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In search of novel targets for heart disease: myocardin and myocardin-related transcriptional cofactors
(Hindawi, 2012)[Abstract] Growing evidence suggests that gene-regulatory networks, which are responsible for directing cardiovascular development, are altered under stress conditions in the adult heart. The cardiac gene regulatory network ... -
In Search of Transformative Learning for Sustainable Development: Bibliometric Analysis of Recent Scientific Production
(2022)[Abstract] Transformative learning is a key element when it comes to making progress toward sustainable development. This goal requires an education that fosters the empowerment of people and the transformation of institutions, ... -
In silico Analyses of Immune System Protein Interactome Network, Single-Cell RNA Sequencing of Human Tissues, and Artificial Neural Networks Reveal Potential Therapeutic Targets for Drug Repurposing Against COVID-19
(Frontiers Research Foundation, 2021-02-26)[Abstract] Background: There is pressing urgency to identify therapeutic targets and drugs that allow treating COVID-19 patients effectively. Methods: We performed in silico analyses of immune system protein interactome ... -
In situ diffusion experiments: Effect of water sampling on tracer concentrations and parameters
(Elsevier, 2010)[Abstract:] In situ diffusion experiments are performed at underground research laboratories (URL) in clay formations to overcome the limitations of laboratory diffusion experiments and investigate scale effects. Tracers ... -
In Situ Synthesis of Artificial Lipids
(Elsevier, 2022-09-15)[Abstract] Lipids constitute one of the most enigmatic family of biological molecules. Although the importance of lipids as basic units of compartmental structure and energy storage is well-acknowledged, deciphering the ... -
In Vitro and In Vivo Assessment of the Efficacy of Bromoageliferin, an Alkaloid Isolated from the Sponge Agelas dilatata, against Pseudomonas aeruginosa
(MDPI, 2020-06-23)[Abstract] The pyrrole-imidazoles, a group of alkaloids commonly found in marine sponges belonging to the genus Agelas, display a wide range of biological activities. Herein, we report the first chemical study of the ... -
In Vitro Bioaccessibility and Bioavailability of Pollutants in Atmospheric Particulate Matter by Using Simulated Biological Fluids
(2021)[Abstract] In the present Doctoral Thesis, the study of inhalation bioaccessibility and oral bioavailability of pollutants associated to particulate matter (PM) by using in vitro physiologically based extraction test ... -
In vitro comprehensive analysis of VA692 a new chemical entity for the treatment of osteoarthritis
(Elsevier, 2018-08-25)[Abstract] Selective cyclooxigenase (COX)-2 inhibitors were developed to prevent traditional non-steroidal anti-inflammatory drugs (tNSAIDs) gastro-intestinal adverse effects. VA692, a recently disclosed selective COX-2 ... -
In vitro study of the therapeutic potential of brown crude fucoidans in osteoarthritis treatment
(MDPI, 2022-11-17)[Abstract] Osteoarthritis, one of the most common joint degenerative pathologies, still has no cure, and current treatments, such as nonsteroidal anti-inflammatory drugs, can cause serious adverse effects when taken for a ... -
In vivo forced expression of myocardin in ventricular myocardium transiently impairs systolic performance in early neonatal pig heart
(UPV/EHU Press, 2008-01-30)[Abstract] The aim of this study was to determine the effects of forced expression of myocd-A in the left ventricular (LV) myocardium on cardiac performance in early neonatal piglets. LV transfection with the gene for ... -
La (in)estabilidad de la demanda de dinero en Colombia, 2003-2020
(2022)[Resumen] : En este trabajo realizamos un análisis empírico de la evolución del agregado monetario M3 y de sus componentes en Colombia, con el propósito de evaluar las propiedades de estabilidad de cada uno de los activos ... -
La (in)movilidad a debate: diez años de estudio de las migraciones en la España entre crisis (2009-2021)
(Instituto Universitario de Estudios sobre Migraciones. Universidad Pontificia Comillas, 2022)[Resumen] En las últimas décadas, el campo de los estudios migratorios, tanto en España como a nivel internacional, había constatado el poder de la movilidad como agente de estratificación social en el contexto global. ... -
(In)seguridad y "caminabilidad" en el Ayuntamiento de Narón: perspectiva de género y diseño urbano
(2022)[Resumen] El presente trabajo de investigación pretende realizar un análisis con perspectiva de género sobre la percepción de la (in)seguridad en la “caminabilidad” percibida por la población del municipio de Narón, en la ... -
In-contest body acceleration profiles for the judo male and female weight divisions
(Frontiers, 2024-03-11)[Abstract] Introduction: This study aimed to determine the body accelerations (BA) profile of the judo contest of the male and female weight divisions and to ascertain the involvement of the vertical, mediolateral and ... -
In-Depth Analysis of the Role of the Acinetobactin Cluster in the Virulence of Acinetobacter baumannii
(Frontiers, 2021-10-05)[Abstract] Acinetobacter baumannii is a multidrug-resistant pathogen that represents a serious threat to global health. A. baumannii possesses a wide range of virulence factors that contribute to the bacterial pathogenicity. ... -
In-depth study of a novel class of ditopic gadolinium(III)-based MRI probes sensitive to zwitterionic neurotransmitters
(Frontiers, 2019-07-24)[Abstract] The efficacy of Gd-based low-molecular weight ditopic MRI probes on binding zwitterionic neurotransmitters (ZNTs) relies on their structural compatibility. ZNTs are challenging biomarkers for monitoring chemical ... -
In-hospital heart rate reduction and its relation to outcomes of heart failure patients with sinus rhythm: results from the polish part of the European Society of Cardiology Heart Failure pilot and long-term registries
(Via Medica, 2018-08-29)[Abstract] Background: Currently, there is no information on whether in-hospital heart rate (HR) reduction has an influence on risk of death or rehospitalization. The study evaluates the relation between inhospital HR ... -
In-hospital mortality due to acute myocardial infarction: relevance of type of hospital and care provided: RECALCAR study
(Elsevier, 2013-09-14)[Abstract] Introduction and objectives. To investigate the relationship between in-hospital mortality due to acute myocardial infarction and type of hospital, discharge service, and treatment provided. Methods. Retrospective ... -
In-Hospital Post-Operative Infection after Heart Transplantation: Epidemiology, Clinical Management, and Outcome
(Mary Ann Liebert, 2020-02-13)[Abstract] Background: Infection is a major cause of morbidity and mortality after heart transplantation (HT). Little information about its importance in the immediate post-operative period is available. The aim of this ...