ListarReumatoloxía por tema "Apoptosis"
Mostrando ítems 1-6 de 6
-
Antifibrotic effect of brown algae-derived fucoidans on osteoarthritic fibroblast-like synoviocytes
(Elsevier, 2022-01-12)[Abstract] Synovial fibrosis is a pathological process which contributes to joint pain and stiffness in several musculoskeletal disorders. Fucoidans, sulfated polysaccharides found in brown algae, have recently emerged as ... -
Generating Rho-0 cells using mesenchymal stem cell lines
(PLoS, 2016-10-20)[Abstract] Introduction, The generation of Rho-0 cells requires the use of an immortalization process, or tumor cell selection, followed by culture in the presence of ethidium bromide (EtBr), incurring the drawbacks its ... -
Is osteoarthritis a mitochondrial disease?: what is the evidence
(Wolters Kluwer, 2022-01)[Abstract] Propose of review: To summarize the evidence that suggests that osteoarthritis (OA) is a mitochondrial disease. Recent findings: Mitochondrial dysfunction together with mtDNA damage could contribute to cartilage ... -
Mitochondrial activity is modulated by TNFα and IL-1β in normal human chondrocyte cells
(Elsevier, 2006-05-05)[Abstract] Objective. Pro-inflammatory cytokines play an important role in osteoarthritis (OA). In osteoarthritic cartilage, chondrocytes exhibit an alteration in mitochondrial activity. This study analyzes the effect of ... -
Mitochondrial DNA (mtDNA) haplogroups J and H are differentially associated with the methylation status of articular cartilage: potential role in apoptosis and metabolic and developmental processes
(Wiley, 2019-02-12)[Abstract] Objective. To analyze the influence of mitochondrial genome variation on the DNA methylome of articular cartilage. Methods. DNA methylation profiling was performed using data deposited in the NCBI Gene ... -
Nitric Oxide Compounds Have Different Effects Profiles on Human Articular Chondrocyte Metabolism
(BioMed Central, 2013-09-11)[Abstract] Introduction. The pathogenesis of osteoarthritis (OA) is characterized by the production of high amounts of nitric oxide (NO), as a consequence of up-regulation of chondrocyte-inducible nitric oxide synthase ...
