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dc.contributor.authorEspada, Jesús
dc.contributor.authorCalvo, Moisés B.
dc.contributor.authorDíaz-Prado, Silvia
dc.contributor.authorMedina, Vanessa
dc.date.accessioned2017-02-01T10:44:38Z
dc.date.available2017-02-01T10:44:38Z
dc.date.issued2009-07-15
dc.identifier.citationEspada J, Calvo MB, Díaz-Prado S, Medina V. Wnt signalling and cancer stem cells. Clin Trans Oncol. 2009;11(7):411-427es_ES
dc.identifier.issn1699-048X
dc.identifier.issn1699-3055
dc.identifier.urihttp://hdl.handle.net/2183/18037
dc.description.abstract[Abstract] Intracellular signalling mediated by secreted Wnt proteins is essential for the establishment of cell fates and proper tissue patterning during embryo development and for the regulation of tissue homeostasis and stem cell function in adult tissues. Aberrant activation of Wnt signalling pathways has been directly linked to the genesis of different tumours. Here, the components and molecular mechanisms implicated in the transduction of Wnt signal, along with important results supporting a central role for this signalling pathway in stem cell function regulation and carcinogenesis will be briefly reviewed.es_ES
dc.description.sponsorshipMinisterio de Ciencia e Innovación; SAF2008-00609es_ES
dc.language.isoenges_ES
dc.publisherSpringeres_ES
dc.relation.urihttp://dx.doi.org/10.1007/s12094-009-0380-4es_ES
dc.rightsThe final publication is avaliable at Springer Linkes_ES
dc.subjectWntes_ES
dc.subjectBeta-catenines_ES
dc.subjectCanceres_ES
dc.subjectCancer stem cellses_ES
dc.titleWnt signalling and cancer stem cellses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessinfo:eu-repo/semantics/openAccesses_ES
UDC.journalTitleClinical and Translational Oncologyes_ES
UDC.volume11es_ES
UDC.issue7es_ES
UDC.startPage411es_ES
UDC.endPage427es_ES


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