalence of tricuspid regurgitation after orthotopic heart transplantation and its evolution in the follow-up period: a long-term study 

      López-Vilella, Raquel; Paniagua-Martín, María J.; González-Vílchez, Francisco; Donoso Trenado, Víctor; Barge-Caballero, Eduardo; Sánchez-Lázaro, Ignacio; Aller Fernández, Ana Vanesa; Martínez-Dolz, Luis; Crespo-Leiro, María Generosa; Almenar-Bonet, Luis (Elsevier, 2022-10-26)
      [Abstract] Background. Tricuspid regurgitation (TR) after heart transplant (HT) can be an important complication depending on its etiology and severity. This study aims to analyze the prevalence of TR, the causes, and its ...