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Incidence and prognosis of colorectal cancer after heart transplantation: data from the spanish post-heart transplant tumor registry
dc.contributor.author | Sagastagoitia-Fornie, Marta | |
dc.contributor.author | Morán-Fernández, Laura | |
dc.contributor.author | Blázquez-Bermejo, Zorba | |
dc.contributor.author | Díaz-Molina, Beatriz | |
dc.contributor.author | Gómez-Bueno, Manuel | |
dc.contributor.author | Almenar-Bonet, Luis | |
dc.contributor.author | López Granados, Amador | |
dc.contributor.author | González-Vílchez, Francisco | |
dc.contributor.author | Mirabet-Pérez, Sonia | |
dc.contributor.author | García-Romero, Elena | |
dc.contributor.author | Sobrino-Márquez, José Manuel | |
dc.contributor.author | Rábago Juan-Aracil, Gregorio | |
dc.contributor.author | Castel-Lavilla, María Ángeles | |
dc.contributor.author | Blasco-Peiró, Teresa | |
dc.contributor.author | Garrido-Bravo, Iris P. | |
dc.contributor.author | De la Fuente-Galán, Luis | |
dc.contributor.author | Muñiz, Javier | |
dc.contributor.author | Crespo-Leiro, María Generosa | |
dc.date.accessioned | 2023-10-20T09:07:58Z | |
dc.date.available | 2023-10-20T09:07:58Z | |
dc.date.issued | 2023-05 | |
dc.identifier.citation | Sagastagoitia-Fornie M, Morán-Fernández L, Blázquez-Bermejo Z, Díaz-Molina B, Gómez-Bueno M, Almenar-Bonet L, López-Granados A, González-Vílchez F, Mirabet-Pérez S, García-Romero E, Sobrino-Márquez JM, Rábago Juan-Aracil G, Castel-Lavilla MA, Blasco-Peiro T, Garrido-Bravo I, De La Fuente-Galán L, Muñiz J, Crespo-Leiro MG. Incidence and prognosis of colorectal cancer after heart transplantation: data from the spanish post-heart transplant tumor registry. Transpl Int. 2023 May 19;36:11042. | es_ES |
dc.identifier.issn | 0934-0874 | |
dc.identifier.uri | http://hdl.handle.net/2183/33854 | |
dc.description | Observational study | es_ES |
dc.description.abstract | [Abstract] In this observational and multicenter study, that included all patients who underwent a heart transplantation (HT) in Spain from 1984 to 2018, we analyzed the incidence, management, and prognosis of colorectal cancer (CRC) after HT. Of 6,244 patients with a HT and a median follow-up of 8.8 years since the procedure, 116 CRC cases (11.5% of noncutaneous solid cancers other than lymphoma registered) were diagnosed, mainly adenocarcinomas, after a mean of 9.3 years post-HT. The incidence of CRC increased with age at HT from 56.6 per 100,000 person-years among under 45 year olds to 436.4 per 100,000 person-years among over 64 year olds. The incidence rates for age-at-diagnosis groups were significantly greater than those estimated for the general Spanish population. Curative surgery, performed for 62 of 74 operable tumors, increased the probability of patient survival since a diagnosis of CRC, from 31.6% to 75.7% at 2 years, and from 15.8% to 48.6% at 5 years, compared to patients with inoperable tumors. Our results suggest that the incidence of CRC among HT patients is greater than in the general population, increasing with age at HT. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Frontiers | es_ES |
dc.relation.uri | https://doi.org/10.3389/ti.2023.11042 | es_ES |
dc.rights | Creative Commons Attribution 4.0 International License (CC-BY 4.0) | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Colorectal cancer | es_ES |
dc.subject | Heart transplantation | es_ES |
dc.subject | Incidence | es_ES |
dc.subject | Managment | es_ES |
dc.subject | Prognosis | es_ES |
dc.title | Incidence and prognosis of colorectal cancer after heart transplantation: data from the spanish post-heart transplant tumor registry | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.access | info:eu-repo/semantics/openAccess | es_ES |
UDC.journalTitle | Transplant International | es_ES |
UDC.volume | 36 | es_ES |
UDC.startPage | 11042 | es_ES |
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