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dc.contributor.authorTargher, Giovanni
dc.contributor.authorDauriz, Marco
dc.contributor.authorLaroche, Cecile
dc.contributor.authorTemporelli, Pier Luigi
dc.contributor.authorHassanein, Mahmoud
dc.contributor.authorSeferovic, Petar M.
dc.contributor.authorDrozdz, Jaroslaw
dc.contributor.authorFerrari, Roberto
dc.contributor.authorAnker, Stefan
dc.contributor.authorCoats, Andrew
dc.contributor.authorFilippatos, Gerasimos
dc.contributor.authorCrespo-Leiro, María Generosa
dc.contributor.authorMebazaa, Alexandre
dc.contributor.authorPiepoli, Massimo F.
dc.contributor.authorMaggioni, Aldo P.
dc.contributor.authorTavazzi, Luigi
dc.date.accessioned2019-03-12T12:40:39Z
dc.date.available2019-03-12T12:40:39Z
dc.date.issued2016-10-28
dc.identifier.citationTargher G, Dauriz M, Laroche C, et al. In‐hospital and 1‐year mortality associated with diabetes in patients with acute heart failure: results from the ESC‐HFA Heart Failure Long‐Term Registry. Eur J Heart Fail. 2017; 19(1): 54-65es_ES
dc.identifier.issn1879-0844
dc.identifier.urihttp://hdl.handle.net/2183/22184
dc.description.abstract[Abstract] AIMS: The aim of this study was to evaluate the in-hospital and 1-year prognostic impact of diabetes and elevated blood glucose levels at hospital admission in patients with acute heart failure (HF). METHODS AND RESULTS: We studied a multinational cohort of 6926 hospitalized patients with acute HF enrolled in the European Society of Cardiology (ESC) and Heart Failure Association (HFA) Long-Term Registry, of whom 49.4% (n = 3422) had known or previously undiagnosed diabetes (defined as self-reported history, or medication use, or fasting glucose levels ≥7.0 mmol/L or haemoglobin A1c ≥6.5%). Compared with those without diabetes, patients with known or previously undiagnosed diabetes had higher cumulative rates of in-hospital mortality, 1-year mortality, and 1-year HF re-hospitalization that occurred independently of multiple clinical risk factors: in-hospital mortality [6.8 vs. 4.4%; adjusted hazard ratio (HR) 1.774; 95% confidence interval (CI) 1.282-2.456, P < 0.001], 1-year all-cause mortality (27.5 vs. 24%; adjusted HR 1.162; 95% CI 1.020-1.325, P = 0.024), and 1-year hospital re-admissions for HF (23.2 vs. 18.5%; adjusted HR 1.320; 95% CI 1.139-1.530, P < 0.001). Moreover, elevated admission blood glucose concentrations were powerfully prognostic for in-hospital mortality, but not for 1-year mortality or re-hospitalizations, in both patients with and without diabetes. CONCLUSIONS: Among patients hospitalized for acute HF, the presence of diabetes is independently associated with an increased risk of in-hospital mortality, 1-year all-cause mortality, and 1-year re-hospitalizations for HF, underscoring the need for more effective and personalized treatments of diabetes in this particularly high-risk patient population.es_ES
dc.language.isoenges_ES
dc.publisherWileyes_ES
dc.relation.urihttps://doi.org/10.1002/ejhf.679es_ES
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 Españaes_ES
dc.rightsThis is the peer reviewed version of the article which has been published in final form at Wiley Online Library. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for self-archiving.es_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.subjectCo-morbiditieses_ES
dc.subjectDiabeteses_ES
dc.subjectAcute heart failurees_ES
dc.subjectObservational outcome studyes_ES
dc.titleIn‐hospital and 1‐year mortality associated with diabetes in patients with acute heart failure: results from the ESC‐HFA Heart Failure Long‐Term Registryes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessinfo:eu-repo/semantics/openAccesses_ES
UDC.journalTitleEuropean Journal of Heart Failurees_ES
UDC.volume19es_ES
UDC.issue1es_ES
UDC.startPage54es_ES
UDC.endPage65es_ES


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