Hepatitis E 3ra genotype infection in people living with HIV in Spain
Ver/ abrir
Use este enlace para citar
http://hdl.handle.net/2183/28738Coleccións
- INIBIC-VC - Artigos [37]
Metadatos
Mostrar o rexistro completo do ítemTítulo
Hepatitis E 3ra genotype infection in people living with HIV in SpainAutor(es)
Data
2020-09-11Cita bibliográfica
Rivero-Juárez A, Frías M, López-López P, Berenguer J, García F, Macías J, et al. Hepatitis E 3ra genotype infection in people living with HIV in Spain. Front Microbiol. 2020;11:564486
Resumo
[Abstract] Background: The objective of our study was to assess the prevalence and incidence of HEV in people living with HIV (PLWH) in a Spanish national cohort.
Methods: Retrospective longitudinal study including PLWH recruited in the cohort of adult HIV-infected patients of the AIDS Research Network in follow-up at 28 Spanish hospitals with available serum samples in 2014 and 2015. All samples were tested for HEV IgG, IgM, and RNA. Samples with detectable HEV viral loads were genotyped. Prevalence and incidence of HEV infection were calculated.
Results: The study sample comprised 845 PLWH. At baseline, 101 patients were positive for HEV IgG antibodies (11.9%), none had HEV IgM antibodies, and 2 presented detectable HEV RNA (0.23%). Forty-two seroconverted for IgG, supposing a cumulative incidence of 5.7%. One subject was positive for IgM (0.13%), and 2 showed detectable HEV RNA (0.27%). One case was infected by the emergent HEV genotype 3ra.
Conclusion: Our study identifies one case of HEV 3ra genotype infection, the main host of which is rabbit, showing a potential zoonotic role of this emerging genotype in Spain.
Palabras chave
Hepatitis E
HIV
Survey
Genotype 3ra
Seroprevalence
HIV
Survey
Genotype 3ra
Seroprevalence
Versión do editor
Dereitos
Atribución 3.0 España
ISSN
1664-302X