• Molecular states associated with dysfunction and graft loss in heart transplants 

      Halloran, Philip F.; Madill-Thomsen, Katelynn; Mackova, Martina; Aliabadi-Zuckermann, Arezu Z.; Cadeiras, Martin; Crespo-Leiro, María Generosa; Depasquale, Eugene C.; Deng, Mario; Gökler, Johannes; Hall, Shelley A.; Kim, Daniel H.; Kobashigawa, Jon; Macdonald, Peter; Potena, Luciano; Shah, Keyur; Stehlik, Josef; Zuckermann, Andreas; Reeve, Jeff (Elsevier, 2023-11-30)
      [Abstract] Background: We explored the changes in gene expression correlating with dysfunction and graft failure in endomyocardial biopsies. Methods: Genome-wide microarrays (19,462 genes) were used to define mRNA ...
    • Redefining the molecular rejection states in 3230 heart transplant biopsies: relationships to parenchymal injury and graft survival 

      Halloran, Phillip F.; Madill-Thomsen, Katelynn; Aliabadi-Zuckermann, Arezu Z.; Cadeiras, Martín; Crespo-Leiro, María Generosa; Depasquale, Eugene C.; Deng, Mario; Gökler, Johannes; Hall, Shelley A.; Jamil, Aayla; Kim, Daniel H.; Kobashigawa, Jon; Macdonald, Peter; Melenovsky, Vojtech; Patel, Jignesh; Potena, Luciano; Shah, Keyur; Stehlik, Josef; Zuckermann, Andreas (Elsevier, 2024-03-26)
      [Abstract] The first-generation Molecular Microscope (MMDx) system for heart transplant endomyocardial biopsies used expression of rejection-associated transcripts (RATs) to diagnose not only T cell-mediated rejection ...