ListarInstituto de Investigación Biomédica da Coruña (INIBIC) por tema "Proteomics"

Mostrando ítems 1-4 de 4

    • Discovery of circulating proteins associated to knee radiographic osteoarthritis 

      Lourido Salas, Lucía María; Ayoglu, Burcu; Fernández-Tajes, Juan; Oreiro, Natividad; Henjes, Frauke; Hellström, Cecilia; Schwenk, Jochen M.; Ruiz-Romero, Cristina; Nilsson, Peter; Blanco García, Francisco J (Nature, 2017-03-09)
      [Abstract] Currently there are no sufficiently sensitive biomarkers able to reflect changes in joint remodelling during osteoarthritis (OA). In this work, we took an affinity proteomic approach to profile serum samples for ...

    • Predictive modeling of therapeutic response to chondroitin sulfate/glucosamine hydrochloride in knee osteoarthritis 

      Blanco García, Francisco J; Camacho Encina, María; González-Rodríguez, Lucía; Rego-Pérez, Ignacio; Mateos, Jesús; Fernández-Puente, Patricia; Lourido Salas, Lucía María; Rocha Loureda, Beatriz; Picchi, Florencia; Silva-Díaz, María T.; Herrero, Marta; Martínez, Helena; Verges, Josep; Ruiz-Romero, Cristina; Calamia, Valentina (Sage, 2019-08-24)
      [Abstract] Background: In the present study, we explored potential protein biomarkers useful to predict the therapeutic response of knee osteoarthritis (KOA) patients treated with pharmaceutical grade Chondroitin ...

    • Proteomic profiling of human menisci from mild joint degeneration and end-stage osteoarthritis versus healthy controls 

      Paz-González, Rocío; Turkiewicz, Aleksandra; Ali, Neserin; Ruiz-Romero, Cristina; Blanco García, Francisco J; Englund, Martin; Önnerfjord, Patrik (Elsevier, 2023-12)
      [Abstract] Objective. To gain new insight into the molecular changes of the meniscus by comparing the proteome profiles of healthy controls with mild degeneration and end-stage osteoarthritis (OA). Method. We obtained ...

    • What did we learn from 'omics' studies in osteoarthritis 

      Ruiz-Romero, Cristina; Rego-Pérez, Ignacio; Blanco García, Francisco J (Wolters Kluwer, 2018-01-01)
      [Abstract] Purpose of review: 'Omics' technologies developed for the massive analysis of the major biologically relevant molecules (genes, proteins, metabolites) have been applied to the study of osteoarthritis (OA) for ...