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dc.contributor.authorOrtiz-Bautista, Carlos
dc.contributor.authorMuñiz, Javier
dc.contributor.authorAlmenar-Bonet, Luis
dc.contributor.authorCrespo-Leiro, María Generosa
dc.contributor.authorSobrino-Márquez, José Manuel
dc.contributor.authorFarrero-Torres, Marta
dc.contributor.authorGarcía-Cosío, M. Dolores
dc.contributor.authorDíaz-Molina, Beatriz
dc.contributor.authorZegrí-Reiriz, Isabel
dc.contributor.authorGonzález-Vílchez, Francisco
dc.contributor.authorBlázquez-Bermejo, Zorba
dc.contributor.authorLópez Granados, Amador
dc.contributor.authorGómez-Bueno, Manuel
dc.contributor.authorDe la Fuente-Galán, Luis
dc.contributor.authorBlasco-Peiró, Teresa
dc.contributor.authorGarrido-Bravo, Iris P.
dc.contributor.authorGarcía-Romero, Elena
dc.contributor.authorRábago Juan-Aracil, Gregorio
dc.contributor.authorGarcía-Guereta, Luis
dc.contributor.authorDelgado-Jiménez, Juan F.
dc.date.accessioned2022-09-09T08:30:35Z
dc.date.issued2022-07-13
dc.identifier.citationOrtiz-Bautista C, Muñiz J, Almenar-Bonet L, Crespo-Leiro MG, Sobrino-Márquez JM, Farrero-Torres M, García-Cosio MD, Díaz-Molina B, Zegrí-Reiriz I, González-Vilchez F, Blázquez-Bermejo Z, López Granados A, Gómez-Bueno M, de la Fuente-Galán L, Blasco-Peiró T, Garrido-Bravo IP, García-Romero E, Rábago Juan-Aracil G, García-Guereta L, Delgado-Jiménez JF. Utility of the IMPACT score for predicting heart transplant mortality. Analysis on a contemporary cohort of the Spanish Heart Transplant Registry. Clin Transplant. 2022 Sep;36(9):e14774.es_ES
dc.identifier.issn0902-0063
dc.identifier.urihttp://hdl.handle.net/2183/31540
dc.description.abstract[Abstract] Introduction and objectives: The Index for Mortality Prediction After Cardiac Transplantation (IMPACT) score was derived and validated as a predictor of mortality after heart transplantation (HT). The primary objective of this work is to externally validate the IMPACT score in a contemporary Spanish cohort. Methods: Spanish Heart Transplant Registry data were used to identify adult (>16 years) HT patients between January 2000 and December 2015. Retransplantation, multiorgan transplantation and patients in whom at least one of the variables required to calculate the IMPACT score was missing were excluded from the analysis (N = 2810). Results: Median value of the IMPACT score was five points (IQR: 3, 8). Overall, 1-year survival rate was 79.1%. Kaplan-Meier 1-year survival rates by IMPACT score categories (0-2, 3-5, 6-9, 10-14, ≥15) were 84.4%, 81.5%, 79.3%, 77.3%, and 58.5%, respectively (Log-Rank test: p < .001). Performance analysis showed a good calibration (Hosmer-Lemeshow chi-square for 1 year was 7.56; p = .47) and poor discrimination ability (AUC-ROC .59) of the IMPACT score as a predictive model. Conclusions: In a contemporary Spanish cohort, the IMPACT score failed to accurately predict the risk of death after HT.es_ES
dc.language.isoenges_ES
dc.publisherWileyes_ES
dc.relation.urihttps://doi.org/10.1111/ctr.14774es_ES
dc.rightsThis is the peer reviewed version of the following article, which has been published in final form at Wiley Online Library. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.es_ES
dc.subjectIMPACT scorees_ES
dc.subjectGraft survivales_ES
dc.subjectHeart transplantationes_ES
dc.subjectOrgan allocationes_ES
dc.subjectPrognostic model researches_ES
dc.titleUtility of the IMPACT score for predicting heart transplant mortality: analysis on a contemporary cohort of the Spanish Heart Transplant Registryes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessinfo:eu-repo/semantics/embargoedAccesses_ES
dc.date.embargoEndDate2023-07-13es_ES
dc.date.embargoLift2023-07-13
UDC.journalTitleClinical Transplantationes_ES


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