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Peritoneal dialysis Is an independent factor associated to lower intima media thickness in dialysis patients free from previous cardiovascular disease
dc.contributor.author | Borrás, Mercé | |
dc.contributor.author | Cambray, Serafí | |
dc.contributor.author | Crespo-Masip, María | |
dc.contributor.author | Pérez-Fontán, Miguel | |
dc.contributor.author | Bozic, Milica | |
dc.contributor.author | Bermúdez-López, Marcelino | |
dc.contributor.author | Fernández, Elvira | |
dc.contributor.author | Betriu, Ángels | |
dc.contributor.author | Valdivieso, José M. | |
dc.date.accessioned | 2022-01-25T11:06:16Z | |
dc.date.available | 2022-01-25T11:06:16Z | |
dc.date.issued | 2018-12-04 | |
dc.identifier.citation | Borràs M, Cambray S, Crespo-Masip M, Pérez-Fontán M, Bozic M, Bermudez-López M, Fernández E, Betriu À, Valdivielso JM. Peritoneal dialysis Is an independent factor associated to lower intima media thickness in dialysis patients free from previous cardiovascular disease. Front Physiol. 2018 Dec 4;9:1743. | es_ES |
dc.identifier.issn | 1664-042X | |
dc.identifier.uri | http://hdl.handle.net/2183/29487 | |
dc.description.abstract | [Abstract] Carotid intima media thickness (cIMT) displays prognostic value as a marker of cardiovascular risk in dialysis patients. However, few data are available regarding the impact of dialysis modality on cIMT. The aim of this study is to determine whether the modality of dialysis influences cIMT values. We compared 237 peritoneal dialysis (PD) and 451 hemodialysis (HD) patients without previous cardiovascular disease included in NEFRONA, a prospective, observational and multicenter study. This cross sectional study included the determination of cIMT in 6 carotid territories by arterial ultrasound. cIMT was determined in territories without atheroma plaque and averaged. A second analysis was performed using all territories, giving a truncated cIMT value of 1,5 mm to territories presenting with atheroma plaque. Age and plaque presence at baseline were the clinical variables more closely associated to cIMT in dialysis patients. The evaluation of the impact of the modality of dialysis on cIMT showed that PD patients had lower cIMT than HD patients, both in territories with no plaques and when using truncated cIMT values. No differences were found between right and left sides, neither in cIMT or truncated cIMT values. Lineal multivariate analysis adjusted by several clinical variables showed a statistically significant association of PD with a lower cIMT (slope -0.036; SD 0.010). These results were also confirmed when truncated cIMT values were used. We conclude that the modality of dialysis has an impact on cITM. HD patients have greater global cIMT than PD patients, and PD is and independent factor associated with a lower cIMT. | es_ES |
dc.description.sponsorship | This study was funded by the intramural program of the IRBLleida, the Instituto de Salud Carlos III (RETIC RD16/0009/0011, PI15/00960, and PI16/01354), and FEDER funds ‘A way to make Europe. | es_ES |
dc.description.sponsorship | info:eu-repo/grantAgreement/MINECO/Programa Estatal de I+D+I Orientada a los Retos de la Sociedad/RD16%2F0009%2F0011/ES/Red de Investigacion Renal REDINREN | es_ES |
dc.description.sponsorship | info:eu-repo/grantAgreement/MINECO/Programa Estatal de I+D+I Orientada a los Retos de la Sociedad/PI15%2F00960/ES/Papel de la alfa sinucleina en la enfermedad renal crónica. Implicaciones en la patologia de la fibrosis renal | es_ES |
dc.description.sponsorship | info:eu-repo/grantAgreement/MINECO/Programa Estatal de I+D+I Orientada a los Retos de la Sociedad/PI16%2F01354/ES/Caracterización de un perfil lipidómico y lipídico de riesgo aterogénico y de morbimortalidad cardiovascular en la Enfermedad Renal Crónica (estadios 3 a 5) (estudio prospectivo NEFRONA) | |
dc.language.iso | eng | es_ES |
dc.publisher | Frontiers | es_ES |
dc.relation.uri | https://doi.org/10.3389/fphys.2018.01743 | es_ES |
dc.rights | Creative Commons Attribution 4.0 International License (CC-BY 4.0) | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Atherosclerosis | es_ES |
dc.subject | Cohorts study | es_ES |
dc.subject | Dialysis | es_ES |
dc.subject | Intima and media thickness | es_ES |
dc.subject | Ultrasound | es_ES |
dc.title | Peritoneal dialysis Is an independent factor associated to lower intima media thickness in dialysis patients free from previous cardiovascular disease | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.access | info:eu-repo/semantics/openAccess | es_ES |
UDC.journalTitle | Frontiers in Physiology | es_ES |
UDC.volume | 9 | es_ES |
UDC.startPage | 1743 | es_ES |
UDC.coleccion | Investigación | es_ES |
UDC.grupoInv | Enfermidades Endocrinas, Nutricionais e Metabólicas (INIBIC) | es_ES |
UDC.institutoCentro | INIBIC - Instituto de Investigacións Biomédicas de A Coruña | es_ES |
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