• Statin treatment withdrawal in ischemic stroke: a controlled randomized study 

  Blanco, Miguel; Nombela, Florentino; Castellanos, María del Mar; Rodríguez-Yáñez, Manuel; García-Gil, María del Mar; Leira, Rogelio; Lizasoain, Ignacio; Serena, Joaquín; Vivancos, José; Moro, María Ángeles; Dávalos, Antoni; Castillo, José (American Academy of Neurology, 2007-08-28)

  [Abstract] Background: Pretreatment with statins has been shown to reduce brain injury in cerebral ischemia. In this controlled randomized study, we investigated the influence of statin pretreatment and its withdrawal on ...

• High plasma glutamate concentrations are associated with infarct growth in acute ischemic stroke 

  Castellanos, María del Mar; Sobrino, Tomás; Pedraza, Salvador; Moldes, Octavio; Pumar, José Manuel; Silva, Yolanda; Serena, Joaquín; García-Gil, María del Mar; Castillo, José; Dávalos, Antoni (American Academy of Neurology, 2008-12-02)

  [Abstract] Background: Excitotoxic and inflammatory mechanisms have been demonstrated as mediating early neurologic deterioration (END) in patients with cerebral infarction. Here we investigate whether molecular markers ...

• Serum cellular fibronectin and matrix metalloproteinase-9 as screening biomarkers for the prediction of parenchymal hematoma after thrombolytic therapy in acute ischemic stroke: a multicenter confirmatory study 

  Castellanos, María del Mar; Sobrino, Tomás; Millán, Mónica; García, María M.; Arenillas, Juan; Nombela, Florentino; Brea, David; Pérez de la Ossa, Natalia; Serena, Joaquín; Vivancos, José; Castillo, José; Dávalos, Antoni (American Heart Association, 2007-05-03)

  [Abstract] Background and purpose: Plasma levels of cellular fibronectin (c-Fn) > or =3.6 microg/mL and of matrix metalloproteinase-9 (MMP-9) > or =140 ng/mL have been associated with parenchymal hematoma (PH) after ...

• Semi-intensive monitoring in acute stroke and long-term outcome 

  Silva, Yolanda; Puigdemont, Montserrat; Castellanos, María del Mar; Serena, Joaquín; Suñer, Rosa M.; García, María M.; Dávalos, Antoni (Karger, 2005-01-14)

  [Abstract] Background and purpose: Factors that determine the benefit of stroke units (SU) are unknown. The aim of our study was to analyze whether semi-intensive monitoring during the acute phase of stroke reduces mortality ...

• Microembolic signal monitoring in hemispheric acute ischaemic stroke: a prospective study 

  Serena, Joaquín; Segura, Tomás; Castellanos, María del Mar; Dávalos, Antoni (Karger, 2000-06-22)

  [Abstract] Background and purpose: There are few data on the occurrence of microembolic signals (MES) in the acute phase of ischaemic stroke. The objective of our work was to systematically study the frequency of MES ...

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