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Effect of hydrogen sulfide sources on inflammation and catabolic markers on interleukin 1β-stimulated human articular chondrocytes
(Elsevier, 2014-07)
[Abstract] Objective. Hydrogen sulfide (H2S), the third gasotransmitter together with NO and CO, is emerging as a regulator of inflammation. To test if it might offer therapeutic value in the treatment of osteoarthritis ...
Myofascial release therapy in the treatment of occupational mechanical neck pain: a randomized parallel group study
(Wolters Kluwer, 2016-07)
[Abstract] Objective: As myofascial release therapy is currently under development, the objective of this study was to compare the effectiveness of myofascial release therapy with manual therapy for treating occupational ...
Epidemiology of traumatic spinal cord injury in Galicia, Spain: trends over a 20-year period
(Nature, 2017-02-14)
[Abstract] Study design: Observational study with prospective and retrospective monitoring.
Objective: To describe the epidemiological and demographic characteristics of traumatic spinal cord injury (TSCI), and to analyze ...
Therapeutic characteristics of Galician mineral and thermal waters (NW-Spain) ascribed to their local/regional geological setting
(Springer, 2019-03)
[Abstract]
Galicia is located in the NW corner of the Iberian Peninsula (Spain). From a geological point of view, the
territory belongs to the Hercynian chain and, more specifically, to a large outcrop dominated by igneous ...
The nuclear factor-erythroid 2-related factor/heme oxygenase-1 axis is critical for the inflammatory features of type 2 diabetes–associated osteoarthritis
(American Society for Biochemistry and Molecular Biology, 2017-09-01)
[Asbtract] Epidemiological findings support the hypothesis that type 2 diabetes mellitus (T2DM) is a risk factor for osteoarthritis (OA). Moreover, OA cartilage from patients with T2DM exhibits a greater response to ...
Effect of balneotherapy in sulfurous water on an in vivo murine model of osteoarthritis
(Springer, 2019-11-01)
[Abstract] Osteoarthritis (OA) is a chronic joint disease that results in progressive cartilage destruction and subsequently joint dysfunction. Growing evidence indicates beneficial impact of balneological interventions ...
Hydrogen sulfide and inflammatory joint diseases
(Bentham, 2017)
[Abstract] Background: Rheumatoid arthritis (RA) and osteoarthritis (OA) are widespread rheumatic diseases characterized by persistent inflammation and joint destruction. Hydrogen sulfide (H2S) is an endogenous gas with ...
Risks factors of mechanical ventilation in acute traumatic cervical spinal cord injured patients
(Nature, 2017-10-23)
[Abstract] Study design. Descriptive retrospective study.
Objectives. To analyze risk factors associated with mechanical ventilation (MV) in cases of acute traumatic Cervical Spinal Cord Injury (tCSCI).
Setting. Unidad ...
The mitochondrial inhibitor oligomycin induces an inflammatory response in the rat knee joint
(BioMed Central, 2017-06-06)
[Abstract]
Background. Recent findings support a connection between mitochondrial dysfunction and activation of inflammatory pathways in articular cells. This study investigates in vivo in an acute model whether ...
15-Deoxy-Δ-12, 14-prostaglandin J2 acts cooperatively with prednisolone to reduce TGF-β-induced pro-fibrotic pathways in human osteoarthritis fibroblasts
(Elsevier, 2019-03-29)
[Abstract] Abstract
Background/aims: Synovial fibrosis is a pathological process that is observed in several musculoskeletal disorders and characterized by the excessive deposition of extracellular matrix, as well as cell ...