Now showing items 1-6 of 6

    • CD105+-mesenchymal stem cells migrate into osteoarthritis joint: an animal model 

      Fernández-Pernas, Pablo; Rodríguez-Lesende, Iván; Fuente, Alexandre de la; Mateos, Jesús; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J; Arufe, M.C. (PLoS, 2017-11-30)
      [Abstract] Mesenchymal stem cells are being the focus of connective tissue technology and regenerative medicine, presenting a good choice cell source for improving old and well recognized techniques of cartilage defect ...
    • Differentiation of human mesenchymal stromal cells cultured on collagen sponges for cartilage repair 

      Sanjurjo-Rodríguez, Clara; Martínez Sánchez, Adela Helvia; Hermida Gómez, Tamara; Fuentes Boquete, Isaac Manuel; Díaz-Prado, Silvia; Blanco García, Francisco J (Sociedad Española de Histología e Ingeniería Tisular, 2016)
      [Abstract] Aim: The aim of this study was to evaluate proliferation and chondrogenic differentiation of human bone-marrow mesenchymal stromal cells (hBMSCs) cultured on collagen biomaterials. Materials and methods: ...
    • Generation of mesenchymal cell lines derived from aged donors 

      Piñeiro-Ramil, María; Sanjurjo-Rodríguez, Clara; Rodríguez-Fernández, Silvia; Castro Viñuelas, Rocío; Hermida Gómez, Tamara; Blanco García, Francisco J; Fuentes Boquete, Isaac Manuel; Díaz-Prado, Silvia (MDPI, 2021-10-01)
      [Abstract] Background: Mesenchymal stromal cells (MSCs) have the capacity for self-renewal and multi-differentiation, and for this reason they are considered a potential cellular source in regenerative medicine of cartilage ...
    • Human cartilage engineering in an in vitro repair model using collagen scaffolds and mesenchymal stromal cells 

      Sanjurjo-Rodríguez, Clara; Castro Viñuelas, Rocío; Hermida Gómez, Tamara; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J; Díaz-Prado, Silvia (Ivyspring, 2017-09-28)
      [Abstract] The purpose of this study was to investigate cartilage repair of in vitro lesion models using human bone marrow mesenchymal stromal cells (hBMSCs) with different collagen (Col) scaffolds. Lesions were made ...
    • Mesenchymal stromal cells for articular cartilage repair: preclinical studies 

      Fernández-Pernas, Pablo; Barrachina, Laura; Marquina, Maribel; Rodellar, C.; Arufe, M.C.; Costa, Cristina (AO Research Institute Davos (ARI), 2020-08-26)
      [Abstract] Rheumatic diseases such as osteoarthritis (OA) are a major social and economic burden because of the population aging and the lack of curative solutions. An effective cell therapy may be the best treatment ...
    • Usefulness of mesenchymal cell lines for bone and cartilage regeneration research 

      Piñeiro-Ramil, María; Sanjurjo-Rodríguez, Clara; Castro Viñuelas, Rocío; Rodríguez-Fernández, Silvia; Fuentes Boquete, Isaac Manuel; Blanco García, Francisco J; Díaz-Prado, Silvia (MDPI, 2019-12-13)
      [Abstract] The unavailability of sufficient numbers of human primary cells is a major roadblock for in vitro repair of bone and/or cartilage, and for performing disease modelling experiments. Immortalized mesenchymal ...