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Mostrando ítems 51-60 de 195
La artrosis y la ateroesclerosis de la articulación
(Elsevier, 2018-09-08)
Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies
(Wiley, 2013-12-10)
[Abstract] Objective: To assess candidate genes for association with osteoarthritis (OA) and identify promising genetic factors and, secondarily, to assess the candidate gene approach in OA.
Methods: A total of 199 ...
Mitochondrial DNA in Osteoarthritis Disease
(Springer, 2020-09-25)
[Abstract]
Osteoarthritis (OA) is the most prevalent chronic joint disease, and we actually know that the activation of maladaptive responses to injury, including pro-inflammatory pathways, leads to the loss of normal ...
What did we learn from 'omics' studies in osteoarthritis
(Wolters Kluwer, 2018-01-01)
[Abstract] Purpose of review: 'Omics' technologies developed for the massive analysis of the major biologically relevant molecules (genes, proteins, metabolites) have been applied to the study of osteoarthritis (OA) for ...
Clinical, Patient-Reported, and Ultrasound Outcomes from an Open-Label, 12-week Observational Study of Certolizumab Pegol in Spanish Patients with Rheumatoid Arthritis with or without Prior Anti-TNF Exposure
(Elsevier, 2018-09-17)
[Abstract] Objectives: To assess the effectiveness and safety of certolizumab pegol (CZP) in Spanish patients with RA.
Materials and methods: SONAR (NCT01526434), a 12-week, open-label, prospective, observational, ...
Efficacy, Safety and Cost-Effectiveness of Methotrexate, Adalimumab or Their Combination in Non-infectious Non-anterior Uveitis: A Protocol for a Multicentre, Randomised, Parallel Three Arms, Active-Controlled, Phase III Open Label With Blinded Outcome Assessment Study
(BMJ Publishing Group, 2022-03-22)
[Abstract]
Introduction: Non-infectious uveitis include a heterogeneous group of sight-threatening and incapacitating conditions. Their correct management sometimes requires the use of immunosuppressive drugs (ISDs), ...
Mitochondrial haplogroups define two phenotypes of osteoarthritis
(Frontiers, 2012-05-11)
[Abstract] Objective: To assess a mitochondrion-related phenotype in patients with osteoarthritis (OA).
Methods: Serum levels of the following OA-related biomarkers: matrix metalloproteinase-1 (MMP-1); MMP-3; MMP-13; ...
Ovine mesenchymal stromal cells for osteochondral tissue engineering
(Elsevier, 2017-04)
Umbilical Cord as a Mesenchymal Stem Cell Source for Treating Joint Pathologies
(Baishideng, 2011-06-18)
[Abstract] Articular cartilage disorders and injuries often result in life-long chronic pain and compromised quality of life. Regrettably, the regeneration of articular cartilage is a continuing challenge for biomedical ...
Genetic biomarkers in osteoarthritis: a quick overview
(Faculty Opinions, 2021-11-10)
[Abstract] Osteoarthritis (OA) is a chronic musculoskeletal disease with a polygenic and heterogeneous nature. In addition, when clinical manifestations appear, the evolution of the disease is usually already irreversible. ...