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Differences in the Clinical Profile and Management of Atrial Fibrillation According to Gender. Results of the REgistro GallEgo Intercéntrico de Fibrilación Auricular (REGUEIFA) Trial

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http://hdl.handle.net/2183/28522
Atribución 4.0 Internacional (CC BY 4.0)
Except where otherwise noted, this item's license is described as Atribución 4.0 Internacional (CC BY 4.0)
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Title
Differences in the Clinical Profile and Management of Atrial Fibrillation According to Gender. Results of the REgistro GallEgo Intercéntrico de Fibrilación Auricular (REGUEIFA) Trial
Author(s)
Durán-Bobín, Olga
Elices-Teja, Juliana
González-Melchor, Laila
Vázquez-Caamaño, María
Fernández-Obanza, Emiliano
González-Babarro, Eva
Cabanas-Grandío, Pilar
Piñeiro-Portela, Miriam
Prada-Delgado, Oscar
Gutiérrez-Feijoo, Mario
Freire, Evaristo
Díaz-Castro, Oscar
Muñiz, Javier
García-Seara, Javier
González-Juanatey, Carlos
Date
2021-08-27
Citation
Durán-Bobín, O.; Elices-Teja, J.; González-Melchor, L.; Vázquez-Caamaño, M.; Fernández-Obanza, E.; González-Babarro, E.; Cabanas-Grandío, P.; Piñeiro-Portela, M.; Prada-Delgado, O.; Gutiérrez-Feijoo, M.; Freire, E.; Díaz-Castro, O.; Muñiz, J.; García-Seara, J.; Gonzalez-Juanatey, C. Differences in the Clinical Profile and Management of Atrial Fibrillation According to Gender. Results of the REgistro GallEgo Intercéntrico de Fibrilación Auricular (REGUEIFA) Trial. J. Clin. Med. 2021, 10, 3846. https://doi.org/10.3390/jcm10173846
Abstract
[Abstract] To analyze the clinical profile and therapeutic strategy in atrial fibrillation (AF) according to gender in a contemporaneous patient cohort a prospective, multicenter observational study was performed on consecutive patients diagnosed with AF and assessed by cardiology units in the region of Galicia (Spain). A total of 1007 patients were included, of which 32.3% were women. The mean age of the women was significantly greater than that of the men (71.6 versus 65.7 years; p < 0.001), with a higher prevalence of hypertension (HTN) and valve disease. Women more often reported symptoms related to arrhythmia (28.2% in EHRA class I versus 36.4% in men), with a poorer level of symptoms (EHRA classes IIb and III). Thromboembolic risk was significantly higher among women (CHA2DS2-VASc 3 ± 1.3 versus 2 ± 1.5), in the same way as bleeding risk (HAS-BLED 0.83 ± 0.78 versus 0.64 ± 0.78) (p < 0.001), and women more often received anticoagulation therapy (94.1% versus 87.6%; p = 0.001). Rhythm control strategies proved significantly less frequent in women (55.8% versus 66.6%; p = 0.001), with a lesser electrical cardioversion (ECV) rate (18.4% versus 27.3%; p = 0.002). Perceived health status was poorer in women. Women were older and presented greater comorbidity than men, with a greater thromboembolic and bleeding risk. Likewise, rhythm control strategies were less frequent than in men, despite the fact that women had poorer perceived quality of life and were more symptomatic.
Keywords
Anticoagulation
Atrial fibrillation
Gender
Rhythm control
 
Editor version
https://doi.org/10.3390/jcm10173846
Rights
Atribución 4.0 Internacional (CC BY 4.0)
ISSN
2077-0383

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