• POT1 and damage response malfunction trigger acquisition of somatic activating mutations in the VEGF pathway in cardiac angiosarcomas 

      Calvete, Oriol; García-Pavía, Pablo; Domínguez, Fernando; Mosteiro, Lluc; Pérez-Cabornero, Lucía; Cantalapiedra, Diego; Zorio, Esther; Ramón y Cajal, Teresa; Crespo-Leiro, María Generosa; Teulé, Álex; Lázaro, Conxi; Morente, Manuel; Urioste, Miguel; Benitez, Javier (American Heart Association, 2019-09-17)
      [Abstract] Background Mutations in the POT1 gene explain abnormally long telomeres and multiple tumors including cardiac angiosarcomas (CAS). However, the link between long telomeres and tumorigenesis is poorly ...