Terapia Celular e Medicina Rexenerativa: Envíos recentes

Mostrando ítems 36-40 de 116

    • Hydrogel-based localized nonviral gene delivery in regenerative medicine approaches: an overview 

      Carballo-Pedrares, Natalia; Fuentes Boquete, Isaac Manuel; Díaz-Prado, Silvia; Rey-Rico, Ana (MDPI, 2020-08-10)
      [Abstract] Hydrogel-based nonviral gene delivery constitutes a powerful strategy in various regenerative medicine scenarios, as those concerning the treatment of musculoskeletal, cardiovascular, or neural tissues disorders ...

    • Small extracellular vesicles have GST activity and ameliorate senescence-related tissue damage 

      Fafián Labora, Juan Antonio; Rodríguez-Navarro, José Antonio; O’Loghlen, Ana (Elsevier, 2020-07-07)
      [Abstract] Aging is a process of cellular and tissue dysfunction characterized by different hallmarks, including cellular senescence. However, there is proof that certain features of aging and senescence can be ameliorated. ...

    • Regulation of Angiogenesis Discriminates Tissue Resident MSCs from Effective and Defective Osteogenic Environments 

      Cuthbert, R.J.; Jones, Elena; Sanjurjo-Rodríguez, Clara; Lotfy, A.; Ganguly, P.; Churchman, S.M.; Kastana, P.; Tan, H.B.; McGonagle, Dennis; Papadimitriou, E.; Giannoudis, P.V. (MDPI, 2020-05-28)
      [Abstract] Background: The biological mechanisms that contribute to atrophic long bone non-union are poorly understood. Multipotential mesenchymal stromal cells (MSCs) are key contributors to bone formation and are ...

    • Immortalizing mesenchymal stromal cells from aged donors while keeping their essential features 

      Piñeiro-Ramil, María; Castro Viñuelas, Rocío; Sanjurjo-Rodríguez, Clara; Rodríguez-Fernández, Silvia; Hermida Gómez, Tamara; Blanco García, Francisco J; Fuentes Boquete, Isaac Manuel; Díaz-Prado, Silvia (Hindawi, 2020-06-16)
      [Abstract] Human bone marrow-derived mesenchymal stromal cells (MSCs) obtained from aged patients are prone to senesce and diminish their differentiation potential, therefore limiting their usefulness for osteochondral ...

    • Hydrogen sulfide biosynthesis is impaired in the osteoarthritic joint 

      Burguera, Elena F.; Vela Anero, Ángela; Gato Calvo, Lucía; Vaamonde-García, Carlos; Meijide-Faílde, Rosa; Blanco García, Francisco J (Springer, 2019-11-16)
      [Abstract] Osteoarthritis (OA) is the most common form of arthritis and it is a leading cause of disability in the elderly. Its complete etiology is not known although there are several metabolic, genetic, epigenetic, and ...