• Intraneural IFG-1 in cryopreserved nerve isografts increase neural regeneration and functional recovery in the rat sciatic nerve 

      González Porto, Sara Alicia; Doménech, Nieves; Blanco García, Francisco J; Centeno, Alberto; Rivadulla, Casto; Álvarez Jorge, Álvaro; Sánchez Ibáñez, Jacinto; Rendal Vázquez, María Esther (Oxford, 2018-07-27)
      [Abstract] Background: Insulin-like growth factor 1 (IGF-1) was found to stimulate Schwann cell mitosis. Exogenous IGF-1 may improve nerve regeneration after cryopreservation. Objective: To evaulate the effect of ...
    • Mitochondrial DNA Impact on Joint Damaged Process in a Conplastic Mouse Model After Being Surgically Induced With Osteoarthritis 

      Scotece, Morena; Rego-Pérez, Ignacio; Lechuga-Vieco, Ana Victoria; Centeno, Alberto; Jiménez-Gómez, María Concepción; Filgueira-Fernández, P.; Vaamonde-García, Carlos; Enríquez, José Antonio; Blanco García, Francisco J (Nature, 2021-04-27)
      [Abstract] It has been suggested that mitochondrial dysfunction and mtDNA variations may contribute to osteoarthritis (OA) pathogenesis. However, the causative link to support this claim is lacking. Here, we surgically-induced ...
    • The mitochondrial inhibitor oligomycin induces an inflammatory response in the rat knee joint 

      Vaamonde-García, Carlos; Loureiro, Jesús; Valcárcel Ares, Marta Noa; Riveiro Naveira, Romina R.; Ramil-Gómez, Olalla; Hermida-Carballo, Laura; Centeno, Alberto; Meijide-Faílde, Rosa; Blanco García, Francisco J; López-Armada, María José (BioMed Central, 2017-06-12)
      [Abstract] Background. Recent findings support a connection between mitochondrial dysfunction and activation of inflammatory pathways in articular cells. This study investigates in vivo in an acute model whether ...