• Bidirectional Modulation of Neuronal Cells Electrical and Mechanical Properties Through Pristine and Functionalized Graphene Substrates 

      Zummo, Francesca; Esposito, Pietro; Hou, Huilei; Wetzl, Cecilia; Rius, Gemma; Tkatchenko, Raphaela; Guimerà, Anton; Godignon, Philippe; Prato, Maurizio; Prats Alfonso, Elisabet; Criado, Alejandro; Scaini, Denis (Frontiers, 2022-01-11)
      [Abstract] In recent years, the quest for surface modifications to promote neuronal cell interfacing and modulation has risen. This course is justified by the requirements of emerging technological and medical approaches ...
    • Development of new non-viral systems for genetic modification of senescent cells 

      López-Seijas, Junquera; Miranda-Balbuena, Diego; Iglesias-Fente, Alba; Sacristán-Santos, Marta; Carballo-Pedrares, Natalia; Arufe, M.C.; Rey-Rico, Ana; Fafián Labora, Juan Antonio (Cell Press, 2023-03-20)
      [Abstract] Senescence is a process characterized by a prolonged irreversible cell-cycle arrest. The accumulation of senescent cells in tissues is related to aging and to the development of age-related diseases. Recently, ...
    • In Situ Synthesis of Artificial Lipids 

      Lomba-Riego, Lucía; Calviño Sanlés, Esther; Brea, Roberto J. (Elsevier, 2022-09-15)
      [Abstract] Lipids constitute one of the most enigmatic family of biological molecules. Although the importance of lipids as basic units of compartmental structure and energy storage is well-acknowledged, deciphering the ...
    • Intrinsic and Selective Activity of Functionalized Carbon Nanotube/Nanocellulose Platforms Against Colon Cancer Cells 

      González-Domínguez, José Miguel; Grasa, Laura; Frontiñán, Javier; Abás, Elisa; Domínguez-Alfaro, Antonio; Mesonero, J. E.; Criado, Alejandro; Ansón-Casaos, Alejandro (Elsevier, 2022-01-25)
      [Abstract] Given their large surface area and versatile chemical reactivity, single-walled carbon nanotubes (SWCNTs) are regarded as the basis of new pharmacological complexes. In this study, SWCNTs are chemically ...
    • Polymer-Induced Biofilms for Enhanced Biocatalysis 

      Adoni, Pavan; Romanyuk, Andrey; Overton, Tim W.; Fernández-Trillo, Paco (Royal Society of Chemistry, 2022-07-21)
      [Abstract] The intrinsic resilience of biofilms to environmental conditions makes them an attractive platform for biocatalysis, bioremediation, agriculture or consumer health. However, one of the main challenges in these ...
    • Vermellogens and the Development of CB[8]-Based Supramolecular Switches Using pH-Responsive and Non-Toxic Viologen Analogues 

      Barravecchia Prado, Liliana Inés; Blanco-Gómez, Arturo; Neira, Iago; Skackauskaite, Raminta; Vila García, Alejandro; Rey-Rico, Ana; Peinador, Carlos; García, Marcos D. (ACS, 2022-10-07)
      [Abstract] We present herein the “vermellogens”, a new class of pH-responsive viologen analogues, which replace the direct linking between para-substituted pyridinium moieties within those by a hydrazone functional group. ...