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Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
(BMJ, 2015-01-14)
[Abstract] Objectives. To compare the efficacy and safety of chondroitin sulfate plus glucosamine hydrochloride (CS+GH) versus celecoxib in patients with knee osteoarthritis and severe pain.
Methods. Double-blind ...
Hyperlipidemic microenvironment conditionates damage mechanisms in human chondrocytes by oxidative stress
(BMC, 2017-06-12)
[Abstract] Background, Currently, two pathogenic pathways describe the role of obesity in osteoarthritis (OA); one through biomechanical stress, and the other by the contribution of systemic inflammation. The aim of this ...
Characterization of chronic HCV infection in Northwest Spain: impact of the treatment strategic plan of the Spanish National Health Service on HCV cure
(Wiley, 2017-03-14)
[Abstract] The aim of the study was to characterize HCV infection in Northwest Spain and assess the impact of the Spanish Strategic Plan to cure HCV infection. Overall, 387 patients were included (60.9% HIV/HCV coinfected ...
2023 Focused Update of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure
(Oxford Academic, 2023-10-01)
Circulating microRNAs: molecular microsensors in gastrointestinal cancer
(MPDI, 2012-07-09)
[Abstract] MicroRNAs (miRNAs) are small molecules of single strand non-coding RNAs, which are able to regulate gene expression. miRNAs have been involved in multiple cellular processes, such as proliferation, apoptosis and ...
New insights into molecular mechanisms of sunitinib-associated side effects
(American Association for Cancer Research, 2011-12)
[Abstract] The introduction of targeted therapy represents a major advance in the treatment of tumor progression. Targeted agents are a novel therapeutic approach developed to disrupt different cellular signaling pathways. ...
Amentadione from the Alga Cystoseira usneoides as a Novel Osteoarthritis Protective Agent in an Ex Vivo Co-Culture OA Model
(MDPI, 2020-12-07)
[Abstract] Osteoarthritis (OA) remains a prevalent chronic disease without effective prevention and treatment. Amentadione (YP), a meroditerpenoid purified from the alga Cystoseira usneoides, has demonstrated anti-inflammatory ...
Cancer incidence in persons living with HIV
(Oxford University Press para Infectious Diseases Society of America, 2016-11-14)
Prognostic significance of heart rate and its long-term trend in cardiac transplant patients
(Elsevier para Sociedad Española de Cardiología, 2015-04-11)
[Abstract] Introduction and objectives. The aim of the present study was to examine the prognostic significance of heart rate and its trend in heart transplantation.
Methods. This observational study enrolled 170 patients ...