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Practical guidelines for diagnosis and treatment of acromegaly
(Elsevier, 2013-10)
[Abstract] Acromegaly and gigantism are due to excess GH secretion, usually by a pituitary adenoma. It is an uncommon disease.
Diagnosis is made by showing elevated GH and IGF-I levels in patients with a clinical picture ...
Treatment adherence to pegvisomant in patients with acromegaly in Spain: PEGASO study
(Springer, 2019-02-13)
[Abstract] PURPOSE: The burden of chronic daily subcutaneous administration of pegvisomant on adherence has not been previously studied. This study was aimed to determine the adherence to pegvisomant treatment in acromegaly ...
Cost-effectiveness analysis of preoperative treatment of acromegaly with somatostatin analogue on surgical outcome
(Elsevier, 2015-08-20)
[Abstract] Context. There is no uniform standard of care for acromegaly. Due to the high costs involved, steps must be taken to ensure the cost-effective delivery of treatment.
Objective. Taking the results of an earlier ...
Effectiveness of lanreotide autogel 120 mg at extended dosing intervals for acromegaly
(Springer, 2020-07-28)
[Abstract]
Purpose. Recent data indicate that extended dosing intervals (EDIs) with lanreotide autogel 120 mg are effective and well-received among patients with acromegaly who have achieved biochemical control with monthly ...
Factors associated with therapeutic response in acromegaly diagnosed in the elderly in Spain
(Frontiers, 2022-09-16)
[Abstract] Context: Some reports suggest that acromegaly in elderly patients has a more benign clinical behavior and could have a better response to first-generation long-acting somatostatin receptor ligands (SRL). However, ...
Pituitary MRI features in acromegaly resulting from ectopic GHRH secretion from a neuroendocrine tumor: analysis of 30 cases
(Oxford University Press on behalf of the Endocrine Society, 2022-05-04)
[Abstract] Context: Ectopic acromegaly is a consequence of rare neuroendocrine tumors (NETs) that secrete GHRH. This abnormal GHRH secretion drives GH and IGF-1 excess, with a clinical presentation similar to classical ...