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dc.contributor.authorRivero-Juárez, A.
dc.contributor.authorFrías, Mario
dc.contributor.authorLópez-López, Pedro
dc.contributor.authorBerenguer, Juan
dc.contributor.authorGarcía, Federico
dc.contributor.authorMacías, Juan
dc.contributor.authorAlcaraz, Begoña
dc.contributor.authorCastro-Iglesias, Ángeles
dc.contributor.authorCaballero-Gómez, Javier
dc.contributor.authorRivero, Antonio
dc.date.accessioned2021-10-27T07:15:27Z
dc.date.available2021-10-27T07:15:27Z
dc.date.issued2020-09-11
dc.identifier.citationRivero-Juárez A, Frías M, López-López P, Berenguer J, García F, Macías J, et al. Hepatitis E 3ra genotype infection in people living with HIV in Spain. Front Microbiol. 2020;11:564486es_ES
dc.identifier.issn1664-302X
dc.identifier.urihttp://hdl.handle.net/2183/28738
dc.description.abstract[Abstract] Background: The objective of our study was to assess the prevalence and incidence of HEV in people living with HIV (PLWH) in a Spanish national cohort. Methods: Retrospective longitudinal study including PLWH recruited in the cohort of adult HIV-infected patients of the AIDS Research Network in follow-up at 28 Spanish hospitals with available serum samples in 2014 and 2015. All samples were tested for HEV IgG, IgM, and RNA. Samples with detectable HEV viral loads were genotyped. Prevalence and incidence of HEV infection were calculated. Results: The study sample comprised 845 PLWH. At baseline, 101 patients were positive for HEV IgG antibodies (11.9%), none had HEV IgM antibodies, and 2 presented detectable HEV RNA (0.23%). Forty-two seroconverted for IgG, supposing a cumulative incidence of 5.7%. One subject was positive for IgM (0.13%), and 2 showed detectable HEV RNA (0.27%). One case was infected by the emergent HEV genotype 3ra. Conclusion: Our study identifies one case of HEV 3ra genotype infection, the main host of which is rabbit, showing a potential zoonotic role of this emerging genotype in Spain.es_ES
dc.description.sponsorshipInstituto de Salud Carlos III; RD16/0025/0017es_ES
dc.description.sponsorshipInstituto de Salud Carlos III; RD16/0025/0034es_ES
dc.description.sponsorshipInstituto de Salud Carlos III; RD16/0025/0040es_ES
dc.description.sponsorshipInstituto de Salud Carlos III; RD12/0017/0012es_ES
dc.description.sponsorshipInstituto de Salud Carlos III; PI16/01297es_ES
dc.description.sponsorshipJunta de Andalucía; PIN-0477-2017es_ES
dc.language.isoenges_ES
dc.publisherFrontierses_ES
dc.relation.urihttps://doi.org/10.3389/fmicb.2020.564486es_ES
dc.rightsAtribución 3.0 Españaes_ES
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.subjectHepatitis Ees_ES
dc.subjectHIVes_ES
dc.subjectSurveyes_ES
dc.subjectGenotype 3raes_ES
dc.subjectSeroprevalencees_ES
dc.titleHepatitis E 3ra genotype infection in people living with HIV in Spaines_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessinfo:eu-repo/semantics/openAccesses_ES
UDC.journalTitleFrontiers in Microbiologyes_ES
UDC.volume11es_ES
UDC.startPage564486es_ES


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