Listar GI-TCMR - Artigos por data de publicación
Mostrando ítems 21-40 de 130
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Multilineage differentiation potential of cells isolated from the human amniotic membrane
(Wiley, 2010-11-01)[Abstract] The human amniotic membrane (HAM) contains two cell types from different embryological origins. Human amnion epithelial cells (hAECs) are derived from the embryonic ectoderm, while human amnion mesenchymal stromal ... -
Quantification of cells expressing mesenchymal stem cell markers in healthy and osteoarthritic synovial membranes
(Journal of Rheumatology Publishing Company, 2010-11-15)[Abstract] Objective. To quantify cells expressing mesenchymal stem cell (MSC) markers in synovial mem- branes from human osteoarthritic (OA) and healthy joints. Methods. Synovial membranes from OA and healthy joints were ... -
Isolation and characterization of mesenchymal stem cells from human amniotic membrane
(Mary Ann Liebert, 2011-01-04)[Abstract] Introduction: The human amniotic membrane is a highly abundant and readily available tissue that may be useful for regenerative medicine and cell therapy. Aim: To compare two previously published protocols for ... -
Human amniotic membrane as an alternative source of stem cells for regenerative medicine
(Elsevier, 2011-02-19)[Abstract] The human amniotic membrane (HAM) is a highly abundant and readily available tissue. This amniotic tissue has considerable advantageous characteristics to be considered as an attractive material in the field of ... -
Tissue array analysis for the differentiation of gliosis from gliomas
(Spandidos, 2011-03-22)[Abstract] The aim of this study was to provide a methodology to make a clear distinction between malignant tumors and morphologically similar benign processes, by examining the expression of EGFR, VEGF, HIF1-α, survivin, ... -
Bone marrow cells immunomagnetically selected for CD271+ antigen promote in vitro the repair of articular cartilage defects
(Mary Ann Liebert, 2011-03-22)[Abstract] Objective: The purposes of this project were to quantify the cells expressing the mesenchymal stem cell (MSC) marker CD271 in synovial membranes from human osteoarthritic (OA) and healthy joints, and to determine ... -
Umbilical Cord as a Mesenchymal Stem Cell Source for Treating Joint Pathologies
(Baishideng, 2011-06-18)[Abstract] Articular cartilage disorders and injuries often result in life-long chronic pain and compromised quality of life. Regrettably, the regeneration of articular cartilage is a continuing challenge for biomedical ... -
Analysis of the Chondrogenic Potential and Secretome of Mesenchymal Stem Cells Derived from Human Umbilical Cord Stroma
(Mary Ann Liebert, 2011-06-28)[Abstract] Mesenchymal stem cells (MSCs) from umbilical cord stroma were isolated by plastic adherence and characterized by flow cytometry, looking for cells positive for OCT3/4 and SSEA-4 as well as the classic MSC markers ... -
Proteome analysis during chondrocyte differentiation in a new chondrogenesis model using human umbilical cord stroma mesenchymal stem cells
(American Society for Biochemistry and Molecular Biology, 2011-10-17)[Abstract] Umbilical cord stroma mesenchymal stem cells were differentiated toward chondrocyte-like cells using a new in vitro model that consists of the random formation of spheroids in a medium supplemented with fetal ... -
Evaluation of the adenocarcinoma-associated gene AGR2 and the intestinal stem cell marker LGR5 as biomarkers in colorectal cancer
(MDPI, 2012-04-05)[Abstract] We aim to estimate the diagnostic performances of anterior gradient homolog-2 (AGR2) and Leucine-rich repeat-containing-G-protein-coupled receptor 5 (LGR5) in peripheral blood (PB) as mRNA biomarkers in colorectal ... -
Cryopreservation effect on proliferative and chondrogenic potential of human chondrocytes isolated from superficial and deep cartilage
(Bentham Open, 2012-04-06)[Abstract] Objectives: To compare the proliferative and chondrogenic potential of fresh and frozen chondrocytes isolated from superficial and deep articular cartilage biopsies. Materials and Methodology: The study ... -
Characterization of microRNA expression profiles in normal and osteoarthritic human chondrocytes
(BioMed Central, 2012-08-12)[Abstract] Background. Osteoarthritis (OA) is a multifactorial disease characterized by destruction of the articular cartilage due to environmental, mechanical and genetic components. The genetics of OA is complex and ... -
Effects of severe hypoxia on bone marrow mesenchymal stem cells differentiation potential
(Hindawi, 2013-06-30)[Abstract] Background. The interests in mesenchymal stem cells (MSCs) and their application in cell therapy have resulted in a better understanding of the basic biology of these cells. Recently hypoxia has been indicated ... -
Lamin A deregulation in human mesenchymal stem cells promotes an impairment in their chondrogenic potential and imbalance in their response to oxidative stress
(Elsevier, 2013-07-26)[Abstract] In the present study, we examined the effect of the over-expression of LMNA, or its mutant form progerin (PG), on the mesoderm differentiation potential of mesenchymal stem cells (MSCs) from human umbilical cord ... -
Proteomic applications in the study of human mesenchymal stem cells
(Multidisciplinary Digital Publishing Institute, 2014-02-07)Mesenchymal stem cells (MSCs) are undifferentiated cells with an unlimited capacity for self-renewal and able to differentiate towards specific lineages under appropriate conditions. MSCs are, a priori, a good target for ... -
Effect of hydrogen sulfide sources on inflammation and catabolic markers on interleukin 1β-stimulated human articular chondrocytes
(Elsevier, 2014-07)[Abstract] Objective. Hydrogen sulfide (H2S), the third gasotransmitter together with NO and CO, is emerging as a regulator of inflammation. To test if it might offer therapeutic value in the treatment of osteoarthritis ... -
Influence of flap prefabrication on seeding of subcutaneously injected mesenchymal stem cells in microvascular beds in rats
(Wolter Kluwer Health, 2014-08)[Abstract] Background: In this article, the authors investigated whether the prefabrication of an autologous pedicled flap by isolation from the surrounding with artificial skin substitutes would increase mesenchymal ... -
Alternative protocols to induce chondrogenic differentiation: transforming growth factor-β superfamily
(Springer, 2014-09-10)[Abstract] Mesenchymal stem cells (MSCs) are an accepted candidate for cell-based therapy of multiple diseases. The interest in MSCs and their possible application in cell therapy have resulted in a better understanding ... -
Spanish Rheumatology Society and Hospital Pharmacy Society Consensus on recommendations for biologics optimization in patients with rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis
(Oxford University Press, 2014-12-19)[Abstract] Objective. The aim of this study was to establish guidelines for the optimization of biologic therapies for health professionals involved in the management of patients with RA, AS and PsA. Methods. Recommendations ... -
Clinical profile, level of affection and therapeutic management of patients with osteoarthritis in primary care: the spanish multicenter study EVALÚA
(Elsevier, 2015-04-16)[Abstract] Objective. To determine the clinical profile, degree of involvement and management in patients with knee, hip or hand osteoarthritis. Methods. Observational study (health centres from 14 autonomous regions, n ...