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Characterizing the Invasive Tumor Front of Aggressive Uterine Adenocarcinoma and Leiomyosarcoma
(Frontiers, 2021)
[Abstract] The invasive tumor front (the tumor–host interface) is vitally important in malignant cell progression and metastasis. Tumor cell interactions with resident and infiltrating host cells and with the surrounding ...
Epigenetic Landscape in Blood Leukocytes Following Ketosis and Weight Loss Induced by a Very Low Calorie Ketogenic Diet (VLCKD) in Patients With Obesity
(Elsevier, 2021)
[Abstract] Background:The molecular mechanisms underlying the potential health benefits of a ketogenic diet areunknown and could be mediated by epigenetic mechanisms.Objective:To identify the changes in the obesity-related ...
npcure: An R Package for Nonparametric Inference in Mixture Cure Models
(Technische Universitaet Wien, 2021)
[Abstract] Mixture cure models have been widely used to analyze survival data with a cure fraction. They assume that a subgroup of the individuals under study will never experience the event (cured subjects). So, the goal ...
Estimating Lengths-Of-Stay of Hospitalized COVID-19 Patients Using a Non-parametric Model: A Case Study in Galicia (Spain)
(Cambridge University Press, 2021)
[Abstract] Estimating the lengths-of-stay (LoS) of hospitalised COVID-19 patients is key for predicting the hospital beds’ demand and planning mitigation strategies, as overwhelming the healthcare systems has critical ...
A Product-Limit Estimator of the Conditional Survival Function When Cure Status Is Partially Known
(Wiley, 2021-03-01)
[Abstract] We introduce a nonparametric estimator of the conditional survival function in the mixture cure model for right-censored data when cure status is partially known. The estimator is developed for the setting of a ...