Mostrando ítems 6-10 de 189

    • Increased synovial immunohistochemistry reactivity of TGF-β1 in erosive peripheral psoriatic arthritis 

      Pinto-Tasende, José A.; Fernández-Moreno, Mercedes; Vázquez-Mosquera, María E.; Fernández-López, Carlos; Oreiro, Natividad; de-Toro, Javier; Blanco García, Francico J (BioMed Central, 2023-03-30)
      [Abstract] Background: Immune and non-immune cells contribute to the pathology of chronic arthritis, and they can contribute to tissue remodeling and repair as well as disease pathogenesis. The present research aimed to ...
    • Is osteoarthritis a mitochondrial disease?: what is the evidence 

      Fernández-Moreno, Mercedes; Rego-Pérez, Ignacio; Blanco García, Francico J (Wolters Kluwer, 2022-01)
      [Abstract] Propose of review: To summarize the evidence that suggests that osteoarthritis (OA) is a mitochondrial disease. Recent findings: Mitochondrial dysfunction together with mtDNA damage could contribute to cartilage ...
    • Expert recommendations on the interleukin 6 blockade in patients with rheumatoid arthritis 

      Tornero Molina, Jesús; Balsa Criado, Alejandro; Blanco García, Francico J; Blanco Alonso, Ricardo; Bustabad, Sagrario; Calvo Alen, Jaime; Corominas, Héctor; Fernández Nebro, Antonio; Román Ivorra, José Andrés; Sanmartí, Raimon (Elsevier, 2020-07)
      [Abstract] Objective: To draft recommendations on interleukin 6 (IL-6) blockade in rheumatoid arthritis (RA), based on best evidence and experience. Methods: A group of 10 experts on IL-6 blockade in RA was selected. ...
    • Proteomic profiling of human menisci from mild joint degeneration and end-stage osteoarthritis versus healthy controls 

      Paz-González, Rocío; Turkiewicz, Aleksandra; Ali, Neserin; Ruiz-Romero, Cristina; Blanco García, Francisco J; Englund, Martin; Önnerfjord, Patrik (Elsevier, 2023-12)
      [Abstract] Objective. To gain new insight into the molecular changes of the meniscus by comparing the proteome profiles of healthy controls with mild degeneration and end-stage osteoarthritis (OA). Method. We obtained ...
    • Machine-learning predicted and actual 2-year structural progression in the IMI-APPROACH cohort 

      Jansen, Mylène P.; Wirth, Wolfgang; Bacardit, Jaume; van Helvoort, Eefje M.; Marijnissen, Anne C.A.; Kloppenburg, Margreet; Blanco García, Francico J; Haugen, Ida K.; Berenbaum, Francis; Ladel, Christoph H.; Loef, Marieke; Lafeber, Floris P.J.G.; Welsing, Paco M.J.; Mastbergen, Simon C.; Roemer, Frank W. (AME, 2023-05)
      [Abstract] In the Innovative Medicine’s Initiative Applied Public-Private Research enabling OsteoArthritis Clinical Headway (IMI-APPROACH) knee osteoarthritis (OA) study, machine learning models were trained to predict the ...