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Next-generation sequencing and quantitative proteomics of Hutchinson-Gilford progeria syndrome-derived cells point to a role of nucleotide metabolism in premature aging
(PLOS, 2018-10-31)
[Abstract] Hutchinson-Gilford progeria syndrome (HGPS) is a very rare fatal disease characterized for accelerated aging. Although the causal agent, a point mutation in LMNA gene, was identified more than a decade ago, the ...
Exploring genetic outcomes as frailty biomakers
(Oxford, 2018-04-19)
[Abstract] Frailty has emerged as a reliable measure of the aging process. Because the early detection of frailty is crucial to prevent or even revert it, the use of biomarkers would allow an earlier and more objective ...
Changes in frailty status in a community-dwelling cohort of older adults: the VERISAÚDE study
(Elsevier, 2018-11-15)
[Abstract] Objectives: Greater understanding of changes in the degree of frailty is important for clarifying the natural history of frailty and may help clinical decision-making regarding preventive interventions. The ...
Interrelation of individual, country and activity constraints in motor activities of daily living among typically developing children: a cross-sectional comparison of spanish and dutch populations
(MDPI, 2020-03-05)
[Abstract]
Motor performance is influenced by individual, environmental, and task constraints.
Children perform differently according to individual (i.e., sex), environmental (i.e., country), and task
(i.e., type of ...
Cognitive frailty: a conceptual systematic review and an operational proposal for future research
(Elsevier, 2018-12-07)
[Abstract] Objective. To analyze the definition of “cognitive frailty” and to study the conceptual and operational definitions used and their implications for empirical research. The relationships between this concept and ...
Identifying children with developmental coordination disorder via parental questionnaires. Spanish reference norms for the DCDDaily-Q-ES and correlation with the DCDQ-ES
(MDPI, 2020-01-15)
[Abstract]
Developmental Coordination Disorder (DCD) is one of the most prevalent
neurodevelopmental disorders in school-aged children, with major consequences in psychosocial
and physical health. Adequate identification ...
Prevalencia de osteoporosis, estimación de la probabilidad de fractura y estudio del metabolismo óseo en pacientes con reciente diagnóstico de cáncer de próstata en el área sanitaria de Lugo
(Elsevier, 2017-06-17)
[Resumen] Objetivo.
Estudiar la prevalencia de osteoporosis y probabilidad de fractura en pacientes diagnosticados de cáncer de próstata.
Diseño.
Estudio observacional, descriptivo y transversal.
Emplazamiento. ...
Simultaneous utilization of fine and coarse recycled concrete aggregate for the fabrication and experimental analysis of the structural performance of precast reinforced and prestressed concrete elements
(2016)
[Abstract] This doctoral thesis aims at taking a step forward in concrete recycling, since it is proposed
to replace simultaneously the fine and coarse fraction of the aggregate without having to
previously sieve the raw ...
Effect of fine and coarse recycled concrete aggregate on the mechanical behavior of precast reinforced beams: Comparison of FE simulations, theoretical, and experimental results on real scale beams
(Elsevier, 2018)
[Abstract:] In this work, we present the effect of using coarse and fine recycled aggregate jointly as a partial replacement of natural aggregate in self-compacting concrete in the mechanical performance of precast beams. ...