Listar GI- NANOSELF4BIO - Artigos por título
Mostrando ítems 6-25 de 45
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Carbon Vacancies Steer the Activity in Dual Ni Carbon Nitride Photocatalysis
(Wiley-VCH, 2023-07-06)[Abstract]: The manipulation of carbon nitride (CN) structures is one main avenue to enhance the activity of CN-based photocatalysts. Increasing the efficiency of photocatalytic heterogeneous materials is a critical step ... -
Chemoselective Esterification of Natural and Prebiotic 1,2-Amino Alcohol Amphiphiles in Water
(ACS Publications, 2023)[Abstract] In cells, a vast number of membrane lipids are formed by the enzymatic O-acylation of polar head groups with acylating agents such as fatty acyl-CoAs. Although such ester-containing lipids appear to be a requirement ... -
Concise, Single-Step Synthesis of Sulfur-Enriched Graphene: Immobilization of Molecular Clusters and Battery Applications
(Wiley-VCH, 2020-02-11)[Abstract]: The concise synthesis of sulfur-enriched Graphene for battery applications is reported. The direct treatment of graphene oxide (GO) with the commercially available Lawesson’s reagent produced sulfur-enriched-reduced ... -
Covalent functionalisation controlled by molecular design for the aptameric recognition of serotonin in graphene-based field-effect transistors
(2023-09-19)[Abastract]: In the last decade, solution-gated graphene field effect transistors (GFETs) showed their versatility in the development of a miniaturized multiplexed platform for electrophysiological recordings and sensing. ... -
Dendrimers: Exploring Their Wide Structural Variety and Applications
(MDPI, 2023-11-09)[Abstract] Dendrimers constitute a distinctive category of synthetic materials that bear resemblance to proteins in various aspects, such as discrete structural organization, globular morphology, and nanoscale dimensions. ... -
Development of New Non-viral Systems for Genetic Modification of Senescent Cells
(Cell Press, 2023-03-20)[Abstract] Senescence is a process characterized by a prolonged irreversible cell-cycle arrest. The accumulation of senescent cells in tissues is related to aging and to the development of age-related diseases. Recently, ... -
Effects of rAAV-Mediated sox9 Overexpression on the Biological Activities of Human Osteoarthritic Articular Chondrocytes in Their Intrinsic Three-Dimensional Environment
(MDPI, 2019)[Abstract] Gene therapy for osteoarthritis offers powerful, long-lasting tools that are well adapted to treat such a slow, progressive disorder, especially those therapies based on the clinically adapted recombinant ... -
Electrochemically Controlled Cleavage of Imine Bonds on a Graphene Platform: Towards New Electro-Responsive Hybrids for Drug Release
(Royal Society of Chemistry, 2020-11-25)[Abstract] Graphene-based materials are particularly suitable platforms for the development of new systems able to release drugs upon the application of controlled electrochemical stimuli. Herein, we report a new ... -
Enhanced Chondrogenic Differentiation Activities in Human Bone Marrow Aspirates via sox9 Overexpression Mediated by pNaSS-Grafted PCL Film-Guided rAAV Gene Transfer
(MDPI, 2020)[Abstract] Background: The delivery of therapeutic genes in sites of articular cartilage lesions using non-invasive, scaffold-guided gene therapy procedures is a promising approach to stimulate cartilage repair while ... -
Gene-Activated Hyaluronic Acid-Based Cryogels for Cartilage Tissue Engineering
(Elsevier, 2023)[Abstract] Articular cartilage injuries are very frequent lesions that if left untreated may degenerate into osteoarthritis. Gene transfer to mesenchymal stem cells (MSCs) provides a powerful approach to treat these lesions ... -
Graphene for Implantable Biosensors
(Grupo Español del Carbón, 2021-06)[Abstract]: In this review, we will provide a comprehensive insight on the current research si-tuations and future challenges for the graphene-based implantable biosensors. We intro-duce the use of graphene derivatives for ... -
Graphene, Other Carbon Nanomaterials and the Immune System: Toward Nanoimmunity-By-Design
(IOP Publishing, 2020-07-13)[Abstract]: Carbon-based materials (CBMs), such as graphene, nanodiamonds, carbon fibers, and carbon dots, have attracted a great deal scientific attention due to their potential as biomedical tools. Following exposure, ... -
High-Yield Preparation of Exfoliated 1T-MoS2 with SERS Activity
(American Chemical Society, 2019-07-17)[Abstract]: Molybdenum disulfide (MoS2), a promising two-dimensional transition-metal dichalcogenide, presents a challenge in the tuning of its optoelectronic and chemical properties. Herein, we demonstrate an efficient ... -
Hydrogel-Guided, rAAV-Mediated IGF-I Overexpression Enables Long-Term Cartilage Repair and Protection against Perifocal Osteoarthritis in a Large-Animal Full-Thickness Chondral Defect Model at One Year In Vivo
(Wiley-VCH, 2021)[Abstract] The regeneration of focal articular cartilage defects is complicated by the reduced quality of the repair tissue and the potential development of perifocal osteoarthritis (OA). Biomaterial-guided gene therapy ... -
Improved Chondrogenic Differentiation of rAAV SOX9-Modified Human MSCs Seeded in Fibrin-Polyurethane Scaffolds in a Hydrodynamic Environment
(MDPI, 2018)[Abstract] The repair of focal articular cartilage defects remains a problem. Combining gene therapy with tissue engineering approaches using bone marrow-derived mesenchymal stem cells (MSCs) may allow the development of ... -
In Situ Synthesis of Artificial Lipids
(Elsevier, 2022-09-15)[Abstract] Lipids constitute one of the most enigmatic family of biological molecules. Although the importance of lipids as basic units of compartmental structure and energy storage is well-acknowledged, deciphering the ... -
Intrinsic and Selective Activity of Functionalized Carbon Nanotube/Nanocellulose Platforms Against Colon Cancer Cells
(Elsevier, 2022-01-25)[Abstract] Given their large surface area and versatile chemical reactivity, single-walled carbon nanotubes (SWCNTs) are regarded as the basis of new pharmacological complexes. In this study, SWCNTs are chemically ... -
Light-driven, heterogeneous organocatalysts for C–C bond formation toward valuable perfluoroalkylated intermediates
(American Association for the Advancement of Science, 2020-11-11)The favorable exploitation of carbon nitride (CN) materials in photocatalysis for organic synthesis requires the appropriate fine-tuning of the CN structure. Here, we present a deep investigation of the structure/activity ... -
Mass Spectrometry of Carbohydrate-Protein Interactions on a Glycan Array Conjugated to CVD Graphene Surfaces
(IOP, 2020-01-06)[Abstract]: Mass spectrometry (MS) is a valuable tool for functional genomic, proteomic, and glycomic studies. In particular, the combination of MS with microarrays is a powerful technique for analyzing the activity of ... -
Metal Nanoparticles/MoS2 Surface-Enhanced Raman Scattering- Based Sandwich Immunoassay for α‑Fetoprotein Detection
(American Chemical Society, 2021-02-13)[Abstract]: The detection of cancer biomarkers at an early stage of tumor development is vital for effective diagnosis and treatment of cancer. Current diagnostic tools can often detect cancer only when the biomarker levels ...