Listar GI-REACT! - Artigos por autor "Esteban-Gómez, David"

Mostrando ítems 21-40 de 61

    • endo- versus exo-Cyclic coordination in copper complexes with methylthiazolylcarboxylate tacn derivatives 

      Guillou, Amaury; Lima, Luís M. P.; Esteban-Gómez, David; Delgado, Rita; Platas-Iglesias, Carlos; Patinec, Véronique; Tripier, Raphaël (Royal Society of Chemistry, 2019-05-17)
      [Abstract] Three tacn (1,4,7-triazacyclononane)-based ligands substituted by methylthiazolylcarboxylate (tha) and/or methylthiazolyl (th) arms have been examined for copper complexation with the aim to study the impact of ...

    • Exceptionally inert lanthanide(III) PARACEST MRI contrast agents based on an 18-membered macrocyclic platform 

      Castro, Goretti; Regueiro-Figueroa, Martín; Esteban-Gómez, David; Bastida, Rufina; Macías, Alejandro; Pérez-Lourido, Paulo; Platas-Iglesias, Carlos; Valencia, Laura (Wiley, 2015-12-14)
      [Abstract] We report a macrocyclic ligand based on a 3,6,10,13-tetraaza-1,8(2,6)-dipyridinacyclotetradecaphane platform containing four hydroxyethyl pendant arms (L1) that forms extraordinary inert complexes with Ln3+ ions. ...

    • Expanding the Ligand Classes Used for Mn(II) Complexation: Oxa-aza Macrocycles Make the Difference 

      Kálmán, Ferenc; Nagy, Viktória; Uzal-Varela, Rocío; Pérez-Lourido, Paulo; Esteban-Gómez, David; Garda, Zoltán; Pota, Kristof; Mezei, Roland; Pallier, Agnès; Tóth, Éva; Platas-Iglesias, Carlos; Tircsó, Gyula (MDPI, 2021-03-10)
      [Abstract] We report two macrocyclic ligands based on a 1,7-diaza-12-crown-4 platform functionalized with acetate (𝑡O2DO2A²⁻) or piperidineacetamide (𝑡O2DO2AMᴾⁱᵖ) pendant arms and a detailed characterization of the ...

    • Gd3+-based magnetic resonance imaging contrast agent responsive to Zn2+ 

      Regueiro-Figueroa, Martín; Gündüz, Serhat; Patinec, Véronique; Logothetis, Nikos K.; Esteban-Gómez, David; Tripier, Raphaël; Angelovski, Goran; Platas-Iglesias, Carlos (American Chemical Society, 2015-10-15)
      [Abstract] We report the heteroditopic ligand H5L, which contains a DO3A unit for Gd3+ complexation connected to an NO2A moiety through a N-propylacetamide linker. The synthesis of the ligand followed a convergent route ...

    • High relaxivity Mn2+-based MRI contrast agents 

      Regueiro-Figueroa, Martín; Rolla, Gabriele A.; Esteban-Gómez, David; Blas, Andrés de; Rodríguez-Blas, Teresa; Botta, Mauro; Platas-Iglesias, Carlos (Wiley, 2014-12-16)
      [Abstract] Stable Mn2+ mono- and binuclear complexes containing pentadentate 6,6′-((methylazanediyl)bis(methylene)) dipicolinic acid coordinating units give remarkably high relaxivities due to the presence of two inner-sphere ...

    • Highly relaxing gadolinium based MRI contrast agents responsive to Mg2+ sensing 

      Abada, Sabah; Lecointre, Alexandre; Elhabiri, Mourad; Esteban-Gómez, David; Platas-Iglesias, Carlos; Tallec, Gaylord; Mazzanti, Marinella; Charbonnière, Loïc J. (Royal Society of Chemistry, 2012-04-28)
      [Abstract] A Gd complex based on a polyphosphonated pyridyl ligand shows a very high stability in aqueous solution (logKEuL = 25.7), a high relaxivity (8.5 mM−1 s−1 at 25 °C and 20 MHz) and a marked and selective relaxivity ...

    • Highly stable complexes of divalent metal ions (Mg2+, Ca2+, Cu2+, Zn2+, Cd2+, and Pb2+) with a dota‐like ligand containing a picolinate pendant 

      Regueiro-Figueroa, Martín; Ruscsák, Erika; Fra, Laura; Tircsó, Gyula; Tóth, Imre; Blas, Andrés de; Rodríguez-Blas, Teresa; Platas-Iglesias, Carlos; Esteban-Gómez, David (Wiley, 2014-12)
      [Abstract] The stability constants of complexes of the macrocyclic ligand do3a‐pic4– (H4do3a‐pic = 2,2′,2″‐{10‐[(6‐carboxypyridin‐2‐yl)methyl]‐1,4,7,10‐tetraazacyclododecane 1,4,7‐triyl}triacetic acid) with several divalent ...

    • Hyperfine coupling constants on inner‐sphere water molecules of GdIII‐based MRI contrast agents 

      Esteban-Gómez, David; Blas, Andrés de; Rodríguez-Blas, Teresa; Helm, Lothar; Platas-Iglesias, Carlos (Wiley, 2012-11-02)
      [Abstract] Herein we present a theoretical investigation of the hyperfine coupling constants (HFCCs) on the inner‐sphere water molecules of [Gd(H2O)8]3+ and different GdIII‐based magnetic resonance imaging contrast agents ...

    • Importance of outer-sphere and aggregation phenomena in the relaxation properties of phosphonated gadolinium complexes with potential applications as MRI contrast agents 

      Elhabiri, Mourad; Abada, Sabah; Sy, Mohamadou; Nonat, Aline; Choquet, Philippe; Esteban-Gómez, David; Cassino, Claudio; Platas-Iglesias, Carlos; Botta, Mauro; Charbonnière, Loïc J. (Wiley, 2015-04-10)
      [Abstract] A series composed of a tetra-, a tris- and a bisphosphonated ligand based on a pyridine scaffold (L4, L3 and L2, respectively) was studied within the frame of lanthanide (Ln) coordination. The stability constants ...

    • Inert macrocyclic Eu3+ complex with affirmative paraCEST features 

      Gambino, Tanja; Valencia, Laura; Pérez-Lourido, Paulo; Esteban-Gómez, David; Zaiss, Moritz; Platas-Iglesias, Carlos; Angelovski, Goran (Royal Society of Chemistry, 2020-06-21)
      [Abstract]: We report on a macrocyclic platform based on an 18-membered macrocycle that forms kinetically highly inert paramagnetic complexes and possesses an excellent outlook for the development of bioresponsive paraCEST ...

    • Lead(II) complexes of lateral macrobicyclic receptors that incorporate a crown moiety and a pyridine head unit 

      Esteban-Gómez, David; Enríquez-Pérez, Teresa; Ferreirós-Martínez, Raquel; Mato-Iglesias, Marta; Platas-Iglesias, Carlos; Blas, Andrés de; Rodríguez-Blas, Teresa (Wiley, 2010-11)
      [Abstract] The coordinative properties towards lead(II) of two lateral macrobicyclic receptors that incorporate either a 1,10‐diaza‐[15]crown‐5 (L7) or a 4,13‐diaza‐[18]crown‐6 (L8) fragment are reported. Spectrophotometric ...

    • Macrocyclic receptor showing improved PbII/ZnII and PbII/CaII selectivities 

      Ferreirós-Martínez, Raquel; Platas-Iglesias, Carlos; Blas, Andrés de; Esteban-Gómez, David; Rodríguez-Blas, Teresa (Wiley, 2010-05-31)
      [Abstract] Herein we report on the macrocyclic receptor N,N′‐bis[(6‐carboxy‐2‐pyridyl)methyl]‐1,10‐diaza‐15‐crown‐5 (H2bp15c5) and its coordination properties towards ZnII, CdII, PbII, and CaII. The stability constants of ...

    • Magnetic anisotropies in rhombic lanthanide(III) complexes do not conform to Bleaney’s theory 

      Castro, Goretti; Regueiro-Figueroa, Martín; Esteban-Gómez, David; Pérez-Lourido, Paulo; Platas-Iglesias, Carlos; Valencia, Laura (American Chemical Society, 2016-04-04)
      [Abstract] We report a complete set of magnetic susceptibilities of lanthanide complexes with a macrocyclic ligand based on a 3,6,10,13-tetraaza-1,8(2,6)-dipyridinacyclotetradecaphane platform containing four hydroxyethyl ...

    • Modeling the OEC with two new biomimetic models: preparations, structural characterization, and water photolysis studies of a Ba–Mn box type complex and a Mn4N6 planar-diamond cluster 

      Rouco, Lara; Fernández-García, M. Isabel; Pedrido, Rosa; Botana, Luis M.; Esteban-Gómez, David; Platas-Iglesias, Carlos; Maneiro, Marcelino (MDPI, 2018-09-07)
      [Abstract] The oxygen-evolving complex (OEC) is the native enzyme that catalyzes the oxidation of water in natural photosynthesis. Two new classes of manganese cluster complexes of formula Ba2Mn2L12(H3L1)2(CH3OH)4 1 and ...

    • On the Dissociation Pathways of Copper Complexes Relevant as Pet Imaging Agents 

      Uzal-Varela, Rocío; Patinec, Véronique; Tripier, Raphaël; Valencia, Laura; Maneiro, Marcelino; Canle, Moisés; Platas-Iglesias, Carlos; Esteban-Gómez, David; Iglesias, Emilia (Elsevier, 2022)
      [Abstract] Several bifunctional chelators have been synthesized in the last years for the development of new 64Cu-based PET agents for in vivo imaging. When designing a metal-based PET probe, it is important to achieve ...

    • Optimising the relaxivities of Mn2+ complexes by targeting human serum albumin (HSA) 

      Forgács, Attila; Tei, Lorenzo; Baranyai, Zsolt; Esteban-Gómez, David; Platas-Iglesias, Carlos; Botta, Mauro (Royal Society of Chemistry, 2017-07-14)
      [Abstract] We report two novel macrocyclic ligands based on the 1,4-DO2AM platform (1,4-DO2AM = 2,2′-(1,4,7,10-tetraazacyclododecane-1,4-diyl)diacetamide) and containing two benzyl groups attached either to the nitrogen ...

    • Phosphate and polyphosphate anion recognition by a dinuclear copper(ii) complex of an unsymmetrical squaramide 

      Esteves, Catarina V.; Costa, Judite; Esteban-Gómez, David; Lamosa, Pedro; Bernard, Hélène; Platas-Iglesias, Carlos; Tripier, Raphaël; Delgado, Rita (Royal Society of Chemistry, 2019-05-29)
      [Abstract] In the search for receptors suitable for the recognition of phosphate or polyphosphate anions, a new unsymmetrical squaramide-based ligand bearing dipicolylamine (dpa) and ethylpiperazine units (L) was designed ...

    • Receptor versus counterion: capability of N,N′‐Bis(2‐aminobenzyl)‐diazacrowns for giving endo‐ and/or exocyclic coordination of ZnII 

      Vaiana, Lea; Platas-Iglesias, Carlos; Esteban-Gómez, David; Avecilla, Fernando; Blas, Andrés de; Rodríguez-Blas, Teresa (Wiley, 2007-03-20)
      [Abstract] The structure of ZnII complexes with receptors L1 and L2[L1 = N,N′‐bis(2‐aminobenzyl)‐1,10‐diaza‐15‐crown‐5 and L2 = N,N′‐bis(2‐aminobenzyl)‐4,13‐diaza‐18‐crown‐6] was studied both in the solid state and in ...

    • Recognition of AMP, ADP and ATP through cooperative binding by Cu(II) and Zn(II) complexes containing urea and/or phenylboronic acid moieties 

      Carreira-Barral, Israel; Fernández-Pérez, María-Isabel; Mato-Iglesias, Marta; Blas, Andrés de; Platas-Iglesias, Carlos; Esteban-Gómez, David (MDPI, 2018)
      [Abstract] We report a series of Cu(II) and Zn(II) complexes with different ligands containing a dipicolyl unit functionalized with urea groups that may contain or not a phenylboronic acid function. These complexes were ...

    • Reinforced Ni(ɪɪ)-Cyclam Derivatives as Dual ¹H/¹⁹F MRI Probes 

      Pujales-Paradela, Rosa; Savic, Tanja; Brandariz, Isabel; Pérez-Lourido, Paulo; Angelovski, Goran; Esteban-Gómez, David; Platas-Iglesias, Carlos (Royal Society of Chemistry, 2019-03-11)
      [Abstract] Reinforced cross-bridged Ni²⁺-cyclam complexes were functionalised with pendant arms containing both amide protons and CF₃ groups that lead to a dual ¹H/¹⁹F response. The resulting complexes possess very high ...