Now showing items 1-20 of 123

    • A MicroRNA transcription factor blueprint for early atrial arrhytmogenic remodeling 

      Torrado, Mario; Franco, Diego; Lozano-Belasco, Estefanía; Hernández-Torres, Francisco; Calviño-Santos, Ramón; Aldama López, Guillermo; Centeno, Alberto; Castro-Beiras, Alfonso; Mikhailov, Alexander T. (Hindawi, 2015)
      [Abstract] Spontaneous self-terminating atrial fibrillation (AF) is one of the most common heart rhythm disorders, yet the regulatory molecular mechanisms underlying this syndrome are rather unclear. MicroRNA (miRNA) ...
    • A novel heterozygous intronic mutation in the FBN1 gene contributes to FBN1 RNA missplicing events in the Marfan syndrome 

      Torrado, Mario; Maneiro, Emilia; Trujillo-Quintero, Juan Pablo; Evangelista, Arturo; Mikhailov, Alexander T.; Monserrat Iglesias, Lorenzo (Hindawi, 2018)
      [Abstract] Marfan syndrome (MFS) is an autosomal dominantly inherited connective tissue disorder, mostly caused by mutations in the fibrillin-1 (FBN1) gene. We, by using targeted next-generation sequence analysis, identified ...
    • Adecuación del tratamiento de los pacientes hipertensos con síndrome metabólico 

      Barrios, Vivencio; Escobar, Carlos; Calderón, Alberto; Llisterri, José L.; Alegría, Eduardo; Muñiz, Javier; Matalí, Arantxa (Elsevier, 2007)
      [Resumen] Fundamento y objetivo. El objetivo de este estudio ha sido conocer el tratamiento de los pacientes hipertensos con síndrome metabólico (SM) asistidos en atención primaria y el grado de control de la presión ...
    • Aortic injuries in crush trauma patients: different mechanism, different management 

      Mosquera, Victor X.; Marini Díaz, Milagros; Muñiz, Javier; López-Pérez, José Manuel; Gulías, Daniel; Cuenca, José J. (Elsevier, 2011)
      [Abstract] Background. The objective of this study is to report the clinical and radiological characteristics and early and long-term survival of a series of acute traumatic aortic injuries (ATAI) in crush trauma patients, ...
    • Association of body mass index with clinical outcomes in patients with atrial fibrillation: a report from the FANTASIIA Registry 

      Bertomeu-González, Vicente; Moreno-Arribas, José; Esteve-Pastor, María Asunción; Roldán Rabadán, Inmaculada; Muñiz, Javier; Raña-Míguez, Paula; Ruiz Ortiz, Martín; Cequier, Ángel; Bertomeu Martínez, Vicente; Badimón, Lina; Anguita, Manuel; Lip, Gregory Y. H.; Marín, Francisco (NLM, 2019-12-24)
      [Abstract] Background. Obesity and atrial fibrillation (AF) frequently coexist and independently increase mortality. We sought to assess the association between obesity and adverse events in patients receiving oral ...
    • Blood pressure and lipid goal attainment in the hypertensive population in the primary care setting in Spain 

      Barrios, Vivencio; Escobar, Carlos; Llisterri, José L.; Echarri, Rocío; Alegría, Eduardo; Muñiz, Javier; Matalí, Arantxa (Wiley, 2007-05-10)
      [Abstract] Although blood pressure (BP) control is crucial in hypertensive patients, clinical practice guidelines agree that the goal of treatment should be aimed at not only decreasing BP but reducing global cardiovascular ...
    • Blunt traumatic aortic injuries of the ascending aorta and aortic arch: a clinical multicentre study 

      Mosquera Rodríguez, Víctor Xesús; Marini Díaz, Milagros; Muñiz, Javier; Gulias, Daniel; Asorey-Veiga, Vanesa; Adrio-Nazar, Belén; Herrera, José M.; Pradas-Montilla, Gonzalo; Cuenca, José J. (Elsevier, 2012)
      [Abstract] Objective. To report the clinical and radiological characteristics, management and outcomes of traumatic ascending aorta and aortic arch injuries. Methods. Historic cohort multicentre study including 17 major ...
    • Brachial pulse pressure in acute heart failure. Results of the Heart Failure Registry 

      Bonapace, Stefano; Rossi, Andrea; Laroche, Cécile; Crespo-Leiro, María Generosa; Piepoli, Massimo F.; Coats, Andrew J. S.; Dahlström, Ulf; Malek, Filip; Macarie, Cezar; Temporelli, Pier Luigi; Maggioni, Aldo P.; Tavazzi, Luigi (Willey Online Library, 2019-12-09)
      [Abstract] Aims To investigate the still uncertain independent prognostic impact of pulse pressure (PP) in acute heart failure (HF), in particular across the left ventricular ejection fraction (EF) phenotypes, and the ...
    • Calidad de vida relacionada con la salud de los pacientes con insuficiencia cardiaca crónica sistólica en España: resultados del estudio VIDA-IC 

      Comín, Josep; Anguita, Manuel; Formiga, Francesc; Almenar, Luis; Crespo-Leiro, María Generosa; Manzano, Luis; Muñiz, Javier; Chaves, José; Frutos, Trinidad de; Enjuanes, Cristina (Elsevier, 2015-12-23)
      [Resumen] Introducción y objetivos. La calidad de vida relacionada con la salud de los pacientes con insuficiencia cardiaca está afectada. Hay poca información sobre los factores clínicos asociados a esta mala calidad de ...
    • Cancer incidence in heart transplant recipients with previous neoplasia history 

      Delgado-Jiménez, Juan F.; Alonso-Pulpón, Luis; Mirabet, Sonia; Almenar-Bonet, Luis; Villa, F.P.; González-Vílchez, Francisco; Palomo, J.; Blasco-Peiró, Teresa; García-Cosío, M. Dolores; González-Costello, José; De la Fuente-Galán, Luis; Rábago, Gregorio; Lage-Gallé, Ernesto; Pascual Figal, Domingo A.; Molina, B.D.; Arizón-del-Prado, José M.; Muñiz, Javier; Crespo-Leiro, María Generosa (Wiley, 2016-02-03)
      [Abstract] Neoplasm history increases morbidity and mortality after solid organ transplantation and has disqualified patients from transplantation. Studies are needed to identify factors to be considered when deciding on ...
    • Cardiopatía estructural en pacientes anticoagulados con fibrilación auricular no valvular: prevalencia y perfil clínico en una muestra nacional 

      Ruiz Ortiz, Martín; Roldán, Inmaculada; Bertomeu, Vicente; Muñiz, Javier; Marín, Francisco; Anguita, Manuel (Sociedad Española de Cardiología, 2016-07-21)
    • Choice of new oral anticoagulant agents versus vitamin K antagonists in atrial fibrillation: FANTASIIA study 

      Moreno-Arribas, José; Bertomeu-González, Vicente; Anguita, Manuel; Cequier, Ángel; Muñiz, Javier; Castillo-Castillo, Jesús; Sanchis, Juan; Roldán, Inmaculada; Marín, Francisco; Bertomeu-Martínez, Vicente (SAGE, 2015-07-30)
      [Abstract] Introduction: Atrial fibrillation (AF) is associated with an increased risk of thromboembolic events. Many patients with AF receive chronic anticoagulation, either with vitamin K antagonists (VKAs) or with non-VKA ...
    • Chronic anemia in heart transplant patients: prevalence, risk factors, and prognostic significance 

      Cursack, Guillermo C.; Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Muñiz, Javier; Naya, Carmen; Grille Cancela, Zulaika; Rodríguez-Fernández, José Ángel; Marzoa Rivas, Raquel; Barge-Caballero, Eduardo; Ríos, Ramón; Estévez, Francisco; Cuenca, José J.; Juffé-Stein, Alberto; Castro-Beiras, Alfonso (Elsevier, 2007)
      [Abstract] Introduction and objectives. Data on chronic anemia following heart transplantation (HT) are scarce and contradictory. Our aims were to determine the prevalence of chronic anemia after HT, to identify predisposing ...
    • Clinical phenotypes and outcome of patients hospitalized for acute heart failure: the ESC Heart Failure Long‐Term Registry 

      Chioncel, Ovidiu; Mebazaa, Alexandre; Harjola, Veli-Pekka; Coats, Andrew J.; Piepoli, Massimo Francesco; Crespo-Leiro, María Generosa; Laroche, Cecile; Seferovic, Petar M.; Anker, Stefan; Ferrari, Roberto; Ruschitzka, Frank; López-Fernández, Silvia; Miani, Daniela; Filippatos, Gerasimos; Maggioni, Aldo P. (Wiley, 2017-04-30)
      [Abstract] Aims. To identify differences in clinical epidemiology, in‐hospital management and 1‐year outcomes among patients hospitalized for acute heart failure (AHF) and enrolled in the European Society of Cardiology ...
    • Control de presión arterial y lípidos y riesgo coronario en la población hipertensa asistida en Atención Primaria en España. Estudio PRESCOT 

      Barrios, Vivencio; Escobar, Carlos; Llisterri, José L.; Calderón, Alberto; Alegría, Eduardo; Muñiz, Javier; Matalí, Arantxa (Elsevier, 2007)
      [Resumen] Objetivo y métodos. El objetivo de este trabajo, de diseño transversal y multicéntrico, fue conocer el perfil de riesgo coronario de los pacientes hipertensos que acuden a la consulta de Atención Primaria, y ...
    • Cross‐sectional study about impact of parental smoking on rhinitis symptoms in children 

      Faraldo-García, A.; López-Silvarrey-Varela, Ángel; Pértega-Díaz, Sonia; Cruz, M.-J.; Sampedro, M.; Sánchez-Lastres, José Manuel; San-José González, M.A.; Bamonde-Rodríguez, Luis; Garnelo-Suárez, Luciano; Pérez-Castro, Teresa-Rosalía; Valdés Cuadrado, L.; González Barcala, F.-J- (Wiley, 2017-03-17)
      [Abstract] Objective. Assess the prevalence of rhinitis and exposure to environmental tobacco smoke (ETS) of children in our community and its relationship with symptoms of rhinitis Methods (design, setting, participants, ...
    • ¿Cuántos pacientes selecciono para mi estudio? 

      Muñiz, Javier; Santiago-Pérez, M.I. (Elsevier, 2006)
      [Resumen] Introducción. Después de haber trabajado uno de los autores durante años en una unidad de apoyo a la investigación en un hospital grande, llegó al convencimiento de que esta pregunta, y sus variantes, es, ...
    • Current antiarrhythmic therapy for nonvalvular atrial fibrillation in Spain: data from the FANTASIIA registry 

      Roldán, Inmaculada; Anguita, Manuel; Marín, Francisco; Quesada, María Angustias; Camacho Siles, José; Peinado, Rafael; Bertomeu, Vicente; Cequier, Ángel; Badimón, Lina; Muñiz, Javier (Elsevier, 2015-06-18)
      [Abstract] Introduction and objectives. Recently, there have been many developments in the management of nonvalvular atrial fibrillation, antiarrhythmic and anticoagulant therapy, and nonpharmacological treatment, but these ...
    • El desarrollo de la ciencia ocupacional fuera del ámbito anglófono: promoviendo la colaboración global 

      Magalhaes, Lilian; Farias, Lisette; Rivas-Quarneti, Natalia; Alvarez, Liliana; Serrata Malfitano, Ana Paula (Taylor & Francis Group, 2018)
      [Resumen] El desarrollo de la ciencia ocupacional en países no anglófonos enfrenta constantes barreras que impactan su participación en instancias de colaboración global, en la difusión del conocimiento y en el diálogo ...
    • Detection of protein interactions based on GFP fragment complementation by fluorescence microscopy and spectrofluorometry 

      Torrado, Mario; Iglesias Reinoso, Raquel; Mikhailov, Alexander T. (Future Science, 2008)
      [Abstract] We have developed a set of simple modifications of the green fluorescent protein (GFP)fragment reassembly assay in bacteria that permits: (i)fluorescent microscopy visualization of GFP reassembly only 1-2 h after ...