Listar INIBIC-ICATC - Artigos por autor "Fernández-Caggiano, Mariana"

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    • Mitochondrial Pyruvate Carrier Abundance Mediates Pathological Cardiac Hypertrophy 

      Fernández-Caggiano, Mariana; Kamynina, Alisa; Francois, Asvi A.; Prysyazhna, Oleksandra; Eykyn, Thomas R.; Krasemann, Susanne; Crespo-Leiro, María Generosa; García-Vieites, M.; Bianchi, Katiuscia; Morales, Valle; Doménech, Nieves; Eaton, Philip (Springer Nature, 2020-10-26)
      [Abstract] Cardiomyocytes rely on metabolic substrates, not only to fuel cardiac output, but also for growth and remodelling during stress. Here we show that mitochondrial pyruvate carrier (MPC) abundance mediates ...

    • Reduced mitochondrial pyruvate carrier expression in hearts with heart failure and reduced ejection fraction patients: ischemic vs. non-ischemic origin 

      López-Vázquez, Paula; Fernández-Caggiano, Mariana; Barge-Caballero, Eduardo; Barge-Caballero, Gonzalo; Couto-Mallón, David; Grille-Cancela, Zulaika; Blanco-Canosa, Paula; Paniagua-Martín, María J.; Enríquez-Vázquez, Daniel; Vázquez-Rodríguez, José M.; Doménech, Nieves; Crespo-Leiro, María Generosa (Frontiers, 2024-03-08)
      [Abstract] Introduction and objectives: Mitochondrial pyruvate carrier (MPC) mediates the entry of pyruvate into mitochondria, determining whether pyruvate is incorporated into the Krebs cycle or metabolized in the cytosol. ...