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Temporal trends in the use and outcomes of temporary mechanical circulatory support as a bridge to cardiac transplantation in Spain. Final report of the ASIS-TC study
dc.contributor.author | Barge-Caballero, Eduardo | |
dc.contributor.author | González-Vílchez, Francisco | |
dc.contributor.author | Almenar-Bonet, Luis | |
dc.contributor.author | García-Cosío, María Dolores | |
dc.contributor.author | González-Costello, José | |
dc.contributor.author | Gómez-Bueno, Manuel | |
dc.contributor.author | Castel-Lavilla, María Ángeles | |
dc.contributor.author | Lambert-Rodríguez, José Luis | |
dc.contributor.author | Martínez-Sellés, Manuel | |
dc.contributor.author | Mirabet-Pérez, Sonia | |
dc.contributor.author | De la Fuente-Galán, Luis | |
dc.contributor.author | Hervás-Sotomayor, Daniela | |
dc.contributor.author | Rangel-Sousa, Diego | |
dc.contributor.author | Garrido-Bravo, Iris P. | |
dc.contributor.author | Blasco-Peiró, Teresa | |
dc.contributor.author | Rábago Juan-Aracil, Gregorio | |
dc.contributor.author | Muñiz, Javier | |
dc.contributor.author | Crespo-Leiro, María Generosa | |
dc.date.accessioned | 2023-03-17T11:33:10Z | |
dc.date.issued | 2022-11-09 | |
dc.identifier.citation | Barge-Caballero E, González-Vílchez F, Almenar-Bonet L, Carmena MDG, González-Costello J, Gómez-Bueno M, Castel-Lavilla MÁ, Lambert-Rodríguez JL, Martínez-Sellés M, Mirabet-Pérez S, la Fuente-Galán L, Hervás-Sotomayor D, Rangel-Sousa D, Garrido-Bravo IP, Blasco-Peiró T, Juan-Aracil GR, Muñiz J, Crespo-Leiro MG. Temporal trends in the use and outcomes of temporary mechanical circulatory support as a bridge to cardiac transplantation in Spain. Final report of the ASIS-TC study. J Heart Lung Transplant. 2023 Abr;42(4):488-502. | es_ES |
dc.identifier.issn | 1053-2498 | |
dc.identifier.uri | http://hdl.handle.net/2183/32712 | |
dc.description.abstract | [Abstract] Background: We aimed to describe recent trends in the use and outcomes of temporary mechanical circulatory support (MCS) as a bridge to heart transplantation (HTx) in Spain. Methods: Retrospective case-by-case analysis of 1,036 patients listed for emergency HTx while on temporary MCS in 16 Spanish institutions from January 1st, 2010 to December 31st, 2020. Patients were classified in 3 eras according to changes in donor allocation criteria (Era 1: January 2010/May 2014; Era 2: June 2014/May 2017; Era 3: June 2017/December 2020). Results: Over time, the proportion of candidates listed with intra-aortic balloon pumps decreased (Era 1 = 55.9%, Era 2 = 32%, Era 3 = 0.9%; p < 0.001), while the proportion of candidates listed with surgical continuous-flow temporary VADs (Era 1 = 10.6%, Era 2 = 32%, Era 3 = 49.1%; p < 0.001) and percutaneous VADs (Era 1 = 0.3%, Era 2 = 6.3%; Era 3 = 17.2%; p < 0.001) increased. Rates of HTx increased from Era 1 (79.4%) to Era 2 (87.8%), and Era 3 (87%) (p = 0.004), while rates of death before HTx decreased (Era 1 = 17.7%; Era 2 = 11%, Era 3 = 12.4%; p = 0.037) Median time from listing to HTx increased in patients supported with intra-aortic balloon pumps (Era 1 = 8 days, Era 2 = 15 days; p < 0.001) but remained stable in other candidates (Era 1 = 6 days; Era 2 = 5 days; Era 3 = 6 days; p = 0.134). One-year post-transplant survival was 71.4% in Era 1, 79.3% in Era 2, and 76.5% in Era 3 (p = 0.112). Preoperative bridging with ECMO was associated with increased 1-year post-transplant mortality (adjusted HR=1.71; 95% CI 1.15-2.53; p = 0.008). Conclusions: During the period 2010 to 2020, successive changes in the Spanish organ allocation protocol were followed by a significant increase of the rate of HTx and a significant reduction of waiting list mortality in candidates supported with temporary MCS. One-year post-transplant survival rates remained acceptable. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.relation.uri | https://doi.org/10.1016/j.healun.2022.10.020 | es_ES |
dc.subject | ECMO | es_ES |
dc.subject | Heart transplantation | es_ES |
dc.subject | Mechanical circulatory support | es_ES |
dc.subject | Ventricular assist devices | es_ES |
dc.title | Temporal trends in the use and outcomes of temporary mechanical circulatory support as a bridge to cardiac transplantation in Spain. Final report of the ASIS-TC study | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.access | info:eu-repo/semantics/embargoedAccess | es_ES |
dc.date.embargoEndDate | 2023-11-09 | es_ES |
dc.date.embargoLift | 2023-11-09 | |
UDC.journalTitle | The Journal of Heart and Lung Transplantation | es_ES |
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