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Regulation of Angiogenesis Discriminates Tissue Resident MSCs from Effective and Defective Osteogenic Environments
(MDPI, 2020-05-28)
[Abstract] Background: The biological mechanisms that contribute to atrophic long bone non-union
are poorly understood. Multipotential mesenchymal stromal cells (MSCs) are key contributors to bone
formation and are ...
Preventing heart failure: a position paper of the Heart Failure Association in collaboration with the European Association of Preventive Cardiology
(Oxford Academic, 2022-01-27)
[Abstract] The heart failure epidemic is growing and its prevention, in order to reduce associated hospital readmission rates and its clinical and economic burden, is a key issue in modern cardiovascular medicine. The ...
Individualizing the treatment of patients with heart failure with reduced ejection fraction: a journey from hospitalization to long-term outpatient care
(Taylor & Francis, 2022-08-31)
[Abstract] Introduction: Despite the relevant advances achieved thanks to the traditional step-by-step therapeutic approach, heart failure with reduced ejection fraction (HFrEF) remains associated with considerable morbidity ...
Advanced heart failure: definition, epidemiology, and clinical course
(Elsevier, 2021-07-15)
[Abstract] Advanced heart failure (HF) is characterized by a progressive worsening of symptoms disabling for daily life, refractory to all therapies, and with high mortality. These patients may be candidates for life-prolonging ...
All-trans retinoic acid inhibits migration and invasiveness of rheumatoid fibroblast-like synoviocytes
(American Society for Pharmacology and Experimental Therapeutics (ASPET), 2020-02)
[Abstract] Fibroblast-like synoviocytes (FLSs) are pivotal in inflammation and joint damage of rheumatoid arthritis (RA). They acquire an active and aggressive phenotype, displaying increased migration and invasiveness and ...
Sexual Dysfunction in Ostomized Patients: A Systematized Review
(MDPI, 2021-04-29)
[Abstract]
The impact of an ostomy has a negative influence on sexuality. Healthcare professionals focus the care on surgery, and consider the sexual life is little relevant to the patient recovery. The aim of this ...
Cardiogenic shock code 2023: expert document for a multidisciplinary organization that allows quality care
(Elsevier, 2022-12-21)
[Abstract] Despite the efforts made to improve the care of cardiogenic shock (CS) patients, including the development of mechanical circulatory support (MCS), the prognosis of these patients continues to be poor. In this ...
A model for prediction of in-hospital mortality in patients with subarachnoid hemorrhage
(Springer, 2020-07-15)
[Abstract] Background: Despite being a rare cause of stroke, spontaneous subarachnoid hemorrhage (SAH) is associated with high mortality rates. The prediction models that are currently being used on SAH patients are ...
Interactions between rheumatoid arthritis antibodies are associated with the response to anti-tumor necrosis factor therapy
(Springer, 2021-04-21)
[Abstract] Background. Blocking of the Tumor Necrosis Factor (TNF) activity is a successful therapeutic approach for 50–60% of rheumatoid arthritis (RA) patients. However, there are yet no biomarkers to stratify patients ...