• Factors associated with therapeutic response in acromegaly diagnosed in the elderly in Spain 

      Biagetti, Betina; Iglesias, Pedro; Villar-Taibo, Rocío; Moure, María-Dolores; Paja, Miguel; Araújo-Castro, Marta; Ares, Jessica; Álvarez-Escola, Cristina; Vicente, Almudena; Álvarez Guivernau, Élia; Novoa-Testa, Iria; Guerrero Pérez, Fernando; Cámara, Rosa; Lecumberri, Beatriz; García Gómez, Carlos; Bernabéu, Ignacio; Manjón, Laura; Gaztambide, Sonia; Cordido, Fernando; Webb, Susan; Webb, Susan M.; Menéndez-Torre, Edelmiro Luis; Díez, Juan J.; Simó, Rafael; Puig-Domingo, Manel (Frontiers, 2022-09-16)
      [Abstract] Context: Some reports suggest that acromegaly in elderly patients has a more benign clinical behavior and could have a better response to first-generation long-acting somatostatin receptor ligands (SRL). However, ...
    • FNDC5 expression and circulating irisin levels are modified by diet and hormonal conditions in hypothalamus, adipose tissue and muscle 

      Varela-Rodríguez, Bárbara María; Pena-Bello, Lara; Juiz-Valiña, Paula; Vidal Bretal, Beatriz; Cordido, Fernando; Sangiao-Alvarellos, Susana (Nature, 2016-07-19)
      [Abstract] Irisin is processed from fibronectin type III domain-containing protein 5 (FNDC5). However, a controversy exists concerning irisin origin, regulation and function. To elucidate the relationship between serum ...
    • Ghrelin neutralization during fasting-refeeding cycle impairs the recuperation of body weight and alters hepatic energy metabolism 

      Sangiao-Alvarellos, Susana; Helming, Steffen; Vázquez, María J.; Klussmann, Sven; Cordido, Fernando (Elsevier, 2011)
      [Abstract] Ghrelin, a hormone whose levels increase during food deprivation, plays a pivotal role in the regulation of food intake, energy metabolism and storage, as well as in insulin sensitivity. Here, we investigated ...
    • Giant non-functioning pituitary adenoma: clinical characteristics and therapeutic outcomes 

      Iglesias, Pedro; Arcano, Karina; Triviño, Vanessa; Guerrero-Pérez, Fernando; Rodríguez Berrocal, Víctor; Vior, Carlos; Cordido, Fernando; Villabona, Carles; Díez, Juan J. (Thieme, 2020-01-02)
      [Abstract] Background: Giant pituitary adenoma (≥4 cm) is a rare tumor whose clinical features and prognosis are not well known. Aim: To evaluate the clinical characteristics and therapeutic outcomes of giant non-functioning ...
    • Gonadotrophin-releasing hormone agonist-induced pituitary adenoma apoplexy and casual finding of a parathyroid carcinoma: a case report and review of literature 

      Triviño, Vanessa; Fidalgo, Olga; Juane, Antía; Pombo-Otero, Jorge; Cordido, Fernando (Baishideng Publishing Group, 2019-10-26)
      [Absatract] BACKGROUND Pituitary apoplexy represents one of the most serious, life threatening endocrine emergencies that requires immediate management. Gonadotropin-releasing hormone agonist (GnRHa) can induce pituitary ...
    • Importance of exercise in the control of metabolic and inflammatory parameters at the moment of onset in type 1 diabetic subjects 

      Martínez-Ramonde, T.; Alonso, N.; Cordido, Fernando; Cervelló, E.; Cañizares, Angelina; Martínez-Peinado, P.; Sempere, J.M.; Roche, E. (Thieme, 2014-05-05)
      [Abstract] The onset of type 1 diabetes coincides with the final phase of β-cell destruction. In some cases, this period is characterized by the presence of a functional reserve of β-cells, favouring an adequate metabolic ...
    • Observational, multicentre study to evaluate the effectiveness in routine clinical practice of Lanreotide Autogel 120 mg at extended dosing intervals (>4 weeks) for the treatment of acromegaly: SOMACROL study 

      Álvarez Escolá, Cristina; Fajardo, Carmen; Marazuela, Mónica; Cordido, Fernando; Venegas, Eva; Pablos Velasco, Pedro de; Piedrola Maroto, Gonzalo; Olvera Márquez, María del Pilar; Pavón de Paz, Isabel; Carvalho, Davide; Romero, Carmen; De la Cruz, Guillermo; Bernabéu, Ignacio (Bioscientifica, 2018-05)
    • Oral glucose-stimulated growth hormone (GH) test in adult GH deficiency patients and controls: potential utility of a novel test 

      Pena-Bello, Lara; Seoane-Pillado, Teresa; Sangiao-Alvarellos, Susana; Outeiriño-Blanco, Elena; Varela-Rodríguez, Bárbara María; Juiz-Valiña, Paula; Cordido, María; Cordido, Fernando (Elsevier para European Federation of Internal Medicine, 2017-06-09)
      [Abstract] Context. The diagnosis of adult GH deficiency requires confirmation with a GH stimulation test. Oral glucose (OG) administration affects GH secretion, initially decreasing and subsequently stimulating GH ...
    • Pituitary MRI features in acromegaly resulting from ectopic GHRH secretion from a neuroendocrine tumor: analysis of 30 cases 

      Potorac, Iulia; Bonneville, Jean-François; Daly, Adrian F.; de Herder, Wouter; Fainstein-Day, Patricia; Chanson, Philippe; Korbonits, Marta; Cordido, Fernando; Lamback, Elisa Baranski; Abid, Mohamed; Raverot, Véronique; Raverot, Gerald; Anda Apiñániz, Emma; Caron, Philippe; Du Boullay, Helene; Bidlingmaier, Martin; Bolanowski, Marek; Laloi-Michelin, Marie; Borson-Chazot, Francoise; Chabre, Olivier; Christin-Maitre, Sophie; Briet, Claire; Díaz-Soto, Gonzalo; Bonneville, Fabrice; Castinetti, Frederic; Gadelha, Mônica R.; Oliveira Santana, Nathalie; Stelmachowska-Banaś, Maria; Gudbjartsson, Tomas; Villar-Taibo, Rocío; Zornitzki, Taiba; Tshibanda, Luaba; Petrossians, Patrick; Beckers, Albert (Oxford University Press on behalf of the Endocrine Society, 2022-05-04)
      [Abstract] Context: Ectopic acromegaly is a consequence of rare neuroendocrine tumors (NETs) that secrete GHRH. This abnormal GHRH secretion drives GH and IGF-1 excess, with a clinical presentation similar to classical ...
    • Practical guidelines for diagnosis and treatment of acromegaly 

      Cordido, Fernando; García-Arnés, Juan Antonio; Marazuela, Mónica; Torres Vela, Elena (Elsevier, 2013-10)
      [Abstract] Acromegaly and gigantism are due to excess GH secretion, usually by a pituitary adenoma. It is an uncommon disease. Diagnosis is made by showing elevated GH and IGF-I levels in patients with a clinical picture ...
    • Serum levels of the adipomyokine irisin in patients with chronic kidney disease 

      Rodríguez-Carmona, Ana; Pérez-Fontán, Miguel; Sangiao-Alvarellos, Susana; García Falcón, María Teresa; Pena-Bello, Lara; López-Muñiz, Andrés; Cordido, Fernando (Elsevier, 2016-12-14)
      [Abstract] Background. Irisin is an adipomyokine with claimed anti-obesity and anti-diabetic effects. This hormone has been insufficiently studied in patients with advanced chronic kidney disease (CKD). Objective. To ...
    • The SEEN comprehensive clinical survey of adult obesity: executive summary 

      Ballesteros-Pomar, María D.; Vilarrasa, Nuria; Rubio Herrera, Miguel Ángel; Barahona, María José; Bueno, Marta; Caixás, Assumpta; Calañas Continente, Alfonso; Ciudin, Andreea; Cordido, Fernando; Hollanda, Ana de; Díaz, María Jesús; Flores, Lliliam; García Luna, Pedro Pablo; García Pérez-Sevillano, Fernando; Goday, Albert; Lecube, Albert; López Gómez, Juan José; Miñambres, Inka; Morales Gorria, María José; Morinigo, Rosa; Nicolau, Joana; Pellitero, Silvia; Salvador, Javier; Valdés, Sergio; Bretón Lesmes, Irene (Elsevier, 2021-04-09)
      [Abstract] Obesity is one of the great challenges in healthcare nowadays with important implications for health so requiring comprehensive management. This document aims to establish practical and evidence-based recommendations ...
    • Thyroid function alteration in obesity and the effect of bariatric surgery 

      Cordido, María; Juiz-Valiña, Paula; Urones Cuesta, Paula; Sangiao-Alvarellos, Susana; Cordido, Fernando (MDPI, 2022-02-28)
      [Abstract] The most common endocrine disease in obesity is hypothyroidism and secondary endocrine alterations, including abnormal thyroid function, are frequent in obesity. It is unclear whether impaired thyroid function ...
    • Treatment adherence to pegvisomant (somavert®) in Spain: PEGASO study 

      Cámara, Rosa; Venegas, Eva; García-Arnés, Juan Antonio; Cordido, Fernando; Aller, J.; Martín, Víctor; Sánchez-Cenizo, Laura; Mir, Nuria (Oxford, 2017)
    • Treatment adherence to pegvisomant in patients with acromegaly in Spain: PEGASO study 

      Cámara, Rosa; Venegas, Eva; García-Arnés, Juan Antonio; Cordido, Fernando; Aller, J.; Samaniego, M. Luz; Mir, Nuria; Sánchez-Cenizo, Laura (Springer, 2019-02-13)
      [Abstract] PURPOSE: The burden of chronic daily subcutaneous administration of pegvisomant on adherence has not been previously studied. This study was aimed to determine the adherence to pegvisomant treatment in acromegaly ...
    • Treatment with growth hormone for adults with growth hormone deficiency syndrome: benefits and risks 

      Díez, Juan José; Sangiao-Alvarellos, Susana; Cordido, Fernando (MDPI, 2018-03-17)
      [Abstract] Pharmacological treatment of growth hormone deficiency (GHD) in adults began in clinical practice more than 20 years ago. Since then, a great volume of experience has been accumulated on its effects on the ...
    • Weight-related quality of life in spanish obese subjects suitable for bariatric surgery is lower than in their North American counterparts: a case–control study 

      Caixás, Assumpta; Lecube, Albert; Morales, María-José; Calañas Continente, Alfonso; Moreiro, José; Cordido, Fernando; Díaz, María-Jesús; Másmiquel, Lluís; Moreno, Basilio; Vidal, Josep; Goday, Albert; Arrizabalaga, Juan-José; García-Luna, Pedro-Pablo; Iglesias, Paloma; Burguera, Bartolomé; Rubio, Miguel-Ángel; Monereo, Susana; Crosby, Ross D.; Kolotkin, Ronette L. (Springer, 2012-10-23)
      [Abstract] Background: Obesity impairs quality of life, but the perception of the impairment could be different from one country to another. The purpose was to compare weight-related quality of life (QOL) between cohorts ...