• Classical and nonclassical intercellular communication in senescence and ageing 

      Fafián Labora, Juan Antonio; O'Loghlen, Ana (Cell Press, 2020-06-03)
      [Abstract] Intercellular communication refers to the different ways through which cells communicate with each other and transfer a variety of messages. These communication methods involve a number of different processes ...
    • Influence of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Vitro and their Role in Ageing 

      Fafián Labora, Juan Antonio; Morente-López, Miriam; Sánchez-Dopico, María José; Arntz, O.J.; Van de Loo, F.J.; De-Toro, Javier; Arufe, M.C. (Springer Nature, 2020-01-03)
      [Abstract] Introduction: This study assessed whether mesenchymal stem cell (MSC)-derived extracellular vesicles influenced ageing and pluripotency markers in cell cultures where they are added. Methods: MSC-derived ...
    • NF-κB/IKK Activation by Small Extracellular Vesicles Within the SASP 

      Fafián Labora, Juan Antonio; O'Loghlen, Ana (Wiley, 2021-06-29)
      [Abstract] Cellular senescence plays an important role in different biological and pathological conditions. Senescent cells communicate with their microenvironment through a plethora of soluble factors, metalloproteases ...